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Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry

Authors

  • Prof. Dr. Volker Hessel,

    Corresponding author
    1. Department of Chemical Engineering and Chemistry, Micro Flow Chemistry and Process Technology, Eindhoven University of Technology, PO BOX 513, 5600 MB Eindhoven (The Netherlands)
    • Department of Chemical Engineering and Chemistry, Micro Flow Chemistry and Process Technology, Eindhoven University of Technology, PO BOX 513, 5600 MB Eindhoven (The Netherlands)
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  • Dr. Dana Kralisch,

    1. Institute of Technical Chemistry and Environmental Chemistry, Friedrich-Schiller-University Jena, Lessingstr. 12, 07743 Jena (Germany)
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  • Prof. Dr. Norbert Kockmann,

    1. Biochemical and Chemical Engineering, Equipment Design, Technical University Dortmund, Emil-Figge-Str. 68, 44227 Dortmund (Germany)
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  • Dr. Timothy Noël,

    1. Department of Chemical Engineering and Chemistry, Micro Flow Chemistry and Process Technology, Eindhoven University of Technology, PO BOX 513, 5600 MB Eindhoven (The Netherlands)
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  • Dr. Qi Wang

    1. Department of Chemical Engineering and Chemistry, Micro Flow Chemistry and Process Technology, Eindhoven University of Technology, PO BOX 513, 5600 MB Eindhoven (The Netherlands)
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Abstract

Novel Process Windows make use of process conditions that are far from conventional practices. This involves the use of high temperatures, high pressures, high concentrations (solvent-free), new chemical transformations, explosive conditions, and process simplification and integration to boost synthetic chemistry on both the laboratory and production scale. Such harsh reaction conditions can be safely reached in microstructured reactors due to their excellent transport intensification properties. This Review discusses the different routes towards Novel Process Windows and provides several examples for each route grouped into different classes of chemical and process-design intensification.

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