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The Phosphine-Catalyzed Wittig Reaction: A New Vista for Olefin Synthesis?



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The design of a catalytic manifold for the Wittig reaction is highlighted. Arsenine-, telluride-, and the recently discovered phosphine-catalyzed processes are discussed and placed into context with the related silyl-Reformatsky process. The specific type of phosphine oxide precatalyst employed is compared with an aza-Wittig process and related transformations.