SEARCH

SEARCH BY CITATION

Keywords:

  • amines;
  • azides;
  • continuous flow;
  • fluorine;
  • oxidation

Abstract

The generation and use of the highly potent oxidising agent HOFMeCN in a controlled single continuous flow process is described. Oxidations of amines and azides to corresponding nitrated systems by using fluorine gas, water and acetonitrile by sequential gas–liquid/liquid–liquid continuous flow procedures are reported.