Neuroimaging in pediatric traumatic brain injury: Current and future predictors of functional outcome
Article first published online: 1 JUN 2009
Copyright © 2009 Wiley-Liss, Inc.
Developmental Disabilities Research Reviews
Special Issue: Acquired Central Nervous System Injuries
Volume 15, Issue 2, pages 117–123, 2009
How to Cite
Suskauer, S. J. and Huisman, T. A.G.M. (2009), Neuroimaging in pediatric traumatic brain injury: Current and future predictors of functional outcome. Dev Disabil Res Revs, 15: 117–123. doi: 10.1002/ddrr.62
- Issue published online: 1 JUN 2009
- Article first published online: 1 JUN 2009
- Manuscript Accepted: 2 APR 2009
- Manuscript Received: 13 FEB 2009
- National Institute of Child Health and Human Development. Grant Number: K12HD001097
- traumatic brain injury;
Although neuroimaging has long played a role in the acute management of pediatric traumatic brain injury (TBI), until recently, its use as a tool for understanding and predicting long-term brain-behavior relationships after TBI has been limited by the relatively poor sensitivity of routine clinical imaging for detecting diffuse axonal injury (DAI). Newer magnetic resonance-based imaging techniques demonstrate improved sensitivity to DAI. Early research suggests that these techniques hold promise for identifying imaging predictors and correlates of chronic function, both globally and within specific neuropsychological domains. In this review, we describe the principles of new, advanced imaging techniques including diffusion weighted and diffusion tensor imaging, susceptibility weighted imaging, and 1H-magnetic resonance spectroscopy. In addition, we summarize current research demonstrating their early success in establishing relationships between imaging measures and functional outcomes after TBI. With the ongoing research, these imaging techniques may allow earlier identification of possible chronic sequelae of tissue injury for each child with TBI, thereby facilitating efficacy and efficiency in delivering successful rehabilitation services. © 2009 Wiley-Liss, Inc. Dev Disabil Res Rev 2009;15:117–123.