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Current Awareness

  • 1. Reviews & symposia
  • Special issue: Diabetes and Lipids - A Call to Action: Proceedings of a Satellite symposium, XXXVth Meeting of the European Association for the Diabetes, 29th September 1999, Brussels, Belgium. Acta Diabetol (2001) 38:
  • Special issue on insulin secretion. Diabetes (2002) 51: 51
  • Special issue: The Second International Symposium on Free Radical and Vascular Biology of Diabetes. Diabetes Res Clin Pract (2001) 54:
  • Treatment of hypertension in adults with diabetes (Position Statement). Diabetes Care (2002) 25: 199
  • Ahmed AM, Ahmed NH. Diabetes mellitus in Sudan: The size of the problem and the possibilities of efficient care (Review). Pract Diab Int (2001) 18: 324
  • Arauz-Pacheco C, Parrott MA, Raskin P. The treatment of hypertension in adult patients with diabetes (Review). Diabetes Care (2002) 25: 134
  • Beattie AH. The dietetic treatment of obesity (Review). Pract Diab Int (2001) 18: 321
  • Bonora E, Muggeo M. Postprandial blood glucose as a risk factor for cardiovascular disease in type 2 diabetes: The epidemiological evidence (Review). Diabetologia (2001) 44: 2107
  • Eizirik DL, Mandrup-Poulsen T. A choice of death: The signal-transduction of immune-mediated β-cell apoptosis (Review). Diabetologia (2001) 44: 2115
  • Franz MJ, Bantle JP, Beebe CA, Brunzell JD, Chiasson JL, Garg L, Holzmeister LA, Hoogwerf B, Mayer-Davis E, Mooradian AD, Purnell JQ, Wheeler M. Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications (Review). Diabetes Care (2002) 25: 148
  • Kuzuya T, Nakagawa S, Satoh J, Kanazawa Y, Iwamoto Y, Kobayashi M, Nanjo K, Sasaki A, Seino Y, Ito C, Shima K, Nonaka K, Kadowaki T. Report of the Committee on the classification and diagnostic criteria of diabetes mellitus. Diabetes Res Clin Pract (2002) 55: 65
  • Mohn A, Dunger DB, Chiarelli F. The potential role of insulin analogues in the treatment of children and adolescents with type 1 diabetes mellitus (Review). Diabetes Nutr Metab (2001) 14: 349
  • Triad Study. The Translating Research Into Action for Diabetes (TRIAD) Study: A multicenter study of diabetes in managed care. Diabetes Care (2002) 25: 386
  • Wales JK. Drug treatment in obesity (Review). Pract Diab Int (2002) 19: 25
  • Webber J. The comorbidities of obesity (Review). Pract Diab Int (2001) 18: 292
  • Wilding JPH. Causes of obesity (Review). Pract Diab Int (2001) 18: 288
  • 2. General
  • Biaggioni I, Davis SN. Caffeine: A cause of insulin resistance? (Editorial). Diabetes Care (2002) 25: 399
  • Cradock S, Shaw K. The Diabetes National Service Framework: Setting the standard. Pract Diab Int (2002) 19: 3
  • Cummings M. Screening for diabetic retinopathy. Pract Diab Int (2002) 19: 5
  • Dean HJ. Dancing with many different ghosts: Treatment of youth with type 2 diabetes (Editorial). Diabetes Care (2002) 25: 237
  • Greenwood K, Shaw K. The National Research Strategy: Implications for diabetes research in the NHS. Pract Diab Int (2001) 18: 303
  • Halban P. European diabetes research: Hopes and threats. Pract Diab Int (2001) 18: 305
  • Riddle MC. Timely addition of insulin to oral therapy for type 2 diabetes (Editorial). Diabetes Care (2002) 25: 395
  • Rossner S. Obesity and type 2 diabetes. Pract Diab Int (2001) 18: 263
  • Tayer JA. Is weight loss a cure for type 2 diabetes? (Editorial). Diabetes Care (2002) 25: 397
  • Wales JK. ‘If you think diabetes care has problems...’. Pract Diab Int (2001) 18: 263
  • 3. Genetics
  • Arya R, Blangero J, Williams K, Almasy L, Dyer TD, Leach RJ, O'Connell P, Stern MP, Duggirala R. Factors of insulin resistance syndrome-related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic Mexican-Americans. Diabetes (2002) 51: 841
  • Banchuin N, Boonyasrisawat W, Pulsawat P, Vannasaeng S, Deerochanawong C, Sriussadaporn S, Ploybutr S, Pasurakul T, Yenchitsomanus PT. No abnormalities of reg1α and reg1β gene associated with diabetes mellitus. Diabetes Res Clin Pract (2002) 55:105
  • Echwald SM, Bach H, Vestergaard H, Richelsen B, Kristensen K, Drivsholm T, Borch-Johnsen K, Hansen T, Pedersen O. A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro. Diabetes (2002) 51: 1
  • Ek J, Andersen G, Urhammer SA, Gaede PH, Drivsholm T, Borch-Johnsen K, Hansen T, Pedersen O. Mutation analysis of peroxisome proliferator-activated receptor-γ coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to type 2 diabetes mellitus. Diabetologia (2001) 44: 2220
  • Elbein SC, Hasstedt SJ. Quantitative trait linkage analysis of lipid-related traits in familial type 2 diabetes: Evidence for linkage of triglyceride levels to chromosome 19q. Diabetes (2002) 51: 528
  • Garant MJ, Kao WHL, Brancati F, Coresh J, Rami TM, Hanis CL, Boerwinkle E, Shuldiner AR. SNP43 of CAPN10 and the risk of type 2 diabetes in African-Americans: The atherosclerosis risk in communities study. Diabetes (2002) 51: 231
  • Gillespie KM, Gale EAM, Bingley PJ. High familial risk and genetic susceptibility in early onset childhood diabetes. Diabetes (2002) 51: 210
  • Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Kimura S, Tomita M, Kimura S, Ito C, Froguel P, Kadowaki T. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes (2002) 51: 536
  • Hashim Y, Shepherd D, Wiltshire S, Holman RR, Levy JC, Clark A, Cull CA. Butyrylcholinesterase K variant on chromosome 31 is associated with type 2 diabetes white Caucasian subjects. Diabetologia (2001) 44: 2227
  • Huopio H, Vauhkonen I, Komulainen J, Niskanen L, Otonkoski T, Laakso M. Carriers of an inactivating β-cell ATP-sensitive K+ channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion. Diabetes Care (2002) 25:101
  • Kawasaki I, Tahara H, Emoto M, Shoji T, Nishizawa Y. Relationship between TaqIB cholesteryl ester transfer protein gene polymorphism and macrovascular complications in Japanese patients with type 2 diabetes. Diabetes (2002) 51: 871
  • Kupila A, Keskinen P, Simell T, Erkkila S, Arvilommi P, Korhonen S, Kimpimaki T, Sjoroos M, Ronkainen M, Ilonen J, Knip M, Simell O. Genetic risk determines the emergence of diabetes-associated autoantibodies in young children. Diabetes (2002) 51: 646
