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Cellular Immunology

Handbook of Physiology, Cell Physiology

  1. Ephraim Fuchs

Published Online: 1 JAN 2011

DOI: 10.1002/cphy.cp140119

Comprehensive Physiology

Comprehensive Physiology

How to Cite

Fuchs, E. 2011. Cellular Immunology. Comprehensive Physiology. 743–785.

Author Information

  1. Johns Hopkins Oncology Center, Baltimore, Maryland

Publication History

  1. Published Online: 1 JAN 2011

Abstract

The sections in this article are:

  • 1
    Overview
    • 1.1
      The Adaptive Immune System Combats Intracellular and Extracellular Pathogens
    • 1.2
      The Antigen-Specific Receptors on B and T Lymphocytes Bind Distinct Ligands
    • 1.3
      MHC Class I and II Molecules Present Antigens to CD8+ and CD4+ T Cells, Respectively
    • 1.4
      The Clonal Selection Theory of Acquired Immunity Provides a Mechanism for Immunologic Specificity and Memory
    • 1.5
      Lymphocytes Require Two Signals for Activation to Effector Function
    • 1.6
      Summary
  • 2
    Members of the Immunoglobulin Superfamily
    • 2.1
      Immunoglobulins
    • 2.2
      T Cell Receptor Structure, Genes, and the Generation of T Cell Receptor Diversity
    • 2.3
      Major Histocompatibility Complex (MHC) Molecules
  • 3
    Lymphocyte Development
    • 3.1
      Monoclonal Antibodies and Flow Cytometry Facilitate the Identification of Distinct Lymphocyte Subpopulations
    • 3.2
      B Cell Development
    • 3.3
      T Cell Development
  • 4
    Peripheral Lymphoid Organs and Lymphocyte Circulation
  • 5
    Lymphocyte Activation
    • 5.1
      Antigen Processing and Presentation: The Generation of Signal 1
    • 5.2
      T Cell Activation
    • 5.3
      8 Cell Activation
  • 6
    T Cell Effector Functions
    • 6.1
      Cytokine Secretion
    • 6.2
      Delayed-Type Hypersensitivity (DTH)
    • 6.3
      Cytolysis
    • 6.4
      Control of T Cell Effector Functions
  • 7
    Immunological Memory
    • 7.1
      B Cells: Somatic Mutation, Affinity Maturation, and Memory
    • 7.2
      T Cell Memory
  • 8
    Immunological Tolerance
  • 9
    Immunological Self/Nonself Discrimination
  • 10
    Future Directions