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Research Article
A report from the international consensus on diagnosing and treating the infected diabetic foot†
Article first published online: 29 APR 2004
DOI: 10.1002/dmrr.453
Copyright © 2004 John Wiley & Sons, Ltd.
Issue
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Diabetes/Metabolism Research and Reviews
Supplement: The Diabetic Foot: Proceedings of the Fourth International Symposium on the Diabetic Foot, 22–24 May 2003, Noordwijkerhout, The Netherlands
Volume 20, Issue Supplement 1, pages S68–S77, May/June 2004
Additional Information
How to Cite
Lipsky, B. A. (2004), A report from the international consensus on diagnosing and treating the infected diabetic foot. Diabetes/Metabolism Research and Reviews, 20: S68–S77. doi: 10.1002/dmrr.453
- †
Publication History
- Issue published online: 29 APR 2004
- Article first published online: 29 APR 2004
- Manuscript Accepted: 6 JAN 2004
- Manuscript Revised: 12 DEC 2003
- Manuscript Received: 11 DEC 2003
- Abstract
- Article
- References
- Cited By
Keywords:
- diabetic foot infections;
- osteomyelitis;
- antibiotic therapy;
- wound cultures;
- guidelines;
- foot complications
Abstract
In persons with diabetes, foot infection, that is, invasion and multiplication of microorganisms in tissues accompanied by tissue destruction or a host inflammatory response, usually begins with skin trauma or ulceration 1. While most foot infections remain superficial, they can spread to subcutaneous tissues, including muscle, joints, and bone. Many diabetic foot ulcers eventuate in an amputation; infection plays a role in approximately 60% of cases 2–4. Neuropathy is the main factor leading to skin breaks, while arterial perfusion largely affects infection outcome. Among the factors predisposing diabetic patients to foot infections are ill-defined immunological perturbations 5, 6; foot anatomy may foster proximal spread of infection and ischemic necrosis 7, 8. Copyright © 2004 John Wiley & Sons, Ltd.