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LITERATURE CITED

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    Warnatz K,Denz A,Drager R,Braun M,Groth C,Wolff-Vorbeck G,Eibel H,Schlesier M,Peter HH. Severe deficiency of switched memory B cells (CD27(+)IgM(−)IgD(−)) in subgroups of patients with common variable immunodeficiency: A new approach to classify a heterogeneous disease. Blood 2002; 99: 15441551.
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    Piqueras B,Lavenu-Bombled C,Galicier L,Bergeron-Van Der Cruyssen F,Mouthon L,Chevret S,Debre P,Schmitt C,Oksenhendler E. Common variable immunodeficiency patient classification based on impaired B cell memory differentiation correlates with clinical aspects. J Clin Immunol 2003; 23: 385400.
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    Vlkova M,Thon V,Sarfyova M,Blaha L,Svobodnik A,Lokaj J,Litzman J. Age dependency and mutual relations in T and B lymphocyte abnormalities in common variable immunodeficiency patients. Clin Exp Immunol 2006; 143: 373379.
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    Wehr C,Kivioja T,Schmitt C,Ferry B,Witte T,Eren E,Vlkova M,Hernandez M,Detkova D,Bos PR, Poerksen G, von Bernuth H, Baumann U, Goldacker S, Gutenberger S, Schlesier M, Bergeron-van der Cruyssen F, Le Garff M, Debre P, Jacobs R, Jones J, Bateman E, Litzman J, van Hagen PM, Plebani A, Schmidt RE, Thon V, Quinti I, Espanol T, Webster AD, Chapel H, Vihinen M, Oksenhendler E, Peter HH, Warnatz K. The EUROclass trial: Defining subgroups in common variable immunodeficiency. Blood 2008; 111: 7785.
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    Roederer M,Moore W,Treister A,Hardy RR,Herzenberg LA. Probability binning comparison: A metric for quantitating multivariate distribution differences. Cytometry 2001; 45: 4755.
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    Langfelder P,Zhang B,Horvath S. Defining clusters from a hierarchical cluster tree: The dynamic tree cut package for R. Bioinformatics 2008; 24: 719720.
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    Saeed AI,Sharov V,White J,Li J,Liang W,Bhagabati N,Braisted J,Klapa M,Currier T,Thiagarajan M, Sturn A, Snuffin M, Rezantsev A, Popov D, Ryltsov A, Kostukovich E, Borisovsky I, Liu Z, Vinsavich A, Trush V, Quackenbush J. TM4: A free, open-source system for microarray data management and analysis. Biotechniques 2003; 34: 374378.
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    Avery DT,Ellyard JI,Mackay F,Corcoran LM,Hodgkin PD,Tangye SG. Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage. J Immunol 2005; 174: 40344042.
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    Cuss AK,Avery DT,Cannons JL,Yu LJ,Nichols KE,Shaw PJ,Tangye SG. Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity. J Immunol 2006; 176: 15061516.
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    Klein U,Rajewsky K,Kuppers R. Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J Exp Med 1998; 188: 16791689.
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    Warnatz K,Schlesier M. Flowcytometric phenotyping of common variable immunodeficiency. Cytometry Part B Clin Cytom 2008; 74B: 261271.
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    Weller S,Braun MC,Tan BK,Rosenwald A,Cordier C,Conley ME,Plebani A,Kumararatne DS,Bonnet D,Tournilhac O, Tchernia G, Steiniger B, Staudt LM, Casanova JL, Reynaud CA, Weill JC. Human blood IgM “memory” B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. Blood 2004; 104: 36473654.
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    Pedreira CE,Costa ES,Almeida J,Fernandez C,Quijano S,Flores J,Barrena S,Lecrevisse Q,Van Dongen JJ,Orfao A. A probabilistic approach for the evaluation of minimal residual disease by multiparameter flow cytometry in leukemic B-cell chronic lymphoproliferative disorders. Cytometry Part A 2008; 73A: 11411150.
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    Steinbrich-Zollner M,Grun JR,Kaiser T,Biesen R,Raba K,Wu P,Thiel A,Rudwaleit M,Sieper J,Burmester GR, Radbruch A, Grutzkau A. From transcriptome to cytome: Integrating cytometric profiling, multivariate cluster, and prediction analyses for a phenotypical classification of inflammatory diseases. Cytometry Part A 2008; 73A: 333340.