Bio-Based Nitriles from the Heterogeneously Catalyzed Oxidative Decarboxylation of Amino Acids (pages 345–352)
Laurens Claes, Roman Matthessen, Dr. Ine Rombouts, Ivo Stassen, Trees De Baerdemaeker, Prof. Diederik Depla, Prof. Jan A. Delcour, Dr. Bert Lagrain and Prof. Dirk E. De Vos
Article first published online: 3 DEC 2014 | DOI: 10.1002/cssc.201402801
Going the extra nitrile: A catalytic system that consists of a tungstate-exchanged layered double hydroxide and a bromide salt is developed for the oxidative decarboxylation of amino acids under mild conditions using H2O2 as a green oxidant. Several functional groups are tolerated, and the nitrile selectivity is often 99 %. This strategy offers opportunities for protein-rich biomass valorization.