Sexual dysfunction and physicians' perception in medicated patients with major depression in Taiwan
Article first published online: 5 JUN 2007
© 2007 Wiley-Liss, Inc.
Depression and Anxiety
Volume 25, Issue 9, pages E56–E62, September 2008
How to Cite
Chen, K. C., Yang, Y. K., Lee, I. H., Yeh, T. L., Lu, R.-B. and Chen, P. S. (2008), Sexual dysfunction and physicians' perception in medicated patients with major depression in Taiwan. Depress. Anxiety, 25: E56–E62. doi: 10.1002/da.20312
- Issue published online: 9 SEP 2008
- Article first published online: 5 JUN 2007
- Manuscript Accepted: 30 JAN 2007
- Manuscript Revised: 10 JAN 2007
- Manuscript Received: 16 AUG 2006
- Glaxo Smith Kline Taiwan, Ltd.
- NCKU hospital
- sexual dysfunction;
- major depression;
- physician's perception
Although prevalent during antidepressant treatment, sexual dysfunction (SD) is frequently ignored by both physicians and patients in Asia. In spite of impact of SD on medicated patients with major depression, sexual issues and illness remain a forbidden topic for most Asian people. The aims of this study were to: (1) estimate the prevalence of SD among stable outpatients taking different antidepressants in Taiwan; (2) investigate the factors related to SD; (3) compare physician-perceived with patient-reported prevalence rates of antidepressant-associated SD; and (4) study the differences of SD among antidepressant subgroups. In this cross-sectional observational study, 125 medicated patients with major depression were recruited. Patients were assessed using the Changes in Sexual Functioning Questionnaire (CSFQ), Taiwanese Depression Questionnaire (TDQ), Quality of Life Index (QOL), and neuroticism scores in the Maudsley Personality Inventory (MPI). Sixty-two physicians completed the Physician Antidepressant Experience Questionnaire. The estimated prevalence rate of SD was 53.6% (95% CI = 44.9–62.3%) in medicated patients with major depression. There were no significant differences in prevalence rate of SD among different antidepressants. The SD subgroup had poorer quality of life and lower moods than the non-dysfunction subgroup. An underestimation of the prevalence of SD by physicians was noted. Because antidepressant-associated SD is highly prevalent and seriously underestimated by physicians, greater physicians' recognition and better patients' education are imperative when prescribing antidepressants. Depression and Anxiety. © 2007 Wiley-Liss, Inc.