Advertisement

Conversion of Fructose into 5-(Hydroxymethyl)furfural in Sulfolane

Authors

  • Benjamin R. Caes,

    1. Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706 (USA)
    Search for more papers by this author
  • Prof. Ronald T. Raines

    Corresponding author
    1. Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706 (USA), Fax: (+1) 608-890-2583
    2. Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706 (USA)
    • Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706 (USA), Fax: (+1) 608-890-2583
    Search for more papers by this author

Abstract

original image

Sulfolane, an industrial solvent, allows for the efficient conversion of fructose into 5-(hydroxymethyl)furfural (HMF), a key platform chemical. Yields of ≥90 % are attainable with catalytic HBr in 1 h at 100 °C. The use of an inexpensive catalyst at a low concentration, low temperature, and short reaction time makes the process amenable for large-scale access to HMF.

Ancillary