Case Study Interpretation (CSI) sessions have become a well established, and popular, feature of Clinical Cytometry Society annual meetings. List mode files from clinical cases are provided for attendees to analyze and interpret, before discussion during the final session of the meeting. In response to requests to make these cases more widely available, the cases presented at the International Clinical Cytometry Society meeting held in Houston in 2010 are being published in the journal, along with list mode files and example analyses provided as Supporting Information.
The four CSI–Houston cases illustrate various aspects of flow cytometric immunophenotyping of T-cells, including disorders that may mimic T-cell neoplasms and phenotypic information useful for the classification of precursor and mature T-cell lymphoproliferative disorders. I hope you enjoy analyzing these cases in your own laboratory and comparing your strategy with that of the authors, use these cases to test your knowledge, and pick up information that will be useful in your practice of clinical flow cytometry.