Gene expression varies significantly between individual cells when moving through the cell cycle. As an example, tenascin-C promoter expression increases in most cultured T3T cells but decreases in some. These individual differences can only be revealed by quantitative, automated time-lapse microscopy in combination with automated image recognition and analysis. (Read more in Halter et al. in this issue.)
Cover design by Bärbel Beran [www.beran-design.de].