Back Cover: Fluorescent Nanodiamonds with Bioorthogonally Reactive Protein-Resistant Polymeric Coatings (ChemPlusChem 1/2014)

Authors

  • Dr. Ivan Rehor,

    1. Institute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.cz
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  • Dr. Hana Mackova,

    1. Institute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410
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  • Dr. Sergey K. Filippov,

    1. Institute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410
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  • Dr. Jan Kucka,

    1. Institute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410
    2. Nuclear Physics Institute, v.v.i. The Academy of Sciences of the Czech Republic, 250 68 Rez near Prague (Czech Republic)
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  • Dr. Vladimir Proks,

    1. Institute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410
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  • Jitka Slegerova,

    1. Institute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.cz
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  • Dr. Stuart Turner,

    1. EMAT, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium)
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  • Prof. Gustaaf Van Tendeloo,

    1. EMAT, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium)
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  • Dr. Miroslav Ledvina,

    1. Institute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.cz
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  • Dr. Martin Hruby,

    Corresponding author
    1. Institute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410
    • Martin Hruby, Institute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410

      Petr Cigler, Institute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.cz

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  • Dr. Petr Cigler

    Corresponding author
    1. Institute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.cz
    • Martin Hruby, Institute of Macromolecular Chemistry, v.v.i. The Academy of Sciences of the Czech Republic, Heyrovskeho nam. 2, 162 06 Prague 6 (Czech Republic), Fax: (+420) 296-809-410

      Petr Cigler, Institute of Organic Chemistry and Biochemistry, v.v.i. The Academy of Sciences of the Czech Republic, Flemingovo nam. 2, 166 10 Prague 6 (Czech Republic), Fax: (+420) 220-183-578 www.petrcigler.cz

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Abstract

original image

The back cover picture shows fluorescent, near-IR-emitting diamond nanoparticles coated with a biocompatible polymer interface. The coating is partially peeled off from the particle to reveal the layered structure. First, an ultrathin silica layer is attached to the diamond core. The copolymer chains formed from N-(2-hydroxypropyl)methacrylamide and alkyne-containing methacrylamide monomer are grafted from the silica layer. In their Full Paper on page 21, P. Cigler and co-workers show that thanks to their superior colloidal stability, the nanoparticles can be dissolved in an aqueous buffer of high ionic strength. The coating is translucent, and moreover, it is protein-resistant: it protects the particles against nonspecific protein adsorption.

Cartoon 1.

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