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LITERATURE CITED

  • 1
    Moretta A,Bottino C,Mingari MC,Biassoni R,Moretta L. What is a natural killer cell? Nat Immunol 2002; 3: 68.
  • 2
    Braud VM,Allan DS,O'Callaghan CA,.Soderstrom K,D'Andrea A,Ogg GS,Lazetic S,Young NT,Bell JI,Phillips JH,Lanier LL,McMichael AJ. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 1998; 391: 740743.
  • 3
    Bennett IM,Zatsepina O,Zamai L,Azzoni L,Mikheeva T,Perussia B. Definition of a natural killer NKR-P1A+/CD56/CD16 functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12. J Exp Med 1996; 184: 18451856.
  • 4
    Sivori S,Falco M,Marcenaro E,Parolini S,Biassoni R,Bottino C,Moretta L,Moretta A. Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation. Proc Natl Acad Sci USA 2002; 99: 45264531.
  • 5
    Cooper MA,Fehniger TA,Caligiuri MA. The biology of human natural killer-cell subsets. Trends Immunol 2001; 22: 633640.
  • 6
    Ferlazzo G,Thomas D,Lin SL,Goodman K,Morandi B,Muller WA,Moretta A,Münz C. The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic. J Immunol 2004; 172: 14551462.
  • 7
    Mrozek E,Anderson P,Caligiuri MA. Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells. Blood 1996; 87: 26322640.
  • 8
    Yu H,Fehniger TA,Fuchshuber P,Thiel KS,Vivier E,Carson WE,Caligiuri MA. Flt3 ligand promotes the generation of a distinct CD34(+) human natural killer cell progenitor that responds to interleukin-15. Blood 1998; 92: 36473657.
  • 9
    Farag SS,Caligiuri MA. Human natural killer cell development and biology. Blood Rev 2006; 20: 123137.
  • 10
    Freud AG,Becknell B,Roychowdhury S,Mao HC,Ferketich AK,Nuovo GJ,Hughes TL,Marburger TB,Sung J,Baiocchi RA,Guimond M,Caligiuri MA. A human CD34(+) subset resides in lymph nodes and differentiates into CD56bright natural killer cells. Immunity 2005; 22: 295304.
  • 11
    Zamai L,Ahmad M,Bennett IM,Azzoni L,Alnemri ES,Perussia B. Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells. J Exp Med 1998; 188: 23752380.
  • 12
    Loza MJ,Zamai L,Azzoni L,Rosati E,Perussia B. Expression of type 1 (interferon gamma) and type 2 (interleukin-13, interleukin-5) cytokines at distinct stages of natural killer cell differentiation from progenitor cells. Blood 2002; 99: 12731281.
  • 13
    Freud AG,Yokohama A,Becknell B,Lee MT,Mao HC,Ferketich AK,Caligiuri MA. Evidence for discrete stages of human natural killer cell differentiation in vivo. J Exp Med 2006; 203: 10331043.
  • 14
    Grzywacz B,Kataria N,Sikora M,Oostendorp RA,Dzierzak EA,Blazar BR,Miller JS,Verneris MR. Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells. Blood 2006; 108: 38243833.
  • 15
    Medvedev AE,Johnsen AC,Haux J,Steinkjer B,Egeberg K,Lynch DH,Sundan A,Espevik T. Regulation of Fas and Fas-ligand expression in NK cells by cytokines and the involvement of Fas-ligand in NK/LAK cell-mediated cytotoxicity. Cytokine 1997; 9: 394404.
  • 16
    Johnsen AC,Haux J,Steinkjer B,Nonstad U,Egeberg K,Sundan A,Ashkenazi A,Espevik T. Regulation of APO-2 ligand/trail expression in NK cells-involvement in NK cell-mediated cytotoxicity. Cytokine 1999; 11: 664672.
  • 17
    Mirandola P,Ponti C,Gobbi G,Sponzilli I,Vaccarezza M,Cocco L,Zauli G,Secchiero P,Manzoli FA,Vitale M. Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity. Blood 2004; 104: 24182424.
  • 18
    Robertson MJ,Caligiuri MA,Manley TJ,Levine H,Ritz J. Human natural killer cell adhesion molecules. Differential expression after activation and participation in cytolysis. J Immunol 1990; 145: 31943201.
  • 19
    Zamai L,Ponti C,Mirandola P,Gobbi G,Papa S,Galeotti L,Cocco L,Vitale M. Natural killer cells and cancer. J Immunol 2007; 178: 40114016.
  • 20
    Raulet DH,Vance RE,McMahon CW. Regulation of the natural killer cell receptor repertoire. Annu Rev Immunol 2001; 19: 291330.
  • 21
    Raulet DH,Vance RE. Self-tolerance of natural killer cells. Nat Rev Immunol 2006; 6: 520531.
  • 22
    Frey M,Packianathan NB,Fehniger TA,Ross ME,Wang WC,Stewar CC,Caligiuri MA,Evans SS. Differential expression and function of L-selectin on CD56bright and CD56dim natural killer cell subsets. J Immunol 1998; 161: 400408.
  • 23
    Freud AG,Caligiuri MA. Human natural killer cell development. Immunol Rev 2006; 214: 5672.
  • 24
    Shilling HG,McQueen KL,Cheng NW,Shizuru JA,Negrin RS,Parham P. Reconstitution of NK cell receptor repertoire following HLA-matched hematopoietic cell transplantation. Blood 2003; 101: 37303740.
  • 25
    Barao I,Hudig D,Ascensao JL. IL-15-mediated induction of LFA-1 is a late step required for cytotoxic differentiation of human NK cells from CD34+Lin bone marrow cells. J Immunol 2003; 171: 683690.
  • 26
    Kim S,Iizuka K,Kang HS,Dokun A,French AR,Greco S,Yokoyama WM. In vivo developmental stages in murine natural killer cell maturation. Nat Immunol 2002; 3: 523528.
  • 27
    Takahashi E,Kuranaga N,Satoh K,Habu Y,Shinomiya N,Asano T,Seki S,Hayakawa M. Induction of CD16+ CD56bright NK cells with antitumour cytotoxicity not only from CD16− CD56bright NK Cells but also from CD16− CD56dim NK cells. Scand J Immunol 2007; 65: 126138.
  • 28
    Loza MJ,Perussia B. Final steps of natural killer cell maturation: a model for type 1-type 2 differentiation? Nat Immunol 2001; 2: 917924.
  • 29
    Cooper MA,Fehniger TA,Turner SC,Chen KS,Ghaheri BA,Ghayur T,Carson WE,Caligiuri MA. Human natural killer cells: A unique innate immunoregulatory role for the CD56(bright) subset. Blood 2001; 97: 31463151.
  • 30
    Miller JS,McCullar V. Human natural killer cells with polyclonal lectin and immunoglobulinlike receptors develop from single hematopoietic stem cells with preferential expression of NKG2A and KIR2DL2/L3/S2. Blood 2001; 98: 705713.
  • 31
    Carayol G,Robin C,Bourhis JH,Bennaceur-Griscelli A,Chouaib S,Coulombel L,Caignard A. NK cells differentiated from bone marrow, cord blood and peripheral blood stem cells exhibit similar phenotype and functions. Eur J Immunol 1998; 28: 19912002.