Cover Picture: Enamine Catalysis in Flow with an Immobilized Peptidic Catalyst (ChemSusChem 2/2013)



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The front cover shows a flow system that operates with a highly effective immobilized peptidic catalyst, reported by Helma Wennemers and co-workers from the ETH Zürich, Switzerland on page 242. More than 600 turnovers and high stereoselectivities are achieved on a scale of >450 mmol (>100 g), without a significant drop of the activity or stereoselectivity of the immobilized peptidic catalyst. This high efficiency and sustainability of a flow system is unprecedented in the very active field of enamine catalysis and opens the way for more practical applications.

Cartoon 1.