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Green Synthesis of Dimethyl Isosorbide

Authors

  • Pietro Tundo Prof.,

    1. Consorzio Interuniversitario Nazionale “La Chimica per l'Ambiente” (INCA - Interuniversity Consortium “Chemistry for the Environment“), Via delle Industrie 21/8 30175, Marghera Venice (Italy), Fax:(+39) 0412346650
    2. Ca' Foscari Università di Venezia, Dipartimento Scienze Ambientali, Dorsoduro 2137-30123, Venice (Italy)
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  • Fabio Aricò Dr.,

    1. Consorzio Interuniversitario Nazionale “La Chimica per l'Ambiente” (INCA - Interuniversity Consortium “Chemistry for the Environment“), Via delle Industrie 21/8 30175, Marghera Venice (Italy), Fax:(+39) 0412346650
    2. Ca' Foscari Università di Venezia, Dipartimento Scienze Ambientali, Dorsoduro 2137-30123, Venice (Italy)
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  • Guillaume Gauthier,

    1. École Nationale Supérieure de Chimie de Paris (ENSCP-Chimie ParisTech), 11 rue Pierre et Marie Curie, 75005 Paris (France)
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  • Laura Rossi Prof.,

    1. Instituto de Investigaciones en Fisicoquímica de Córdoba (INFIQC), Facultad de Ciencias Químicas, Departamento de Química Orgánica, Universidad Nacional de Córdoba, Ciudad Universitaria, CP 5000, Córdoba (Argentina)
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  • Anthony E. Rosamilia Dr.,

    1. Consorzio Interuniversitario Nazionale “La Chimica per l'Ambiente” (INCA - Interuniversity Consortium “Chemistry for the Environment“), Via delle Industrie 21/8 30175, Marghera Venice (Italy), Fax:(+39) 0412346650
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  • Hanamanthsa S. Bevinakatti Dr.,

    1. Uniqema Ltd Wilton Centre, Room T425 Wilton, Redcar TS10 4R (United Kingdom)
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  • Robert L. Sievert,

    1. Uniqema Ltd Wilton Centre, Room T425 Wilton, Redcar TS10 4R (United Kingdom)
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  • Christoper P. Newman

    1. Quest International, Ashford, Kent TN24 0 LT (United Kingdom)
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Abstract

original image

A green synthetic approach for dimethyl isosorbide (DMI) with dimethylcarbonate (DMC) in the presence of a base is reported. The easy methylation of isosorbide may be due to its unique structure (which enhances the nucleophilicity of the hydroxyl groups), and to the effect of the hydrogen bonding which increases the reactivity of the molecule towards DMC.

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