  • Laybutt DR, Kaneto H, Hasenkamp W, Grey S, Jonas JC, Sgroi DC, Groff A, Ferran C, Bonner-Weir S, Sharma A, Weir GC. Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to β-cell survival during chronic hyperglycemia. Diabetes (2002)51: 413
  • Lee HJ, Ahn CW, Kim SJ, Song YD, Lim SK, Kim KR, Lee HC, Huh KB. Mutation in hepatocyte nuclear factor-1α is not a common cause of MODY and early-onset type 2 diabetes in Korea. Acta Diabetol (2001) 38: 123
  • Lynn S, Evans JC, White C, Frayling TM, Hattersley AT, Turnbull DM, Horikawa Y, Cox NJ, Bell GI, Walker M. Variation in the calpain-10 gene affects blood glucose levels in the British population. Diabetes (2002) 51: 247
  • Meigs JB, Panhuysen CIM, Myers RH, Wilson PWF, Cupples LA. A genome-wide scan for loci linked to plasma levels of glucose and HbA1c in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study. Diabetes (2002) 51: 833
  • Mentuccia D, Proietti-Pannunzi L, Tanner K, Bacci V, Pollin TI, Poehlman ET, Shuldiner AR, Celi FS. Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: Evidence of interaction with the Trp64Arg variant of the β-3-adrenergic receptor. Diabetes (2002) 51: 880
  • Mochizuki M, Amemiya S, Kobayashi K, Kobayashi K, Ishihara T, Aya M, Kato K, Kasuga A, Nakazawa S. The association of Ala45Thr polymorphism in NeuroD with child-onset type 1a diabetes in Japanese. Diabetes Res Clin Pract (2002) 55: 11
  • Nakajima K, Tanaka Y, Nomiyama T, Ogihara T, Piao L, Sakai K, Onuma T, Kawamori R. Chemokine receptor genotype is associated with diabetic nephropathy in Japanese with type 2 diabetes. Diabetes (2002) 51: 238
  • Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H. Systematic search for single nucleotide polymorphisms in the resistin gene: The absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes. Diabetes(2002) 51: 863
  • Park HK, Ahn CW, Lee GT, Kim SJ, Song YD, Lim SK, Kim KR, Huh KB, Lee HC. (AC)n polymorphism of aldose reductase gene and diabetic microvascular complications in type 2 diabetes mellitus. Diabetes Res Clin Pract (2002) 55: 151
  • Rice T, Chagnon YC, Perusse L, Borecki IB, Ukkola O, Rankinen T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Bouchard C, Rao DC. A genomewide linkage scan for abdominal subcutaneous and visceral fat in black and white families: The HERITAGE Family Study. Diabetes (2002)51: 848
  • Rigoli L, Caruso RA, Zuccarello D, Rigoli M, Barberi I. Mitochondrial 3243 BP mutation: A case report. Diabetes Nutr Metab (2001) 14: 343
  • Schneider J, Kreuzer J, Hamann A, Nawroth PP, Dugi KA. The proline 12 alanine substitution in the peroxisome proliferator-activated receptor-γ2 gene is associated with lower lipoprotein lipase activity in vivo. Diabetes (2002) 51: 867
  • Schwanstecher C, Meyer U, Schwanstecher M. KIR6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic β-cell ATP-sensitive K+ channels. Diabetes (2002) 51: 875
  • Sentinelli F, Romeo S, Arca M, Filippi E, Leonetti F, Banchieri M, Di Mario U, Baroni MG. Human resistin gene, obesity, and type 2 diabetes: Mutation analysis and population study. Diabetes (2002) 51: 860
  • Solini A, Dalla'Vestra M, Saller A, Nosandini R, Crepaldi G, Fioretto P. The angiotensin-converting enzyme DD genotype is associated with glomerulopathy lesions in type 2 diabetes. Diabetes (2002) 51: 251
  • Stumvoll M, Tschritter O, Fritsche A, Staiger H, Renn W, Weisser M, Machicao F, Haring H. Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: Interaction with family history of type 2 diabetes. Diabetes (2002) 51: 37
  • T'Hart LM, Nijpels G, Dekker JM, Maassen JA, Heine RJ, Van Haeften TW. Variations in insulin secretion in carriers of gene variants in IRS-1 and -2. Diabetes (2002) 51: 884
  • Taylor KW, Cassell PG, Hitman GA. Familial diabetes with insulin dependency in later life involving all six members of one generation of a family. Pract Diab Int (2001) 18: 283
  • Ukkola O, Sun G, Bouchard C. Insulin-like growth factor 2 (IGF2) and IGF-binding protein 1 (IGFBP1) gene variants are associated with overfeeding-induced metabolic changes. Diabetologia (2001) 44: 2231
  • Vaessen N, Heutink P, Houwing-Duistermaat JJ, Snijders PJLM, Rademaker T, Testers L, Batstra MR, Sandkuijl LA, Van Duijn CM, Oostra BA. A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands. Diabetes (2002) 51: 856
  • Weng JP, Ekelund M, Lehto M, Li HY, Ekberg G, Frid A, Aberg A, Groop LC, Berntorp K. Screening for MODY mutations, GAD antibodies, and type 1 diabetes-associated HLA genotypes in women with gestational diabetes mellitus. Diabetes Care (2002) 25: 68
  • Yasuda T, Kajimoto Y, Fijutani Y, Watada H, Yamamoto S, Watarai T, Umayahara Y, Matsuhisa M, Gorogawa S, Kuwayana Y, Tano Y, Yamasaki Y, Hori M. PAX6 mutation as a genetic factor common to aniridia and glucose intolerance. Diabetes (2002) 51: 224
  • Zhu XF, Cooper RS, Luke A, Chen GJ, Wu XD, Kan DH, Chakravarti A, Weder A. A genome-wide scan for obesity in African-Americans. Diabetes (2002) 51: 541
  • 4. Epidemiology
  • Asakawa H, Tokunaga K, Kawakami F. Relationship of abdominal fat with metabolic disorders in diabetes mellitus patients. Diabetes Res Clin Pract (2002) 55: 139
  • De Berardis G, Franciosi M, Belfiglio M, Di Nardo B, Greenfield S, Kaplan SH, Pellegrini F, Sacco M, Tognoni G, Valentini M, Nicolucci A. Erectile dysfunction and quality of life in type 2 diabetic patients: A serious problem too often overlooked. Diabetes Care (2002)25: 284
  • Gambaro G, Bax G, Fusaro M, Normanno M, Manani SM, Zanella M, D'Angelo A, Fedele D, Favaro S. Cigarette smoking is a risk factor for nephropathy and its progression in type 2 diabetes mellitus. Diabetes Nutr Metab (2001) 14: 337
  • Gregg EW, Mangione CM, Cauley JA, Thompson TJ, Schwartz AV, Ensrud KE, Nevitt MC. Diabetes and incidence of functional disability in older women. Diabetes Care (2002) 25: 61
  • Johny KV, Nampoory MRN, Costandi JN, Gupta RK, Ninan VT, Samhan M, Muzairai I, Al Mousawi M. High incidence of post-transplant diabetes mellitus in Kuwait. Diabetes Res Clin Pract (2002) 55: 123
  • King H, Djumaeva S, Abdullaev B, Dobo MG. Epidemiology of glucose intolerance and associated factors in Uzbekistan: A survey in Sirdaria province. Diabetes Res Clin Pract (2002) 55: 19
