Full Paper

Metal-Free Aerobic Alcohol Oxidation: Intensification under Three-Phase Flow Conditions

  1. Christof Aellig,
  2. David Scholz,
  3. Prof. Dr. Ive Hermans*

Article first published online: 23 AUG 2012

DOI: 10.1002/cssc.201200438

Issue

ChemSusChem

ChemSusChem

Volume 5, Issue 9, pages 1732–1736, September 2012

Additional Information

How to Cite

Aellig, C., Scholz, D. and Hermans, I. (2012), Metal-Free Aerobic Alcohol Oxidation: Intensification under Three-Phase Flow Conditions. ChemSusChem, 5: 1732–1736. doi: 10.1002/cssc.201200438

Author Information

  1. Institute for Chemical and Bioengineering, ETH Zurich, Wolfgang-Pauli-Strasse 10, 8093 Zurich (Switzerland), Fax: (+41) 44-633-42-58

*Institute for Chemical and Bioengineering, ETH Zurich, Wolfgang-Pauli-Strasse 10, 8093 Zurich (Switzerland), Fax: (+41) 44-633-42-58

Publication History

  1. Issue published online: 5 SEP 2012
  2. Article first published online: 23 AUG 2012
  3. Manuscript Received: 26 JUN 2012

Funded by

  • ETH Zurich. Grant Number: 18 09-2

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (297K)

Keywords:

  • alcohols;
  • flow chemistry;
  • metal-free chemistry;
  • oxidation;
  • process intensification

Abstract

The selective oxidation of alcohols is a pivotal transformation within industrial and synthetic chemistry. In this contribution we use O2 as terminal oxidant and (H)NOx species as oxygen shuttle in order to mediate the oxidation of primary and secondary alcohols under the influence of a solid acid catalyst. Process optimization and intensification through the use of a continuous three-phase flow reactor is demonstrated. Space–time yields were found to increase by two orders of magnitude with respect to batch experiments, along with additional gains in selectivity and a decrease of N2O formation.

View Full Article (HTML) Get PDF (297K)