Medullary thyroid carcinoma presenting as rectangular cell type on fine-needle aspiration

Authors

  • Andrew M. Schreiner M.D.,

    Corresponding author
    1. Department of Pathology and Laboratory Medicine, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York
    • Papanicolaou Cytology Laboratory, New York Presbyterian Hospital-Weill Cornell Medical Center, 525 East 68 Street, Suite F-766, New York, NY 10065
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  • Grace C. H. Yang M.D., F.I.A.C.

    1. Department of Pathology and Laboratory Medicine, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York
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Abstract

Medullary thyroid carcinoma typically presents as dyscohesive plasmacytoid, spindled, or polygonal cells on fine-needle aspiration smears. We recently encountered a case of sporadic medullary thyroid carcinoma that presented as a hypercellular aspirate composed of cohesive aggregates of rectangle-shaped cells. The case was mistakenly reported as a hypercellular follicular neoplasm on cytology. Subsequent thyroidectomy revealed medullary carcinoma. We draw attention to this distinctive rectangular cell type as an additional morphology for medullary thyroid carcinoma. Diagn. Cytopathol. 2009. © 2009 Wiley-Liss, Inc.

Ancillary