Potentiation of atropine-induced retardation of small intestine transit in mice by a pulsed magnetic field

Authors

  • R. Santini,

    Corresponding author
    1. Laboratoire de Physiologie-Pharmacodynamie, Institut National des Sciences Appliquées, Villeurbanne, France
    • Laboratoire de Physiologie-Pharmacodynamie, Institut National des Sciences Appliquées. 20 av. Albert Einstein. 69621 Villeurbanne Cedex, France
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  • M. Seigne

    1. Laboratoire de Physiologie-Pharmacodynamie, Institut National des Sciences Appliquées, Villeurbanne, France
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Abstract

The interaction of a pulsed (100 and 50 Hz) magnetic field (90 μT) with the effect of atropine on small intestine transit was studied in mice. Both frequencies of the magnetic field significantly potentiated the atropine-induced delay in intestinal transit but did not affect intestinal transit per se. This result further strengthens previous observations on interactions between electromagnetic fields and the actions of drugs. © 1992 Wiley-Liss, Inc.

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