Get access

A Supported Copper Hydroxide as an Efficient, Ligand-free, and Heterogeneous Precatalyst for 1,3-Dipolar Cycloadditions of Organic Azides to Terminal Alkynes

Authors

  • Tatsuyori Katayama,

    1. Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220
    Search for more papers by this author
  • Keigo Kamata Dr.,

    1. Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220
    Search for more papers by this author
  • Kazuya Yamaguchi Dr.,

    1. Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220
    Search for more papers by this author
  • Noritaka Mizuno Prof. Dr.

    1. Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan), Fax: (+81) 3-5841-7220
    Search for more papers by this author

Abstract

original image

Click together: The supported copper hydroxide Cu(OH)x/Al2O3 acts as an efficient heterogeneous precatalyst for the 1,3-dipolar cycloaddition of organic azides to terminal alkynes (click chemistry). The recovered Cu(OH)x/Al2O3 retains its high activity and can be reused.

Ancillary