This article is a US Government work and, as such, is in the public domain in the United States of America.
Nicotine dependence mediates the relations between insomnia and both panic and posttraumatic stress disorder in the NCS-R sample†
Article first published online: 12 OCT 2007
This article is a US Government work and, as such, is in the public domain in the United States of America. Published 2007 Wiley-Liss, Inc.
Depression and Anxiety
Volume 25, Issue 8, pages 670–679, August 2008
How to Cite
Babson, K. A., Feldner, M. T., Sachs-Ericsson, N., Schmidt, N. B. and Zvolensky, M. J. (2008), Nicotine dependence mediates the relations between insomnia and both panic and posttraumatic stress disorder in the NCS-R sample. Depress. Anxiety, 25: 670–679. doi: 10.1002/da.20374
- Issue published online: 25 AUG 2008
- Article first published online: 12 OCT 2007
- Manuscript Accepted: 11 JUL 2007
- Manuscript Revised: 3 JUN 2007
- Manuscript Received: 6 APR 2007
- Arkansas Biosciences Institute
- National Institute on Drug Abuse research. Grant Numbers: 1 R01 DA018734-01A1, R03 DA16307-01, 1 R21 DA016227-01
- nicotine dependence;
Although a growing literature has demonstrated elevations in insomnia symptoms among persons with either panic disorder (PD) or posttraumatic stress disorder (PTSD) relative to people without psychopathology, comparably little is known about processes underlying these associations. In recognition of this important gap in the literature, this study tested nicotine dependence as a partial mediator of the relations between insomnia symptoms and both PD and PTSD among a nationally representative sample of 5,692 (3,311 females; Mage=43.33, SD=16.55) adults from the National Comorbidity Survey-Replication. Consistent with hypotheses, nicotine dependence partially mediated the relations between insomnia and both PD and PTSD after controlling for variance accounted for by diagnoses of major depressive episodes, drug and alcohol dependence, and gender. Overall, results suggest nicotine dependence may be a possible mechanism that underlies insomnia among those with PD and PTSD. Depression and Anxiety 0:1–10, 2007. Published 2007 Wiley-Liss, Inc.