Selective Synthesis of N-Alkyl Hydroxylamines by Hydrogenation of Nitroalkanes using Supported Palladium Catalysts



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The selective hydrogenation of nitroalkanes to the corresponding N-alkyl hydroxylamines is achieved at room temperature with excellent yields (up to 98 %), by using common supported palladium catalysts. The reaction temperature is key to the highly selective formation of the hydroxylamines, which proceeds smoothly in a H2 atmosphere without additives. The catalyst can be recycled up to five times.