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LITERATURE CITED

  • 1
    Maury S,Mary JY,Rabian C,Schwarzinger M, Toubert A, Scieux C, Carmagnat M, Esperou H, Ribaud P, Devergie A, Guardiola P, Vexiau P, Charron D, Gluckman E,Socié G. Prolonged immune deficiency following allogeneic stem cell transplantation: Risk factors and complications in adult patients. Br J Haematol 2001; 115: 630641.
  • 2
    Storek J,Gooley T,Witherspoon RP,Sullivan KM,Storb R. Infectious morbidity in long-term survivors of allogeneic marrow transplantation is associated with low CD4 T cell counts. Am J Hematol 1997; 54: 131138.
  • 3
    Meyers JD,Flournoy N,Thomas ED. Risk factors for cytomegalovirus infection after human marrow transplantation. J Infect Dis 1986; 153: 478488.
  • 4
    Boeckh M,Nichols WG,Papanicolaou G,Rubin R,Wingard JR,Zaia J. Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies. Biol Blood Marrow Transplant 2003; 9: 543558.
  • 5
    Hebart H,Einsele H. Clinical aspects of CMV infection after stem cell transplantation. Hum Immunol 2004; 65: 432436.
  • 6
    Zaia JA. Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation. Clin Infect Dis 2002; 35: 9991004.
  • 7
    Ljungman P. Would monitoring CMV immune responses allow improved control of CMV in stem cell transplant patients. J Clin Virol 2006; 35: 493495.
  • 8
    Kern F,LiPira G,Gratama JW,Manca F,Roederer M. Measuring Ag-specific immune responses: Understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer. Trends Immunol 2005; 26: 477484.
  • 9
    Maecker HT,Dunn HS,Suni MA,Khatamazas E, Pitcher CJ, Bunde T, Persaud N, Trigona W, Fu TM, Sinclair E, Bredt BM, McCune JM, Maino VC, Kern F, Picker LJ. Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. J Immunol Methods 2001; 255: 2740.
  • 10
    Kern F,Faulhaber N,Frommel C,Khatamzas E, Prosch S, Schonemann C, Kretzschmar I,Volkmer-Engert R, Volk HD, Reinke P. Analysis of CD8 T cell reactivity to cytomegalovirus using protein-spanning pools of overlapping pentadecapeptides. Eur J Immunol 2000; 30: 16761682.
  • 11
    Bunde T,Kirchner A,Hoffmeister B, Habedank D, Hetzer R, Cherepnev G, Proesch S, Reinke P, Volk HD, Lehmkuhl H, Kern F. Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells. J Exp Med 2005; 201: 10311036.
  • 12
    Cornelissen JJ,van der Holt B,Petersen EJ, Videlov L, Russel CA, Hoglund M, Maertens J, Schouten HC, Braakman E, Steijaert MM, Zijlmans MJ,Slaper-Corenbach I, Boogaerts MA, Lowenberg B, Verdonck LF. A randomized multicenter comparison of CD34(+)-selected progenitor cells from blood vs from bone marrow in recipients of HLA-identical allogeneic transplants for hematological malignancies. Exp Hematol 2003; 31: 855864.
  • 13
    Broers AE,van der Holt R,van Esser JW, Gratama JW,Henzen-Logmans S,Kuenen-Boumeester V, Lowenberg B, Cornelisssen JJ. Increased transplant-related morbidity and mortality in CMV-seropositive patients despite highly effective prevention of CMV disease after allogeneic T-cell-depleted stem cell transplantation. Blood 2000; 95: 22402245.
  • 14
    Glucksberg H,Storb R,Fefer A,Buckner CD,Neiman PE,Clift RA,Lerner KG,Thomas ED. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HLA-matched sibling donors. Transplantation 1974; 18: 295304.
  • 15
    van Doornum GJ,Guldemeester J,Osterhaus AD,Niesters HG. Diagnosing herpesvirus infections by real-time amplification and rapid culture. J Clin Microbiol 2003; 41: 576580.
  • 16
    Gratama JW,van Esser JW,Lamers CH,Tournay C, Lowenberg B, Bolhuis RL, Cornelissen JJ. Tetramer-based quantification of cytomegalovirus (CMV)-specific CD8+ T lymphocytes in T-cell-depleted stem cell grafts and after transplantation may identify patients at risk for progressive CMV infection. Blood 2001; 98: 13581364.
  • 17
    Solbach W. Tumor-promoting phorbol esters selectively abrogate the expression of the T4 differentiation antigen expressed on normal and malignant (Sézary) T helper lymphocytes. J Exp Med 1982; 156: 12501255.