  • Knowles NG, Landchild MA, Fujimoto WY, Kahn SE. Insulin and amylin release are both diminished in first-degree relatives of subjects with type 2 diabetes. Diabetes Care (2002) 25: 292
  • Kudva YC, Reynolds C, O'Brien T, Powell C, Oberg AL, Crotty TB. “Diabetic mastopathy,” or sclerosing lymphocytic lobulitis, is strongly associated with type 1 diabetes. Diabetes Care (2002) 25: 121
  • Lee ET, Welty TK, Cowan LD, Yang WY, Rhoades DA, Devereux R, Go O, Fabsitz R, Howard BV. Incidence of diabetes in American Indians of three geographic areas: The Strong Heart Study. Diabetes Care (2002) 25: 49
  • Marra G, Cotroneo P, Pitocco D, Manto A, Di Leo MAS, Ruotolo V, Caputo S, Giardina B, Ghirlanda G, Santini SA. Early increase of oxidative stress and reduced antioxidant defenses in patients with uncomplicated type 1 diabetes: A case for gender difference. Diabetes Care (2002) 25: 370
  • McGarry JD. Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes (Banting Lecture 2001). Diabetes (2002) 51: 7
  • Nielsen S, Emborg C, Molbak AG. Mortality in concurrent type 1 diabetes and anorexia nervosa. Diabetes Care (2002) 25: 309
  • Punnose J, Agarwal MM, El Khadir A, Devadas K, Mugamer IT. Childhood and adolescent diabetes mellitus in Arabs residing in the United Arab Emirates. Diabetes Res Clin Pract (2002) 55: 29
  • Roper NA, Bilous RW, Kelly WF, Unwin NC, Connolly VM. Cause-specific mortality in a population with diabetes: South Tees Diabetes mortality study. Diabetes Care (2002) 25: 43
  • Weijers RNM, Bekedam DJ, Smulders YM. Determinants of mild gestational hyperglycemia and gestational diabetes mellitus in a large Dutch multiethnic cohort. Diabetes Care (2002) 25: 72
  • 5. Immunology
  • Kawabata Y, Ikegami H, Kawaguchi Y, Fujisawa T, Shintani M, Ono M, Nishino M, Uchigata Y, Lee I, Ogihara T. Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and DQ haplotypes to susceptibility to type 1 diabetes. Diabetes (2002) 51: 545
  • Kohno T, Kobashiri Y, Sugie Y, Takai S, Watabe K, Kaino Y, Kida K. Antibodies to food antigens in Japanese patients with type 1 diabetes mellitus. Diabetes Res Clin Pract (2002) 55: 1
  • Lee WJ, Lee HW, Palmer JP, Park KS, Lee HK, Park JY, Hong SK, Lee KU. Islet cell autoimmunity and mitochondrial DNA mutation in Korean subjects with typical and atypical type 1 diabetes. Diabetologia (2001) 44: 2187
  • Piganelli JD, Flores SC, Cruz C, Koepp J, Batinic-Haberle I, Crapo J, Day B, Kachadourian R, Young R, Bradley B, Haskins K. A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone. Diabetes (2002)51: 347
  • Thiessen S, Serra P, Amrani A, Verdaguer J, Santamaria P. T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes. Diabetes (2002) 51: 325
  • Thomas HE, Darwich R, Corbett JA, Kay TWH. Interleukin-1 plus γ-interferon-induced pancreatic β-cell dysfunction is mediated by β-cell nitric oxide production. Diabetes (2002) 51: 311
  • Vozarova B, Weyer C, Lindsay RS, Pratley RE, Bogardus C, Tataranni PA. High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes. Diabetes (2002) 51: 455
  • 6. Obesity
  • Franckhauser S, Munoz S, Pujol A, Casellas A, Riu E, Otaegui P, Su BL, Bosch F. Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance. Diabetes (2002) 51: 624
  • Garcia-Lorda P, Bullo M, Vila R, Grasa MD, Alemany M, Salas-Salvado J. Leptin concentrations do not correlate with fat mass nor with metabolic risk factors in morbidity obese females. Diabetes Nutr Metab (2001) 14: 329
  • Greco AV, Mingrone G, Giancaterini A, Manco M, Morroni M, Cinti S, Granzotto M, Vettor R, Camastra S, Ferrannini E. Insulin resistance in morbid obesity: Reversal with intramyocellular fat depletion. Diabetes (2002) 51: 144
  • Kobayashi H, Ogawa Y, Shitani M, Ebihara K, Shimodahira M, Iwakura T, Hino M, Ishihara T, Ikekubo K, Kurahachi H, Nakao K. A novel homozygous missense of melanocortin-4 receptor (MC4R) in a Japanese woman with severe obesity. Diabetes (2002) 51: 243
  • Trovato GM, Catalano D, Caruso G, Squatrito R, Venturino M, Degano C, Di Fazzio S. Relationship between cardiac function and insulin resistance in obese patients. Diabetes Nutr Metab (2001) 14: 325
  • 7. Prediction and prevention
  • Oh JY, Barrett-Connor E, Wedick NM, Wingard DL. Endogenous sex hormones and the development of type 2 diabetes in older men and women: The Rancho Bernardo Study. Diabetes Care (2002) 25: 55
  • Srinivasan SR, Myers L, Berenson GS. Predictability of childhood adiposity and insulin for developing insulin resistance syndrome (syndrome X) in young adulthood: The Bogalusa Heart Study. Diabetes (2002) 51: 204
  • 8. Intervention:
  • b) Care
  • Standards of medical care for patients with diabetes mellitus (Position Statement). Diabetes Care (2002) 25: 213
  • The DAWN (Diabetes Attitudes, Wishes and Needs) Study. Pract Diab Int (2002) 19: 22
  • Avery L. Time to reflect: What makes a difference in diabetes care?. Pract Diab Int (2001) 18: 317
  • Cook S, Herold K, Edidin DV. Increasing problem solving in adolescents with type 1 diabetes: The choices diabetes program. Diabetes Educator (2002) 28: 115
  • Cranston IC, Whitefield L, Illet G, Ibrahim S. Bexley diabetes retinal screening programme. Pract Diab Int (2002) 19: 16
  • Davis TME, Bridgford A. A comprehensive patient-held record for diabetes. Part two: Large-scale assessment of the Diabetes Databank by patients and health care workers. Pract Diab Int (2001) 18: 311
  • Egede LE, Ye XB, Zheng DV, Silverstein MD. The prevalence and pattern of complementary and alternative medicine use in individuals with diabetes. Diabetes Care (2002) 25: 324
  • Esbester M. The Portsmouth retinopathy screening scheme. Pract Diab Int (2002) 19: 14
  • Gallagher A, Hutchison RS, Kelly WF. The challenge of pregnancy in the DIDMOAD syndrome. Pract Diab Int (2001) 18: 281
  • Gilliland SS, Azen SP, Perez GE, Carter JS. Strong in body and spirit: Lifestyle intervention for Native American adults with diabetes in New Mexico. Diabetes Care (2002) 25: 78
  • Harwell TS, Dettori N, McDowall JM, Quesenberry K, Priest L, Butcher MK, Flook BN, Helgerson SD, Gohdes D. Do persons with diabetes know their (A1C) number? Diabetes Educator (2002) 28: 99
