Grant sponsor: National Institute of Mental Health; grant number F31MH085416 (to Tierney Lorenz); grant sponsor: NICHD; grant number RO1 HD051676 (to Cindy Meston) and grant number T32HD049336 (supporting Tierney Lorenz).
EXERCISE IMPROVES SEXUAL FUNCTION IN WOMEN TAKING ANTIDEPRESSANTS: RESULTS FROM A RANDOMIZED CROSSOVER TRIAL
Article first published online: 1 NOV 2013
© 2013 Wiley Periodicals, Inc.
Depression and Anxiety
Anxiety and Depression Co-Morbidity and the 2014 Klein Award Winner
Volume 31, Issue 3, pages 188–195, March 2014
How to Cite
Lorenz, T. A. and Meston, C. M. (2014), EXERCISE IMPROVES SEXUAL FUNCTION IN WOMEN TAKING ANTIDEPRESSANTS: RESULTS FROM A RANDOMIZED CROSSOVER TRIAL. Depress. Anxiety, 31: 188–195. doi: 10.1002/da.22208
- Issue published online: 7 MAR 2014
- Article first published online: 1 NOV 2013
- Manuscript Accepted: 5 OCT 2013
- Manuscript Revised: 1 OCT 2013
- Manuscript Received: 19 AUG 2013
- National Institute of Mental Health. Grant Number: F31MH085416
- NICHD. Grant Number: RO1 HD051676
- National Institute of Child Health and Human Development (NICHD). Grant Number: T32HD049336
- sexual function;
- sexual satisfaction;
In laboratory studies, exercise immediately before sexual stimuli improved sexual arousal of women taking antidepressants . We evaluated if exercise improves sexual desire, orgasm, and global sexual functioning in women experiencing antidepressant-induced sexual side effects.
Fifty-two women who were reporting antidepressant sexual side effects were followed for 3 weeks of sexual activity only. They were randomized to complete either three weeks of exercise immediately before sexual activity (3×/week) or 3 weeks of exercise separate from sexual activity (3×/week). At the end of the first exercise arm, participants crossed to the other. We measured sexual functioning, sexual satisfaction, depression, and physical health.
Exercise immediately prior to sexual activity significantly improved sexual desire and, for women with sexual dysfunction at baseline, global sexual function. Scheduling regular sexual activity significantly improved orgasm function; exercise did not increase this benefit. Neither regular sexual activity nor exercise significantly changed sexual satisfaction.
Scheduling regular sexual activity and exercise may be an effective tool for the behavioral management of sexual side effects of antidepressants.