  • 18
    Dwyer J,Feinleib M. Introduction to statistical models for longitudinal observation. In: DwyerJ, FeinleibM, LippertP, HoffmeisterH, editors. Statistical models for longitudinal studies of health. New York: Oxford University Press; 1992. p 348.
  • 19
    Reusser P,Riddell SR,Meyers JD,Greenberg PD. Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: Pattern of recovery and correlation with cytomegalovirus infection and disease. Blood 1991; 78: 13731380.
  • 20
    Li CR,Greenberg PD,Gilbert MJ,Goodrich JM,Riddell SR. Recovery of HLA-restricted cytomegalovirus (CMV)-specific T-cell responses after allogeneic bone marrow transplant: Correlation with CMV disease and effect of ganciclovir prophylaxis. Blood 1994; 83: 19711979.
  • 21
    Krause H,Hebart H,Jahn G,Muller CA,Einsele H. Screening for CMV-specific T cell proliferation to identify patients at risk of developing late onset CMV disease. Bone Marrow Transplant 1997; 19: 11111116.
  • 22
    Walter EA,Greenberg PD,Gilbert MJ,Finch RJ, Watanabe KS, Thomas ED, Riddell SR. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N Engl J Med 1995; 333: 10381044.
  • 23
    Einsele H,Roosnek E,Rufer N,Sinzger C, Riegler S, Loffler J, Grigoleit U, Moris A, Rammensee HG, Kanz L, Kleihauer A, Frank F, Jahn G, Hebart H. Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy. Blood 2002; 99: 39163922.
  • 24
    Lilleri D,Gerna G,Fornara C,Lozza L,Maccario R,Locatelli F. Prospective simultaneous quantification of human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in young recipients of allogeneic hematopoietic stem cell transplants. Blood 2006; 108: 14061412.
  • 25
    Kern F,Bunde T,Faulhaber N,Kiecker F, Khatamzas E, Rudawski IM, Pruss A, Gratama JW,Volkmer-Engert R, Ewert R, Reinke P, Volk HD, Picker LJ. Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals. J Infect Dis 2002; 185: 17091716.
  • 26
    Whitmire JK,Ahmed R. Costimulation in antiviral immunity: differential requirements for CD4+ and CD8+ T cell responses. Curr Opin Immunol 2000; 12: 448455.
  • 27
    Kern F,Surel IP,Faulhaber N,Frommel C,Schneider-Mergener J, Schonemann C, Reinke P, Volk HD. Target structures of the CD8+-T-cell response to human cytomegalovirus: The 72-kilodalton major immediate-early protein revisited. J Virol 1999; 73: 81798184.
  • 28
    Fallen PR,McGreavey L,Madrigal JA,Potter M, Ethell M, Prentice HG, Guimaraes A, Travers PJ. Factors affecting reconstitution of the T cell compartment in allogeneic haematopoietic cell transplant recipients. Bone Marrow Transplant 2003; 32: 10011014.
  • 29
    Khan N,Hislop A,Gudgeon N,Cobbold M, Khanna R, Nayak L, Rickinson AB, Moss PA. Herpesvirus-specific CD8 T cell immunity in old age: Cytomegalovirus impairs the response to a coresident EBV infection. J Immunol 2004; 173: 74817489.
  • 30
    Almanzar G,Schwaiger S,Jenewein B, Keller M,Herndler-Brandstetter D, Wurzner R, Shconitzer D,Grubeck-Loebenstein B. Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons. J Virol 2005; 79: 36753683.
  • 31
    Sester M,Sester U,Gartner B,Kubuschok B, Girndt M, Meyerhans A, Kohler H. Sustained high frequencies of specific CD4 T cells restricted to a single persistent virus. J Virol 2002; 76: 37483755.
  • 32
    Stone SF,Price P,Khan N,Moss PA,French MA. HIV patients on antiretroviral therapy have high frequencies of CD8 T cells specific for Immediate Early protein-1 of cytomegalovirus. AIDS 2005; 19: 555562.
  • 33
    Gallez-Hawkins G,Thao L,Lacey SF,Martinez J, Li X, Franck AAE, Lomeli NA, Longmate J, Diamond DJ, Spielberger R, Forman SJ, Zaia JA. Cytomegalovirus immune reconstitution occurs in recipients of allogeneic hematopoietic cell transplants irrespective of detectable cytomegalovirus infection. Biol Blood Marrow Transplant 2005; 11: 890902.