  • Hearnshaw H, Hopkins J, Wild A, MacKinnon M, Gadsby R, Dale J. Mandatory, multidisciplinary education in diabetes care. Can it meet the needs of primary care organisations? Pract Diab Int (2001) 18: 274
  • Levetan CS, Dawn KR, Robbins DC, Ratner RE. Impact of computer-generated personalized goals on HbA1c. Diabetes Care (2002) 25: 2
  • Porterfield DS, Kinsinger L. Quality of care for uninsured patients with diabetes in a rural area. Diabetes Care (2002) 25: 319
  • Powers SW, Byars KC, Mitchell MJ, Patton SR, Standiford DA, Dolan LM. Parent report of mealtime behavior and parenting stress in young children with type 1 diabetes and in healthy control subjects. Diabetes Care (2002) 25: 313
  • Prasad S, Jones WA, Jones K, Kamath GG, Bowen-Jones D, Phillips RP. Does opportunistic screening for diabetic retinopathy result in timely and appropriate referral?. Pract Diab Int (2001) 18: 265
  • Richardson T, Kerr D. Digital imaging for the follow-up of patients with established diabetic retinopathy. Pract Diab Int (2002) 19: 15
  • Rickheim PL, Flader JL, Weaver TW, Kendall DM. Assessment of group versus individual diabetes education: A randomized study. Diabetes Care (2002) 25: 269
  • Rohlfing CL, England JD, Wiedmeyer HM, Tennill A, Little RR, Goldstein DE. Defining the relationship between plasma glucose and HbA1c: Analysis of glucose profiles and HbA1c in the Diabetes Control and Complications Trial. Diabetes Care (2002) 25:275
  • Rose M, Fliege H, Hildebrandt M, Schirop T, Klapp BF. The network of psychological variables in patients with diabetes and their importance for quality of life and metabolic control. Diabetes Care (2002) 25: 35
  • Surwit RS, Van Tilburg MAL, Zucker N, McCaskill CC, Parekh P, Feinglos MN, Edwards CL, Williams P, Lane JD. Stress management improves long-term glycemic control in type 2 diabetes. Diabetes Care (2002) 25: 30
  • Woodward A, Groves T, Wallymahamed M, Wilding JP, Gill GV. Attaining UKPDS management targets in type 2 diabetes: Failures and difficulties. Pract Diab Int (2001) 18: 307
  • c) Drug therapy
  • Bertuglia S, Giusti A, Fedele S, Picano E. Glucose-insulin-potassium treatment in combination with dipyridamole inhibits ischaemia-reperfusion-induced damage. Diabetologia (2001) 44: 2165
  • Blomgren KB, Sundstrom A, Steineck G, Wiholm BE. Obesity and treatment of diabetes with glyburide may both be risk factors for acute pancreatitis. Diabetes Care (2002) 25: 298
  • Ciaraldi TP, Kong APS, Chu NV, Kim DD, Baxi S, Loviscach M, Plodkowski R, Reitz R, Caulfield M, Mudaliar S, Henry RR. Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects. Diabetes (2002) 51: 30
  • Croxson SCM, McConvey R, Molodynski L. Profound hypoglycaemia and cognitive impairment (Case Report). Pract Diab Int (2001) 18: 315
  • De Galan BE, Tack CJ, Lenders JW, Pasman JW, Elving LD, Russel FG, Lutterman JA, Smits P. Theophylline improves hypoglycemia unawareness in type 1 diabetes. Diabetes (2002) 51: 790
  • Dea MK, Hamilton-Wessler M, Ader M, Moore D, Schaffer L, Loftager M, Volund A, Bergman RN. Albumin binding of acylated insulin (NN304) does not deter action to stimulate glucose uptake. Diabetes (2002) 51: 762
  • Erdman DM, Cook CB, Greenlund KJ, Giles WH, El Kebbi I, Ryan GJ, Gallina DL, Ziemer DC, Dunbar VG, Phillips LS. The impact of outpatient diabetes management on serum lipids in urban African-Americans with type 2 diabetes. Diabetes Care (2002) 25: 9
  • Jeandidier N, Boullu S, Busch-Brafin MS, Chabrier G, Sapin I, Gasser F, Pinget M. Comparison of antigenicity of Hoechst 21 PH insulin using either implantable intraperitoneal pump or subcutaneous external pump infusion in type 1 diabetic patients. Diabetes Care (2002)25: 84
  • Jones KL, Arslanian S, Peterokova VA, Park JS, Tomlinson M. Effect of metformin in pediatric patients with type 2 diabetes: A randomized controlled trial. Diabetes Care (2002) 25: 89
  • Juhl CB, Hollingdal M, Sturis J, Jakobsen G, Agerso H, Veldhuis J, Porksen N, Schmitz O. Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes. Diabetes (2002) 51:424
  • Katayama S, Kikkawa R, Isogai S, Sasaki N, Matsuura N, Tajima N, Urakami T, Uchigata Y, Ohashi Y. Effect of captopril or imidapril on the progression of diabetic nephropathy in Japanese with type 1 diabetes mellitus: A randomized controlled study (JAPAN-IDDM). Diabetes Res Clin Pract (2002) 55: 113
  • Kim YB, Ciaraldi TP, Kong A, Kim D, Chu N, Mohideen P, Mudaliar S, Henry RR, Kahn BB. Troglitazone but not metformin restores insulin-stimulated phosphoinositide 3-kinase activity and increases p110β protein levels in skeletal muscle of type 2 diabetic subjects. Diabetes (2002) 51: 443
  • Lamotte M, Annemans L, Lefever A, Nechelput M, Masure J. A health economic model to assess the long-term effects and cost-effectiveness of orlistat in obese type 2 diabetic patients. Diabetes Care (2002) 25: 303
  • Mayerson AB, Hundal RS, Dufour S, Lebon V, Befroy D, Cline GW, Enocksson S, Inzucchi SE, Shulman GI, Petersen KF. The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes (2002) 51: 797
  • Miyazaki Y, Glass L, Triplitt C, Matsuda M, Cusi K, Mahankali A, Mahankali S, Mandarino LJ, De Fronzo RA. Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in type 2 diabetic patients. Diabetologia (2001) 44: 2210
  • Pomero F, Min AM, La Selva M, Allione A, Molinatti GM, Porta M. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol (2001) 38: 135
  • Pontiroli AE. EMEA extends indications for metformin. A decision that relies on evidence-based medicine (Commentary). Acta Diabetol (2001) 38: 151
  • Pratipanawatr T, Cusi K, Ngo P, Pratipanawatr W, Mandarino LJ, De Fronzo RA. Normalization of plasma glucose concentration by insulin therapy improves insulin-stimulated glycogen synthesis in type 2 diabetes. Diabetes (2002) 51: 462
  • Ryan AS, Nicklas BJ, Berman DM. Hormone replacement therapy, insulin sensitivity, and abdominal obesity in postmenopausal women. Diabetes Care (2002) 25: 127
  • Schmitz O, Lund S, Andersen PH, Jonler M, Porsen N. Optimizing insulin secretagogue therapy in patients with type 2 diabetes: A randomized double-blind study with repaglinide. Diabetes Care (2002) 25: 342
