Images in Cytology
Cytodiagnosis of histoplasmosis: Case reports from two patients with variable clinical presentation
Article first published online: 19 SEP 2011
Copyright © 2011 Wiley Periodicals, Inc.
Volume 40, Issue 12, pages 1090–1092, December 2012
How to Cite
Singh, S., Chhabra, S., Goyal, R., Garg, S. (2012), Cytodiagnosis of histoplasmosis: Case reports from two patients with variable clinical presentation. Diagn. Cytopathol., 40: 1090–1092. doi: 10.1002/dc.21803
- Issue published online: 17 NOV 2012
- Article first published online: 19 SEP 2011
- Manuscript Accepted: 13 JUN 2011
- Manuscript Received: 24 MAR 2011
- Histoplasma capsulatum;
- dimorphic fungus;
- fine-needle aspiration cytology
Histoplasmosis has emerged as an important opportunistic fungal infection in immunocompromised patients. Histoplasma is a dimorphic fungus that primarily involves lung and the environmental reservoir is soil. Although several cases of histoplasmosis have been reported in India but cytological diagnosis was made in a few cases. We are presenting two cases of histoplasmosis diagnosed on fine-needle aspiration cytology. In the first case, pulmonary histoplasmosis was diagnosed on transbronchial needle aspiration of lung in a 41-year-old immunocompetent male, while second case was of disseminated histoplasmosis in 40-year-old immunocompromised female diagnosed on cytology of cervical lymph node. FNAC is a simple, safe, and rapid technique to establish the initial diagnosis, thus promoting early treatment and favorable outcome especially in the immunocompromised patients. Diagn. Cytopathol. 2011; © 2011 Wiley Periodicals, Inc.