Independent and combined associations of abdominal obesity and seated resting heart rate with type 2 diabetes among older Chinese: the Guangzhou Biobank Cohort Study

Authors

  • Bríain ó Hartaigh,

    1. Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, Edgbaston, Birmingham, UK
    2. School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    Search for more papers by this author
  • Chao Qiang Jiang,

    1. Guangzhou Occupational Disease Prevention and Treatment Centre, Guangzhou No. 12 Hospital, Guangzhou, People's Republic of China
    Search for more papers by this author
  • Jos A. Bosch,

    1. School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    Search for more papers by this author
  • Wei Sen Zhang,

    1. Guangzhou Occupational Disease Prevention and Treatment Centre, Guangzhou No. 12 Hospital, Guangzhou, People's Republic of China
    Search for more papers by this author
  • Kar Keung Cheng,

    1. Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, Edgbaston, Birmingham, UK
    Search for more papers by this author
  • Tai Hing Lam,

    1. Department of Community Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, People's Republic of China
    Search for more papers by this author
  • G. Neil Thomas

    Corresponding author
    1. Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, Edgbaston, Birmingham, UK
    • Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Search for more papers by this author

Abstract

Background

Central obesity and poor physical fitness predict the development of type 2 diabetes and cardiovascular mortality among Caucasian populations. We studied the independent and combined effect of abdominal obesity and seated resting heart rate used as an indicator of physical fitness, on the presence of type 2 diabetes among 30 519 older residents of Guangzhou, Southern China.

Methods

Participants were stratified into four groups, based on the Asian criteria for abdominal obesity (≥90/≥ 80 cm in men/women) and the 75% cut-off point for seated resting heart rate (≥83 beats per min). The association with type 2 diabetes was assessed using multivariable logistic regression.

Results

A total of 3777 (12.7%) volunteers were diagnosed with type 2 diabetes, which was independently associated with seated resting heart rate and, in particular, increasing levels of abdominal obesity (p < 0.001). An odds ratio of 3.93 (95% confidence interval = 3.48–4.43) was identified for type 2 diabetes in participants who were obese with a seated resting heart rate ≥ 83 beats per min after adjusting for potential confounders.

Conclusions

Higher seated resting heart rate, a marker of poor physical fitness, independently doubles the risk of type 2 diabetes. The strength of this association is further increased when abdominal obesity is considered. Copyright © 2011 John Wiley & Sons, Ltd.

Ancillary