  • Scognamiglio R, Avogaro A, De Kreutzenberg SV, Negut C, Palisi M, Bagolin E, Tiengo A. Effects of treatment with sulfonylurea drugs or insulin on ischemia-induced myocardial dysfunction in type 2 diabetes. Diabetes (2002) 51: 808
  • Sewter CP, Blows F, Vidal-Puig A, O'Rahilly S. Regional differences in the response of human pre-adipocytes to PPARγ and RXRα agonists. Diabetes (2002) 51: 718
  • Sinha R, Ismail A, Herbert S, Hoyte R, Gill G. Effect of diet and fenofibrate on lipid and glycaemic control in type 2 diabetes. Pract Diab Int (2001) 18: 269
  • Standeven KF, Ariens RAS, Whitaker P, Ashcroft AE, Weisel JW, Grant PJ. The effect of dimethylbiguanide on thrombin activity, FXIII activation, fibrin polymerization, and fibrin clot formation. Diabetes (2002) 51: 189
  • Ter Braak EWMT, Appelman AMMF, Van der Tweel I, Erkelens D, Van Haeften TW. The sulfonylurea glyburide induces impairment of glucagon and growth hormone responses during mild insulin-induced hypoglycemia. Diabetes Care (2002) 25: 107
  • Vichayanrat A, Ploybutr S, Tunlakit M, Watanakejorn P. Efficacy and safety of voglibose in comparison with acarbose in type 2 diabetic patients. Diabetes Res Clin Pract (2002) 55: 99
  • Wright A, Burden ACF, Paisey RB, Cull CA, Holman RR. Sulfonylurea inadequacy: Efficacy of addition of insulin over 6 years in patients with type 2 diabetes in the UK Prospective Diabetes Study (UKPDS 57). Diabetes Care (2002) 25: 330
  • Yang WS, Jeng CY, Wu TJ, Tanaka S, Funahashi T, Matsuzawa Y, Wang JP, Chen CL, Tai TY, Chuang LM. Synthetic peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care (2002)25: 376
  • Zou MH, Shi CM, Cohen RA. High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H2 receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells. Diabetes (2002) 51: 198
  • d) Economics
  • Bagust A, Hopkinson PK, Maier W, Currie CJ. An economic model of the long-term health care burden of type 2 diabetes. Diabetologia (2001) 44: 2140
  • Ramsey S, Summers KH, Leong SA, Birnbaum HG, Kemner JE, Greenberg P. Productivity and medical costs of diabetes in a large employer population. Diabetes Care (2002) 25: 23
  • Shobhana R, Rao PR, Lavanya A, Williams R, Padma C, Vijay V, Ramachandran A. Costs incurred by families having type 1 diabetes in a developing country: A study from Southern India. Diabetes Res Clin Pract (2002) 55: 45
  • f) Nursing
  • Brown SA, Garcia AA, Kouzekanani K, Garcia AA, Hanis CL. Culturally competent diabetes self-management education for Mexican Americans: The Starr County Border Health Initiative. Diabetes Care (2002) 25: 259
  • Hartley LA. Functional health status of persons with diabetes in a nurse-managed clinic. Diabetes Educator (2002) 28: 106
  • McConville DE, Hamilton EM. Syringe disposal practices and gender differences. Diabetes Educator (2002) 28: 91
  • g) Nutrition
  • Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications (Position Statement). Diabetes Care (2002) 25: 202
  • Plagemann A, Harder T, Franke K, Kohlhoff R. Long-term impact of neonatal breast-feeding on body weight and glucose tolerance in children of diabetic mothers. Diabetes Care (2002) 25: 16
  • Rais-Keeley P. Nutrition interventions in early diabetic renal disease. Diabetes Educator (2002) 28: 62
  • h) Surgery
  • Dixon JB, O'Brien PE. Health outcomes of severely obese type 2 diabetic subjects 1 year after laparoscopic adjustable gastric banding. Diabetes Care (2002) 25: 358
  • Kaushal K, New JP, McDowell D, Young LB, Taylor R, Young RJ. Visual outcome after laser treatment for diabetic retinopathy. Pract Diab Int (2002) 19: 6
  • i) Transplantation
  • Alexander AM, Crawford M, Bertera S, Rudert WA, Takikawa O, Robbins pd, Trucco M. Indoleamine 2,3-dioxygenase expression in transplanted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. Diabetes (2002) 51: 356
  • Biarnes M, Montolio M, Nacher V, Raurell M, Soler J, Montanya E. β-Cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes (2002) 51: 66
  • Krook H, Hagberg A, Zong ZS, Landegren U, Wennberg L, Korsgren O. A distinct Th1 immune response precedes the described Th2 response in islet xenograft rejection. Diabetes (2002) 51: 79
  • Piemonti L, Leone BE, Nano R, Saccani A, Monti P, Maffi P, Bianchi G, Sica A, Peri G, Melzi R, Aldrighetti L, Secchi A, Di Carlo V, Allavena P, Bertuzzi F. Human pancreatic islets produce and secrete MCP-1/CCL2: Relevance in human islet transplantation. Diabetes (2002)51: 55
  • Ritz-Laser B, Oberholzer J, Toso C, Brulhart MC, Zakrzewska K, Ris F, Bucher P, Morel P, Philippe J. Molecular detection of circulating β-cells after islet transplantation. Diabetes (2002) 51: 557
  • 9. Pathology and complications:
  • b) Cardiovascular
  • Byberg L, Zethelius B, McKeigue PM, Lithell HO. Changes in physical activity are associated with changes in metabolic cardiovascular risk factors. Diabetologia (2001) 44: 2134
  • Dolan NC, Liu K, Criqui MH, Greenland P, Guralnik JM, Chan CL, Schneider JR, Mandapat AL, Martin G, McDermott MM. Peripheral artery disease, diabetes, and reduced lower extremity functioning. Diabetes Care (2002) 25: 113
  • Fulesdi B, Limburg M, Olah L, Bereczki D, Csiba L, Kollar J. Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type 1 diabetes mellitus. Acta Diabetol (2001) 38: 107
  • Fusman R, Rotstein R, Elishkewich K, Zeltser D, Cohen S, Kofler M, Avitzour D, Arber N, Berliner S, Shapira I. Image analysis for the detection of increased erythrocyte, leukocyte and platelet adhesiveness/aggregation in the peripheral blood of patients with diabetes mellitus. Acta Diabetol (2001) 38: 129
  • Harris SB, Zinman B, Hanley A, Gittelsohn J, Hegele R, Connelly PW, Shah B, Hux JE. The impact of diabetes on cardiovascular risk factors and outcomes in a native Canadian population. Diabetes Res Clin Pract (2002) 55: 165
  • Hintz KK, Ren J. Prediabetic insulin resistance is not permissive to the development of cardiac resistance to insulin-like growth factor 1 in ventricular myocytes. Diabetes Res Clin Pract (2002) 55: 89
  • Ido Y, Carling D, Ruderman N. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: Inhibition by the AMP-activated protein kinase activation. Diabetes (2002) 51: 159
