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Full Paper
Development of New Hydrogenations of Imines and Benign Reductive Hydroaminations: Zinc Triflate as a Catalyst
Article first published online: 9 FEB 2012
DOI: 10.1002/cssc.201100633
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Werkmeister, S., Fleischer, S., Zhou, S., Junge, K. and Beller, M. (2012), Development of New Hydrogenations of Imines and Benign Reductive Hydroaminations: Zinc Triflate as a Catalyst. ChemSusChem, 5: 777–782. doi: 10.1002/cssc.201100633
Publication History
- Issue published online: 30 MAR 2012
- Article first published online: 9 FEB 2012
- Manuscript Revised: 14 NOV 2011
- Manuscript Received: 11 OCT 2011
Funded by
- State of Mecklenburg-Western Pomerania
- BMBF
- DFG
Keywords:
- amines;
- catalysis;
- hydroamination;
- hydrogenation;
- zinc
Abstract
The hydrogenation of imines to amines in the presence of catalytic amounts of zinc triflate has been demonstrated for the first time. In addition, an efficient procedure for the reductive hydroamination of alkynes to amines is presented using zinc triflate as a catalyst precursor. In both protocols a variety of different functional groups are tolerated, and the reactions proceed smoothly in high yields.