Current Trends Review
Teratological effects of industrial solvents
Article first published online: 5 OCT 2004
Copyright © 1988 Alan R. Liss, Inc.
Drug Development Research
Volume 13, Issue 4, pages 205–212, 1988
How to Cite
Pradhan, S., Ghosh, T. K. and Pradhan, S. N. (1988), Teratological effects of industrial solvents. Drug Dev. Res., 13: 205–212. doi: 10.1002/ddr.430130403
- Issue published online: 6 MAR 2008
- Article first published online: 5 OCT 2004
- Manuscript Accepted: 6 APR 1988
- Manuscript Received: 28 MAR 1988
- fetal alcohol syndrome;
- glycol ethers
Increasing exposure of pregnant mothers to various industrial solvents due to voluntary abuse or involuntary exposure in the work place is raising the possibility of production of teratological effects in the offsprings. Ethanol, which can be broadly categorized as a solvent and which is also extensively abused, is well known for its teratological deragements in humans, termed as “fetal alcohol syndrome” as well as in animals. Benzene and its derivatives (xylene and toluene), alcohols, glycols and glycol ethers, and other solvents have also been reported to produce various types of teratogenic effects in animal (e.g., mice, rats, and rabbits) studies. In the case of toluene, some teratogenic anomalies have been reported in three children of mothers exposed to pure toluene vapor throughout the pregnancy.