  • Jarvisalo MJ, Putto-Laurila A, Jartti L, Lehtimaki T, Solakivi T, Ronnemaa T, Raitakari OT. Carotid artery intima-media thickness in children with type 1 diabetes. Diabetes (2002) 51: 498
  • Liang QR, Carlson EC, Donthi RV, Kralik PM, Shen X, Epstein PN. Overexpression of metallothionein reduces diabetic cardiomyopathy. Diabetes (2002) 51: 174
  • Nitenberg A, Ledoux S, Valensi P, Sachs R, Antony I. Coronary microvascular adaptation to myocardial metabolic demand can be restored by inhibition of iron-catalyzed formation of oxygen free radicals in type 2 diabetic patients. Diabetes (2002) 51: 813
  • Pacher P, Liaudet L, Soriano FG, Mabley JG, Szabo E, Szabo C. The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes. Diabetes (2002) 51: 514
  • Panzer C, Lauer MS, Brieke A, Blackstone E, Hoogwerf B. Association of fasting plasma glucose with heart rate recovery in healthy adults: A population-based study. Diabetes (2002) 51: 803
  • Rith-Najarian SJ, Gohdes DM, Shields R, Skipper B, Moore KR, Tolbert B, Raymer T, Acton KJ. Regional variation in cardiovascular disease risk factors among American Indians and Alaska natives with diabetes. Diabetes Care (2002) 25: 279
  • Vincent MA, Dawson D, Clark ADH, Lindner JR, Rattigan S, Clark MG, Barrett EJ. Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow. Diabetes (2002) 51: 42
  • c) Eye disease
  • Henricsson M, Berntorp K, Fernlund P, Sundkvist G. Progression of retinopathy in insulin-treated type 2 diabetic patients. Diabetes Care (2002) 25: 381
  • Porta M, Sjoelie AK, Chaturvedi N, Stevens L, Rottiers R, Veglio M, Fuller JH. Risk factors for progression to proliferate diabetic retinopathy in the EURODIAB Prospective Complications Study. Diabetologia (2001) 44: 2203
  • Shiba T, Yamamoto T, Seki U, Utsugi N, Fujita K, Sato Y, Terada H, Sekihara H, Hagura R. Screening and follow-up of diabetic retinopathy using a new mosaic 9-field fundus photography system. Diabetes Res Clin Pract (2002) 55: 49
  • d) Gestational and fetal
  • Shao JH, Yamashita H, Qiao LP, Draznin B, Friedman JE. Phosphatidylinositol 3-kinase redistribution is associated with skeletal muscle insulin resistance in gestational diabetes mellitus. Diabetes (2002) 51: 19
  • e) Neurological
  • Segel SA, Paramore DS, Cryer PE. Hypoglycemia-associated autonomic failure in advanced type 2 diabetes. Diabetes (2002) 51: 724
  • f) Podiatrical
  • Oyibo SO, Jude EB, Voyatzoglou D, Boulton AJM. Clinical characteristics of patients with diabetic problems: Changing patterns of foot ulcer presentation. Pract Diab Int (2002) 19: 10
  • g) Renal
  • Caramori ML, Kim Y, Huang CM, Fish AJ, Rich SS, Miller ME, Russell G, Mauer M. Cellular basis of diabetic nephropathy. I. Study design and renal structural-functional relationships in patients with long-standing type 1 diabetes. Diabetes (2002) 51: 506
  • Rossing K, Jensen BR, Christensen PK, Parving HH. Dual blockade of the renin-angiotensin system in diabetic nephropathy: A randomized double-blind crossover study. Diabetes Care (2002) 25: 95
  • Sweny SE. Toward a better understanding of diabetic nephropathy. Diabetes Educator (2002) 28: 72
  • 10. Endocrinology & metabolism
  • Bergsten P, Westerlund J, Liss P, Carlsson PO. Primary in vivo oscillations of metabolism in the pancreas. Diabetes (2002) 51: 699
  • Beringue F, Blondeau B, Castellotti MC, Breant B, Czernichow P, Polak M. Endocrine pancreas development in growth-retarded human fetuses. Diabetes (2002) 51: 385
  • Bischof MG, Bernroider E, Krssak M, Krebs M, Stingl H, Nowotny P, Yu CL, Shulman GI, Waldhausl W, Roden M. Hepatic glycogen metabolism in type 1 diabetes after long-term near normoglycemia. Diabetes (2002) 51: 49
  • Blaak EE, Wagenmakers AJM. The fate of [U-13C] palmitate extracted by skeletal muscle in subjects with type 2 diabetes and control subjects. Diabetes (2002) 51: 784
  • Dalle S, Fontes G, Lajoix AD, Le Brigand L, Gross R, Ribes G, Dufour M, Barry L, Le Nguyen D, Bataille D. Miniglucagon (glucagon 19-29): A novel regulator of the pancreatic islet physiology. Diabetes (2002) 51: 406
  • Date Y, Nakazato M, Hashiguchi S, Dezaki K, Mondal MS, Hosoda H, Kojima M, Kangawa K, Arima T, Matsuo H, Yada T, Matsukura S. Ghrelin is present in pancreatic α-cells of humans and rats and stimulates insulin secretion. Diabetes (2002) 51: 124
  • Ek I, Arner P, Ryden M, Holm C, Thorne A, Hoffstedt J, Wahrenberg H. A unique defect in the regulation of visceral fat cell lipolysis in the polycystic ovary syndrome as an early link to insulin resistance. Diabetes (2002) 51: 484
  • Eto K, Yamashita T, Tsubamoto Y, Terauchi Y, Hirose K, Kubota N, Yamashita S, Taka J, Satoh S, Sekihara H, Tobe K, Iino M, Noda M, Kimura S, Kadowaki T. Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca2+] elevation signals. Diabetes (2002) 51: 87
  • Goda K, Sasaki E, Nagata K, Fukai M, Ohsawa N, Hahafusa T. Pancreatic volume in type 1 and type 2 diabetes mellitus. Acta Diabetol (2001) 38: 145
  • Gosmanov AR, Thomason DB. Insulin and isoproterenol differentially regulate mitogen-activated protein kinase-dependent Na+-K+-2Cl- cotransporter activity in skeletal muscle. Diabetes (2002) 51: 615
  • Hawkins M, Gabriely I, Wozniak R, Vilcu C, Shamoon H, Rossetti L. Fructose improves the ability of hyperglycemia per se to regulate glucose production in type 2 diabetes. Diabetes (2002) 51: 606
  • Hoffman RP, Sinkey CA, Dopp JM, Phillips BG. Systemic and local adrenergic regulation of muscle glucose utilization during hypoglycemia in healthy subjects. Diabetes (2002) 51: 734
  • Huang BL, Wu PF, Bowker-Kinley MM, Harris RA. Regulation of pyruvate dehydrogenase kinase expression by peroxisome proliferator-activated receptor-α ligands, glucocorticoids, and insulin. Diabetes (2002) 51: 276
  • Kawasaki T, Akanuma H, Yamanouchi TY. Increased fructose concentrations in blood and urine in patients with diabetes. Diabetes Care (2002) 25: 353
  • Keijzers GB, De Galan BE, Tack CJ, Smits P. Caffeine can decrease insulin sensitivity in humans. Diabetes Care (2002) 25: 364
  • Kim HI, Cha JY, Kim SY, Kim JW, Roh KJ, Seong JK, Lee NT, Choi KY, Kim KS, Ahn YH. Peroxisomal proliferator-activated receptor-γ upregulates glucokinase gene expression in β-cells. Diabetes (2002) 51: 676
