SEARCH

SEARCH BY CITATION

Literature Cited

  • 1
    Garrett TPJ, McKern NM, Lou MZ, Elleman TC, Adams TE, Lovrecz GO, Zhu HJ, Walker F, Frenkel MJ, Hoyne PA, et al. Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor α. Cell 2002;110:763773.
  • 2
    Ogiso H, Ishitani R, Nureki O, Fukai S, Yamanaka M, Kim JH, Saito K, Sakamoto A, Inoue M, Shirouzu M, et al. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell 2002;110:775787.
  • 3
    Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol Cell 2003;11:507517.
  • 4
    Lemmon MA, Bu ZM, Ladbury JE, Zhou M, Pinchasi D, Lax I, Engelman DM, Schlessinger J. Two EGF molecules contribute additively to stabilization of the EGFR dimer. EMBO J 1997;16:281294.
  • 5
    Garrett TPJ, McKern NM, Lou MZ, Elleman TC, Adams TE, Lovrecz GO, Kofler M, Jorissen RN, Nice EC, Burgess AW, et al. The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors. Mol Cell 2003;11:495505.
  • 6
    Ozcan F, Klein P, Lemmon MA, Lax I, Schlessinger J. On the nature of low- and high-affinity EGF receptors on living cells. Proc Natl Acad Sci USA 2006;103:57355740.
  • 7
    Schmitz KR, Ferguson KM. Interaction of antibodies with ErbB receptor extracellular regions. Exp Cell Res 2009;315:659670.
  • 8
    Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell 2005;7:301311.
  • 9
    Schmiedel J, Blaukat A, Li S, Knochel T, Ferguson KM. Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell 2008;13:365373.
  • 10
    Lemmon MA. Ligand-induced ErbB receptor dimerization. Exp Cell Res 2009;315:638648.
  • 11
    Kozer N, Henderson C, Jackson JT, Nice EC, Burgess AW, Clayton AH. Evidence for extended YFP-EGFR dimers in the absence of ligand on the surface of living cells. Phys Biol 2011;8:066002.
  • 12
    George N, Pick H, Vogel H, Johnsson N, Johnsson K. Specific labeling of cell surface proteins with chemically diverse compounds. J Am Chem Soc 2004;126:8896.
  • 13
    Vivero-Pol L, George N, Krumm H, Johnsson K, Johnsson N. Muticolor imaging of cell surface membrane proteins. J Am Chem Soc 2005;127:1277012771.
  • 14
    Kucherak OA, Oncul S, Darwich Z, Yushchenko DA, Arntz Y, Didier P, Mely Y, Klymchenko AS. Switchable nile red-based probe for cholesterol and lipid order at the outer leaflet of biomembranes. J Am Chem Soc 2010;132:49074916..
  • 15
    Ferguson KM. Active and inactive conformations of the epidermal growth factor receptor. Biochem Soc Trans 2004;32:742745.
  • 16
    The PyMOL Molecular Graphics System. 1.5.0.4: Schrödinger, LLC.
  • 17
    Lu C, Mi L, Grey M, Zhu J, Graef E, Yokoyama S, Springer T. Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor. Mol Cell Biol 2010;30:5432.
  • 18
    Ponder J, Case D. Force fields for protein simulations. Adv Prot Chem 2003;66:2785.
  • 19
    Hess B, Kutzner C, van der Spoel D, Lindahl E. GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation. J Chem Theory Comp 2008;4:435447.
  • 20
    George N. A new method for protein labeling with small molecules based on acyl carrier protein. [Doc. Sci.]. Lausanne: École Polytechnique Fédérale de Lausanne; 2006. 149 p.
  • 21
    Jares-Erijman EA, Jovin TM. Imaging molecular interactions in living cells by FRET microscopy. Curr Opin Chem Biol 2006;10:18.
  • 22
    Bastiaens P, de Beus A, Lacker M, Somerharju P, Vauhkonen M, Eisinger J. Resonance energy transfer from a cylindrical distribution of donors to a plane of acceptors. Location of apo-B100 protein on the human low-density lipoprotein particle. Biophys J 1990;58:665675.
  • 23
    Fung BK, Stryer L. Surface density determination in membranes by fluorescence energy transfer. Biochemistry 1978;17:52415248.
  • 24
    Kim Y, Prestegard J. Refinement of the NMR structures for acyl carrier protein with scalar coupling data. Proteins 1990;8:377.
  • 25
    Darwich Z, Klymchenko A, Kucherak O, Richert L, Mély Y. Detection of apoptosis through the lipid order of the outer plasma membrane leaflet. Biochem Biophys Acta-Biomembr 2012;1818:30493054.
  • 26
    Duncan RR, Bergmann A, Cousin MA, Apps DK, Shipston MJ. Multi-dimensional time-correlated single photon counting (TCSPC) fluorescence lifetime imaging microscopy (FLIM) to detect FRET in cells. J Microsc 2004;215:112.