  • 34
    Ljungman P,Aschan J,Azinge JN, Brandt L, Ehrnst A, Hammarstrom V, Klaesson S, Linde A, Lonnqvist B, Ringden O, Wahren B, Gahrton G. Cytomegalovirus viraemia and specific T-helper cell responses as predictors of disease after allogeneic marrow transplantation. Br J Haematol 1993; 83: 118124.
  • 35
    Boeckh M,Leisenring W,Riddell SR,Bowden RA, Huang ML, Myerson D,Stevens-Ayers T, Flowers ME, Cunningham T, Corey L. Late cytomegalovirus disease and mortality in recipients of allogeneic hematopoietic stem cell transplants: Importance of viral load and T-cell immunity. Blood 2003; 101: 407414.
  • 36
    Gamadia LE,Remmerswaal EB,Weel JF,Bemelman F,van Lier RA,Ten Berge IJ. Primary immune responses to human CMV: a critical role for IFN-gamma-producing CD4+ T cells in protection against CMV disease. Blood 2003; 101: 26862692.
  • 37
    Sester M,Sester U,Gartner B,Heine G, Girndt M,Mueller-Lantzsch N, Meyerhans A, Kohler H. Levels of virus-specific CD4 T cells correlate with cytomegalovirus control and predict virus-induced disease after renal transplantation. Transplantation 2001; 71: 12871294.
  • 38
    Bronke C,Palmer NM,Jansen CA,Westerlaken GH, Polstra AM, Reiss P, Bakker M, Miedema F, Tesselaar K,van Baarle D. Dynamics of cytomegalovirus (CMV)-specific T cells in HIV-1-infected individuals progressing to AIDS with CMV end-organ disease. J Infect Dis 2005; 191: 873880.
  • 39
    Jacobson MA,Maecker HT,Orr PL,D'Amico R,Van Natta M,Li XD,Pollard RB,Bredt BM; Adult AIDS Clinical Trials Group and the Studies of Ocular Complications of AIDS Research Group. Results of a cytomegalovirus (CMV)-specific CD8+/interferon-gamma+ cytokine flow cytometry assay correlate with clinical evidence of protective immunity in patients with AIDS with CMV retinitis. J Infect Dis 2004; 189: 13621373.
  • 40
    Hebart H,Rauser G,Stevanovic S,Haenle C, Nussbaum AK, Meisner C, Bissinger AL, Tenzer S, Jahn G, Loeffler J, Rammensee HG, Schild H, Einsler H. A CTL epitope from human cytomegalovirus IE1 defined by combining prediction of HLA binding and proteasomal processing is the target of dominant immune responses in patients after allogeneic stem cell transplantation. Exp Hematol 2003; 31: 966973.
  • 41
    Cwynarski K,Ainsworth J,Cobbold M,Wagner S, Mahendra P, Apperley J, Goldman J, Craddock C, Moss PA. Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation. Blood 2001; 97: 12321240.
  • 42
    Ozdemir E,St John LS,Gillespie G,Rowland-Jones S,Champlin RE,Molldrem JJm,Komanduri KV. Cytomegalovirus reactivation following allogeneic stem cell transplantation is associated with the presence of dysfunctional antigen-specific CD8+ T cells. Blood 2002; 100: 36903697.
  • 43
    Waldrop SL,Davis KA,Maino VC,Picker LJ. Normal human CD4+ memory T cells display broad heterogeneity in their activation threshold for cytokine synthesis. J Immunol 1998; 161: 52845295.
  • 44
    Sandberg JK,Fast NM,Nixon DF. Functional heterogeneity of cytokines and cytolytic effector mlecules in human CD8+ T lymphocytes. J Immunol 2001; 167: 181187.
  • 45
    Sylwester AW,Mitchell BL,Edgar JB, Taormina C, Pelte C, Ruchti F, Sleath PR, Grabstein KH, Hosken NA, Kern F, Nelson JA, Picker LJ. Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects. J Exp Med 2005; 202: 673685.
  • 46
    Hakki M,Riddell SR,Storek J, Carter RA,Stevens-Ayers T, Sudour P, White K, Corey L, Boeckh M. Immune reconstitution to cytomegalovirus after allogeneic hematopoietic stem cell transplantation: Impact of host factors, drug therapy, and subclinical reactivation. Blood 2003; 102: 30603067.
  • 47
    Engstrand M,Lidehall AK,Totterman TH,Herrman B,Eriksson BM,Korsgren O. Cellular responses to cytomegalovirus in immunosuppressed patients: Circulating CD8+ T cells recognizing CMVpp65 are present but display functional impairment. Clin Exp Immunol 2003; 132: 96104.