  • Kiwanuka E, Barazzoni R, Tessari P. Glucose kinetics and splanchnic uptake following mixed meal ingestion in cirrhotic-diabetic subjects. Diabetes Nutr Metab (2001) 14: 315
  • Krebs M, Krssak M, Bernroider E, Anderwald C, Brehm A, Meyerspeer M, Nowotny P, Roth E, Waldhausl W, Roden M. Mechanism of amino acid-induced skeletal muscle insulin resistance in humans. Diabetes (2002) 51: 599
  • Lawrence MC, Bhatt HS, Easom RA. NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1. Diabetes (2002) 51: 691
  • Matsumoto K, Sera Y, Nakamura H, Ueki Y, Miyake S. Serum concentrations of soluble adhesion molecules are related to degree of hyperglycemia and insulin resistance in patients with type 2 diabetes mellitus. Diabetes Res Clin Pract (2002) 55: 131
  • McCarthy AD, Etcheverry SB, Cortizo AM. Effect of advanced glycation endproducts on the secretion of insulin-like growth factor-1 and its binding proteins: Role in osteoblast development. Acta Diabetol (2001) 38: 113
  • Mittelman SD, Van Citters GW, Kirkman EL, Bergman RN. Extreme insulin resistance of the central adipose depot in vivo. Diabetes (2002) 51: 755
  • Moens K, Berger V, Ahn JM, Van Schravendijk C, Hruby VJ, Pipeleers D, Schuit F. Assessment of the role of interstitial glucagon in the acute glucose secretory responsiveness of in situ pancreatic β-cells. Diabetes (2002) 51: 669
  • Munro S, Cuthbertson DJR, Cunningham J, Sales M, Cohen PTW. Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit GL of liver. Diabetes (2002) 51: 591
  • Mur C, Valverde AM, Kahn CR, Benito M. Increased insulin sensitivity in IGF-I receptor-deficient brown adipocytes. Diabetes (2002) 51: 743
  • Nakagami T, Qiao Q, Tuomilehto J, Balkau B, Carstensen B, Tajima N, Iwamoto Y, Borch-Jonsen K. The fasting plasma glucose cut-point predicting a diabetic 2h OGTT glucose level depends on the phenotype. Diabetes Res Clin Pract (2002) 55: 35
  • Ozaki K, Okubo M, Mori H, Mito K, Hara H, Kohno N. Decreased insulin secretion and dyslipidemia coexist in subjects with impaired fasting glucose. Diabetes Res Clin Pract (2002) 55: 159
  • Persaud SJ, Roderigo-Milne HM, Squires PE, Sugden D, Wheeler-Jones CPD, Marsh PJ, Belin VD, Luther MJ, Jones PM. A key role for β-cell cytosolic phospholipase A2 in the maintenance of insulin stores but not in the initiation of insulin secretion. Diabetes (2002)51: 98
  • Pessler D, Rudich A, Bashan N. Oxidative stress impairs nuclear proteins binding to the insulin responsive element in the GLUT4 promoter. Diabetologia (2001) 44: 2156
  • Rolland JF, Henquin JC, Gilon P. Feedback control of the ATP-sensitive K+ current by cytosolic Ca2+ contributes to oscillations of the membrane potential in pancreatic β-cells. Diabetes (2002) 51: 376
  • Rooman I, Lardon J, Bouwens L. Gastrin stimulates β-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue. Diabetes (2002) 51: 686
  • Shah P, Vella A, Basu A, Basu R, Adkins A, Schwenk WF, Johnson CM, Nair KS, Jensen MD, Rizza RA. Effects of free fatty acids and glycerol on splanchnic glucose metabolism and insulin extraction in nondiabetic humans. Diabetes (2002) 51: 301
  • Smih F, Rouet P, Lucas S, Mairal A, Sengenes C, Lafontan M, Vaulont S, Casado M, Langin D. Transcriptional regulation of adipocyte hormone-sensitive lipase by glucose. Diabetes (2002) 51: 293
  • Tanizawa Y, Nakai K, Sasaki T, Anno T, Ohta Y, Inoue H, Matsuo K, Koga M, Furukawa S, Oka Y. Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: Identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase. Diabetes (2002) 51: 712
  • Thong FSL, Derave W, Kiens B, Graham TE, Urso B, Wojtaszewski JFP, Hansen BF, Richter EA. Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise. Diabetes (2002) 51: 583
  • Van Eylen F, Horta OD, Barez A, Kamagate A, Flatt PR, Macianskiene R, Mubagwa K, Herchuelz A. Overexpression of the Na/Ca exchanger shapes stimulus-induced cytosolic Ca2+ oscillations in insulin-producing BRIN-BD11 cells. Diabetes (2002) 51: 366
  • Vecchione C, Maffei A, Colella S, Aretini A, Poulet R, Frati G, Gentile MT, Fratta L, Trimarco V, Trimarco B, Lembo G. Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway. Diabetes (2002) 51: 168
  • Yamagata K, Nammo T, Moriwaki M, Ihara A, Iizuka K, Yang Q, Satoh T, Li M, Uenaka R, Okita K, Iwahashi H, Zhu Q, Cao Y, Imagawa A, Tochino Y, Hanafusa T, Miyagawa J, Matsuzawa Y. Overexpression of dominant-negative mutant hepatocyte nuclear factor-1α in pancreatic β-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced β-cell proliferation, and diabetes. Diabetes (2002) 51: 114
  • 11. Experimental studies
  • Adams AB, Shirasugi N, Durham MM, Strobert E, Anderson D, Rees P, Cowan S, Xu HY, Blinder Y, Cheung M, Hollenbaugh D, Kenyon NS, Pearson TC, Larsen CP. Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. Diabetes (2002)51: 265
  • Aschenbach WG, Hirshman MF, Fujii N, Sakamoto K, Howlett KF, Goodyear LJ. Effect of AICAR treatment on glycogen metabolism in skeletal muscle. Diabetes (2002) 51: 567
  • Baran K, Preston E, Wilks D, Cooney GJ, Kraegen EW, Sainsbury A. Chronic central melanocortin-4 receptor antagonism and central neuropeptide-Y infusion in rats produce increased adiposity by divergent pathways. Diabetes (2002) 51: 152
  • Briaud I, Kelpe CL, Johnson LM, Tran POT, Poitout V. Differential effects of hyperlipidemia on insulin secretion in islets of Langerhans from hyperglycemic versus normoglycemic rats. Diabetes (2002) 51: 662
  • Carpenter L, Cordery D, Biden TJ. Inhibition of protein kinase C delta protects rat INS-1 cells against interleukin-1β and streptozotocin-induced apoptosis. Diabetes (2002) 51: 317
  • Correia MLG, Haynes WG, Rahmouni K, Morgan DA, Sivitz WI, Mark AL. The concept of selective leptin resistance: Evidence from agouti yellow obese mice. Diabetes (2002) 51: 439
  • Dong HJ, Altomonte J, Morral N, Meseck M, Thung SN, Woo SLC. Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats. Diabetes (2002) 51: 130
  • El Salhy M. Gastric emptying in an animal model of human diabetes type 1: Relation to endocrine cells. Acta Diabetol (2001) 38: 139
  • Fiedler M, Zierath JR, Selen G, Wallberg-Henriksson H, Liang Y, Sakariassen KS. 5-Amino-imidazole-4-carboxy-amide-1-β-D-ribofuranoside treatment ameliorates hyperglycaemia and hyperinsulinaemia but not dyslipidaemia in KKAy-CETP mice. Diabetologia (2001) 44: 2180
