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LITERATURE CITED

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    Cote RJ, Shi S-R, Beattie EJ, Makarewicz K, Chaiwun B, Yang C, Groshen S, Taylor CR. Automated detection of occult bone marrow micrometastases in patients with operable lung carcinoma [abstract]. Proc ASCO 1997; 16: 1645.
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    Cote RJ, Rosen PP, Lesser LM, Old LJ, Osborne M. Prediction of early relapse in patients with operable breast cancer by detection of occult bone marrow micrometastases. J Clin Oncol 1991; 9: 17491756.
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    Schlimok G, Funke I, Pantel K, Strobel F, Lindemann F, Witte J, Riethmüller G. Micrometastatic tumor cells in bone marrow of patients with gastric cancer: methodological aspects of detection and prognostic significance. Eur J Cancer 1991; 27: 14611465.
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    Dearnaley DP, Ormerod MG, Sloane JP. Micrometastases in breast cancer: long-term follow-up of the first patient cohort. Eur J Cancer 1991; 27: 236239.
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    Moss TJ, Reynolds CP, Sather HN, Romansky SG, Hammond GD, Seeger RC. Prognostic value of immunocytologic detection of bone marrow metastases in neuroblastoma N Engl J Med 1991;24: 219226.
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    Schlimok G, Lindemann F, Holzmann K, Witte J, Renner D, Riethmüller G. Prognostic significance of disseminated tumor cells detected in bone marrow of patients with breast and colorectal cancer: a multivariate analysis. Proc Am Soc Clin Oncol 1992; 11: 102.
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    Lindemann F, Schlimok G, Dirschedl P, Witte J, Riethmüller G. Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients. Lancet 1992; 340: 685689.
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    Harbeck N, Untch M, Pache L, Eiermann W. Tumor cell detection in the bone marrow of breast cancer patients at primary therapy: results of a 3-year median follow-up. Br J Cancer 1994; 69: 566571.
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    Cote RJ, Beattie EJ, Chaiwun B, Shi S-R, Harvey J, Chen S-C, Sherrod AE, Groshen S, Taylor CR. Detection of occult bone marrow micrometastases in patients with operable lung carcinoma. Ann Surg 1995; 222: 415425.
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    Diel IJ, Kaufmann M, Costa SD, Holle R, von Minckwitz G, Solomayer EF, Kaul S, Bastert G. Micrometastatic breast cancer cells in bone marrow at primary surgery: prognostic value in comparison with nodal status. J Nat Cancer Inst 1996; 88: 16521658.
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    Pantel K, Izbicki J, Passlick B, Angstwurm M, Häussinger K, Thetter O, Riethmüller G. Frequency and prognostic significance of isolated tumor cells in bone marrow of patients with non-small-cell lung cancer without overt metastases. Lancet 1996; 347: 649653.
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    Jauch KW, Heiss MM, Gruetzner U, Funke I, Pantel K, Babic R, Eissner HJ, Riethmüller G, Schildberg FW. Prognostic significance of bone marrow micrometastases in patients with gastric cancer. J Clin Oncol 1996; 14: 18101817.
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    Roder JD, Thorban S, Pantel K, Siewert JR. Micrometastases in bone marrow: prognostic indicators for pancreatic cancer. World J Surg 1999; 23: 888891.
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    Mansi JL, Gogas H, Bliss JM, Gazet JC, Berger U, Coombes RC. Outcome of primary-breast-cancer patients with micrometastases: a long-term follow-up study. Lancet 1999; 354: 197202.
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    Thorban S, Rosenberg R, Busch R, Roder RJ. Epithelial cells in bone marrow of esophageal cancer patients: a significant prognostic factor in multivariate analysis Br J Cancer 2000;83: 3539.
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    Janni W, Gastroph S, Hepp F, Kentenich C, Rjosk D, Schindlbeck C, Dimpfl T, Sommer H, Braun S. Prognostic significance of an increased number of micrometastatic tumor cells in the bone marrow of patients with first recurrence of breast carcinoma. Cancer 2000; 88: 22522259.
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    Braun S, Pantel K, Müller P, Janni W, Hepp F, Kentenich CRM, Gastroph S, Wischnik A, Dimplf T, Kindermann G, Riethmüller G, Schlimok G. Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II or III breast cancer. N Engl J Med 2000; 342: 525533.
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    Borgen E, Naume B, Nesland JM, Kvalheim G, Beiske K, Fodstad Ø, Diel I, Solomayer E-F, Theocharous P, Coombes RC, Smith BM, Wunder E, Marolleau J-P, Garcia J, Pantel K. Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. Establishment of objective criteria for the evaluation of immunostained cells. Cytotherapy 1999; 1: 377388.
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    Pantel K, Cote R, Fodstad Ø. Detection and clinical importance of micrometastatic disease. J Nat Cancer Inst 1999; 91: 11131124.
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    Pantel K, von Knebel Doeberitz M. Detection and clinical relevance of micrometastatic cancer cells. Curr Opin Oncol 2000; 12: 95101.
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    Müller P, Schlimok G. Bone marrow micrometastases of epithelial tumors: detection and clinical relevance J Cancer Res Clin Oncol 2000;126: 607618.
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    Pantel K, Schlimok G, Angstwurm M, Weckermann D, Schmaus W, Gath H, Passlick B, Izbicki JR, Riethmüller G. Methodological analysis of immunocytochemical screening for disseminated epithelial tumor cells in bone marrow. J Hematotherapy 1994; 3: 165173.
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    Naume B, Borgen E, Nesland JM, Beiske K, Gilen E, Renolen A, Ravnås G, Qvist H, Kåresen K, Kvalheim G. Increased sensitivity for detection of micrometastases in bone-marrow/peripheral-blood stem-cell products from breast-cancer patients by negative immunomagnetic separation. Int J Cancer 1998; 78: 556560.