The front cover shows a flow system that operates with a highly effective immobilized peptidic catalyst, reported by Helma Wennemers and co-workers from the ETH Zürich, Switzerland on page 242. More than 600 turnovers and high stereoselectivities are achieved on a scale of >450 mmol (>100 g), without a significant drop of the activity or stereoselectivity of the immobilized peptidic catalyst. This high efficiency and sustainability of a flow system is unprecedented in the very active field of enamine catalysis and opens the way for more practical applications.
If you can't find a tool you're looking for, please click the link at the top of the page to "Go to old article view". Alternatively, view our Knowledge Base articles for additional help. Your feedback is important to us, so please let us know if you have comments or ideas for improvement.