The cover image of the January 2011 issue showcases the research of Joanna Webb, Tamara Bolaño, and Brent Gunnoe of the University of Virginia. Their Minireview on page 37 ff. outlines strategies towards the catalytic oxy-functionalization of methane and other hydrocarbons. The development of a catalyst for the controlled conversion of methane to methanol (MTM) would result in a paradigm shift for the chemical industry. Methanol can be used in fuel cells to generate electricity, can be converted to diesel fuel or gasoline, and can be used as a precursor to ethylene or propylene. Thus, the MTM process would allow natural gas to be used on a scale that is not currently conceivable.