  • 27
    Chia TH, Williamson A, Spencer DD, Levene MJ. Multiphoton fluorescence lifetime imaging of intrinsic fluorescence in human and rat brain tissue reveals spatially distinct NADH binding. Opt Expr 2008;16:42374249.
  • 28
    Bessman NJ, Lemmon MA. Finding the missing links in EGFR. Nat Struct Mol Biol 2012;19:13.
  • 29
    Sengupta P, Holowka D, Baird B. Fluorescence resonance energy transfer between lipid probes detects nanoscopic heterogeneity in the plasma membrane of live cells. Biophys J 2007;92:35643574.
  • 30
    Ferguson KM. Structure-based view of epidermal growth factor receptor regulation. Annu Rev Biophys 2008;37:353373.
  • 31
    Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, Wemmer DE, Zhang X, Kuriyan J. Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell 2009;137:12931307.
  • 32
    Alvarado D, Klein DE, Lemmon MA. Structural basis for negative cooperativity in growth factor binding to an EGF receptor. Cell 2010;142:568579.
  • 33
    Martin-Fernandez M, Clarke DT, Tobin MJ, Jones SV, Jones GR. Preformed oligomeric epidermal growth factor receptors undergo an ectodomain structure change during signaling. Biophys J 2002;82:24152427.
  • 34
    Roberts SK, Tynan CJ, Winn M, Martin-Fernandez ML. Investigating extracellular in situ EGFR structure and conformational changes using FRET microscopy. Biochem Soc Trans 2012;40:189194.
  • 35
    Tynan CJ, Roberts SK, Rolfe DJ, Clarke DT, Loeffler HH, Kastner J, Winn MD, Parker PJ, Martin-Fernandez ML. Human epidermal growth factor receptor (EGFR) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry. Mol Cell Biol 2011;31:22412252.
  • 36
    Zacharias DA, Violin JD, Newton AC, Tsien RY. Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science 2002;296:913916.
  • 37
    Clayton AH, Walker F, Orchard SG, Henderson C, Fuchs D, Nice EC, Burgess AW. Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis. J Biol Chem 2005;280:3039230399.
  • 38
    Saffarian S, Li Y, Elson EL, Pike LJ. Oligomerization of the EGF receptor investigated by live cell fluorescence intensity distribution analysis. Biophys J 2007;93:10211031.
  • 39
    Nagy P, Claus J, Jovin TM, Arndt-Jovin DJ. Distribution of resting and ligand-bound ErbB1 and ErbB2 receptor tyrosine kinases in living cells using Number and Brightness analysis. Proc Natl Acad Sci USA 2010;107:1652416529.
  • 40
    Low-Nam ST, Lidke KA, Cutler PJ, Roovers RC, van Bergen en Henegouwen PMP, Wilson BS, Lidke DS. ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding. Nat Struct Mol Biol 2011;18:12441249.
  • 41
    Lidke DS, Lidke KA, Rieger B, Jovin TM, Arndt-Jovin DJ. Reaching out for signals: Filopodia sense EGF and respond by directed retrograde transport of activated receptors. J Cell Biol 2005;170:619626.
  • 42
    Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I. Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature 2010;464:783787.
  • 43
    Coskun U, Grzybek M, Drechsel D, Simons K. Regulation of human EGF receptor by lipids. Proc Natl Acad Sci USA 2011;108:90449048.
  • 44
    Schneider MR, Wolf E. The epidermal growth factor receptor ligands at a glance. J Cell Physiol 2009;218:460466.
  • 45
    Offterdinger M, Bastiaens PI. Prolonged EGFR signaling by ERBB2-mediated sequestration at the plasma membrane. Traffic 2008;9:147155.
  • 46
    Offterdinger M, Georget V, Girod A, Bastiaens PI. Imaging phosphorylation dynamics of the epidermal growth factor receptor. J Biol Chem 2004;279:3697236981.
  • 47
    Arteaga CL. ERBB receptors in cancer: Signaling from the inside. Breast Cancer Res 2011;13:304.
  • 48
    Al Dayel F. EGFR mutation testing in non-small cell lung cancer (NSCLC). J Infect Publ Health 2012;5 (Suppl 1):S31S34.
  • 49
    Huang PH, Mukasa A, Bonavia R, Flynn RA, Brewer ZE, Cavenee WK, Furnari FB, White FM. Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proc Natl Acad Sci USA 2007;104:1286712872.
  • 50
    Gan HK, Kaye AH, Luwor RB. The EGFRvIII variant in glioblastoma multiforme. J Clin Neurosci 2009;16:748754.
  • 51
    Arkhipov A, Shan Y, Das R, Endres NF, Eastwood MP, Wemmer DE, Kuriyan J, Shaw DE. Architecture and membrane interactions of the EGF receptor. Cell 2013;152:557569.