Fast and Sensitive Colorimetric Detection of H2O2 and Glucose: A Strategy Based on Polyoxometalate Clusters (pages 541–544)
Dr. Sen Liu, Jingqi Tian, Lei Wang, Yingwei Zhang, Yonglan Luo, Haiyan Li, Abdullah M. Asiri, Abdulrahman O. Al-Youbi and Prof. Xuping Sun
Article first published online: 30 APR 2012 | DOI: 10.1002/cplu.201200051
Proof-of-concept: A polyoxometalate cluster has been used as a highly effective peroxidase mimetic to catalyze H2O2 oxidation of various peroxidase substrates to give colored solutions, leading to a simple, fast, sensitive, and selective assay for H2O2 with a linear range and detection limit of 1–20 and 0.4 μM. This assay was also used for glucose detection both in buffer solution and diluted serum with a linear range and detection limit of 1–10 and 0.5 μM.