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Abstract

The cover image shows enzymatic signal amplification. Green dye molecules are observed passing through an antibody-conjugated ring, representing their oxidation into reactive free radicals by horseradish peroxidase, followed by covalent deposition onto a nearby protein. Image courtesy of Peter Krutzik, Matt Clutter and Garry Nolan and modified by Bärbel Beran [www.beran-design.de].