  • Fornoni A, Striker LJ, Zheng F, Striker GE. Reversibility of glucose-induced changes in mesangial cell extracellular matrix depends on the genetic background. Diabetes (2002) 51: 499
  • Franch J, Knudsen J, Ellis BA, Pedersen PK, Cooney GJ, Jensen J. Acyl-CoA binding protein expression is fiber type-specific and elevated in muscles from the obese insulin-resistant Zucker rat. Diabetes (2002) 51: 449
  • Grattan M, Mi QS, Meagher C, Delovitch TL. Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice. Diabetes (2002) 51: 215
  • Gunawardana SC, Sharp GWG. Intracellular pH plays a critical role in glucose-induced time-dependent potentiation of insulin release in rat islets. Diabetes (2002) 51: 105
  • Gurr W, Yavari R, Wen L, Shaw M, Mora C, Christa L, Sherwin RS. A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice. Diabetes (2002) 51: 339
  • Hamilton-Wessler M, Ader M, Dea MK, Moore D, Loftager M, Markussen J, Bergman RN. Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: Evidence for passive diffusion. Diabetes (2002) 51: 574
  • Han DM, Xu XM, Pastori RL, Ricordi C, Kenyon NS. Elevation of cytotoxic lymphocyte gene expression is predictive of islet allograft rejection in nonhuman primates. Diabetes (2002) 51: 562
  • Hernandez-Sanchez C, Rubio E, Serna J, De la Rosa EJ, De Pablo F. Unprocessed proinsulin promotes cell survival during neurulation in the chick embryo. Diabetes (2002) 51: 770
  • Hinke SA, Gelling RW, Pederson RA, Manhart S, Nian C, Demuth HU, McIntosh CHS. Dipeptidyl peptidase IV-resistant [D-Ala2] glucose-dependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats. Diabetes (2002) 51:652
  • Howlett KF, Sakamoto K, Hirshman MF, Aschenbach WG, Dow M, White MF, Goodyear LJ. Insulin signaling after exercise in insulin receptor substrate-2-deficient mice. Diabetes (2002) 51: 479
  • Imamura H, Morimoto I, Tanaka Y, Hashimoto O, Kanda K, Yamashita S, Eto S. Regulation of glucose transporter 1 expression by gliclazide in rat L6 myoblasts. Diabetes Nutr Metab (2001) 14: 308
  • Kim BM, Han YM, Shin YJ, Min BH, Park IS. Clusterin expression during regeneration of pancreatic islet cells in streptozotocin-induced diabetic rats. Diabetologia (2001) 44: 2192
  • Kim YK, Lee MS, Son SM, Kim IJ, Lee WS, Rhim BY, Hong KW, Kim CD. Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes. Diabetes (2002) 51: 522
  • Kishi M, Tanabe J, Schmelzer JD, Low PA. Morphometry of dorsal root ganglion in chronic experimental diabetic neuropathy. Diabetes (2002) 51: 819
  • Mei J, Holst LS, Landstrom TR, Holm C, Brindley D, Manganiello V, Degerman E. C2-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes. Diabetes (2002) 51: 631
  • Mithieux G, Guignot L, Bordet JC, Wiernsperger N. Intrahepatic mechanisms underlying the effect of metformin in decreasing basal glucose production in rats fed a high-fat diet. Diabetes (2002) 51: 139
  • Obici S, Feng ZH, Morgan Y, Stein D, Karkanias G, Rossetti L. Central administration of oleic acid inhibits glucose production and food intake. Diabetes (2002) 51: 271
  • Rabinovitch A, Suarez-Pinzon WL, Shapiro AMJ, Rajotte RV, Power R. Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice. Diabetes (2002) 51: 638
  • Reifsnyder PC, Leiter EH. Deconstructing and reconstructing obesity-induced diabetes (diabesity) in mice. Diabetes (2002) 51: 825
  • Riu E, Mas A, Ferre T, Pujol A, Gros L, Otaegui P, Montoliu L, Bosch F. Counteraction of type 1 diabetic alterations by engineering skeletal muscle to produce insulin: Insights from transgenic mice. Diabetes (2002) 51: 704
  • Sakurai T, Yang B, Takata T, Yokono K. Synaptic adaptation to repeated hypoglycemia depends on the utilization of monocarboxylates in guinea pig hippocampal slices. Diabetes (2002) 51: 430
  • Scott FW, Rowsell P, Wang GS, Burghardt K, Kolb H, Flohe S. Oral exposure to diabetes-promoting food or immunomodulators in neonates alters gut cytokines and diabetes. Diabetes (2002) 51: 73
  • Serradas P, Goya L, Lacorne M, Gangnerau MN, Ramos S, Alvarez C, Pascual-Leone AM, Portha B. Fetal insulin-like growth factor-2 production is impaired in the GK rat model of type 2 diabetes. Diabetes (2002) 51: 392
  • Shiota M, Moore MC, Galassetti P, Monohan M, Neal DW, Shulman GI, Cherrington AD. Inclusion of low amounts of fructose with an intraduodenal glucose load markedly reduces postprandial hyperglycemia and hyperinsulinemia in the conscious dog. Diabetes (2002) 51: 469
  • Sindelar DK, Mystkowski P, Marsh DJ, Palmiter RD, Schwartz MW. Attenuation of diabetic hyperphagia in neuropeptide Y-deficient mice. Diabetes (2002) 51: 778
  • Tack I, Elliot SJ, Potier M, Rivera A, Striker GE, Striker LJ. Autocrine activation of the IGF-I signalling pathway in mesangial cells isolated from diabetic NOD mice. Diabetes (2002) 51: 182
  • Webb GC, Akbar MS, Zhao CJ, Swift HH, Steiner DF. Glucagon replacement via micro-osmotic pump corrects hypoglycemia and α-cell hyperplasia in prohormone convertase 2 knockout mice. Diabetes (2002) 51: 398
  • Wojtaszewski JFP, Jorgensen SB, Hellsten Y, Hardie DG, Richter EA. Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-ribosied on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle. Diabetes (2002) 51:284
  • 12. Diagnosis and techniques
  • Lock JP, Szuts EZ, Malomo KJ, Anagnostopoulos A. Whole-mood glucose testing at alternate sites: Glucose values and hematocrit of capillary blood drawn from fingertip and forearm. Diabetes Care (2002) 25: 337
  • Maran A, Crepaldi C, Tiengo A, Grassi G, Vitali E, Pagano G, Bistoni S, Calabrese G, Santeusanio F, Leonetti F, Ribaudo M, Di Mario U, Annuzzi G, Genovese S, Riccardi G, Previti M, Cucinotta D, Giorgino F, Bellomo A, Giorgino R, Poscia A, Varalli M. Continuous subcutaneous glucose monitoring in diabetic patients: A multicenter analysis. Diabetes Care (2002) 25: 347
  • Virtanen KA, Peltoniemi P, Marjamaki P, Asola M, Strindberg L, Parkkola R, Huupponen R, Knuuti J, Lonnroth P, Nuutila P. Human adipose tissue glucose uptake determined using [18F]-fluoro-deoxy-glucose ([18F]FDG and PET in combination with microdialysis. Diabetologia (2001)44: 2171