On the cover: Multiphoton in vivo imaging reveals intricate design of lymph nodes with a detailed map of origin and migratory routes of memory B cells and plasma cells. White arrows point at BLIMP-1+ plasma cells migrating away from germinal centers (GCs) towards their preprogrammed fate. Roth et al. review the factors responsible for differentiation, localization and migration of plasma cells in this issue.
Cover design by Bärbel Beran [www.beran-design.de].