Electrophilic Activation of Aldehydes “On Water”: A Facile Route to Dipyrromethanes

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Abstract

Shaken … and stirred: Dipyrromethane, an important building block in porphyrin chemistry, can be easily accessed by a reaction performed on water in the absence of Lewis acids. Thus, a variety of substituted dipyrromethanes were prepared in moderate to good yields using a range of aldehydes.

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