Drug Testing and Analysis

Cover image for Vol. 5 Issue 9-10

Special Issue: Case reports in forensic toxicology

September-October 2013

Volume 5, Issue 9-10

Pages i–i, 723–807

Issue edited by: Frank Musshoff

  1. Cover picture

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. Cover Picture (page i)

      Article first published online: 21 OCT 2013 | DOI: 10.1002/dta.1572

      Thumbnail image of graphical abstract
  2. Editorial

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. You have free access to this content
  3. Research articles

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. A rare case of serial killing by poisoning (pages 725–729)

      Erkki Vuori, Anna Pelander, Ilpo Rasanen, Mikko Juote and Ilkka Ojanperä

      Article first published online: 24 APR 2013 | DOI: 10.1002/dta.1480

      Thumbnail image of graphical abstract

      A case of serial killing by poisoning by a practical nurse is reported. In the absence of ordinary post-mortem toxicology samples, a special kind of evidence, paraffin-embedded liver tissue samples (originally taken for histology at autopsy), was successfully recovered in two cases and analyzed for drugs. In all five homicides, drugs not prescribed for the patient were detected, including digoxin, dixyrazine, citalopram, venlafaxine, and benzodiazepines (diazepam, chlordiazepoxide, temazepam and oxazepam).

  4. Correspondence case reports

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
  5. Short communications

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. Nurse induced respiratory depression by succinylcholine – the ‘hero syndrome’ (pages 741–744)

      F. Musshoff, U. Kuepper and B. Madea

      Article first published online: 15 MAY 2013 | DOI: 10.1002/dta.1490

      Thumbnail image of graphical abstract

      A nurse administered succinylcholine (SUX) and gave first aid in the therapy of unexpected respiratory depression. SUX and succinylmonocholine (SMC) were found in plasma and urine. She wanted to present herself spectacularly as the first and decisive rescuer.

  6. Correspondence case reports

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. Desalkylflurazepam found in patients’ samples after high-dose midazolam treatment (pages 745–747)

      Susanne Vogt, Jürgen Kempf, Jürgen Buttler, Volker Auwärter and Wolfgang Weinmann

      Article first published online: 24 MAY 2013 | DOI: 10.1002/dta.1484

  7. Research articles

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. An unusual case of risperidone instability in a fatality presenting an analytical and interpretative challenge (pages 748–752)

      Kerry Taylor and Simon Elliott

      Article first published online: 19 JUL 2013 | DOI: 10.1002/dta.1503

      Thumbnail image of graphical abstract

      This paper describes the detection and characterisation of ring scission breakdown products of risperidone and hydroxy metabolite in post mortem blood and urine as part of a toxicological investigation into an unexpected death.

    2. Quantification of aconitine in post-mortem specimens by validated liquid chromatography-tandem mass spectrometry method: Three case reports on fatal ‘monkshood’ poisoning (pages 753–762)

      Wolfgang Bicker, Fabio Monticelli, Andreas Bauer, Gabriele Roider and Thomas Keller

      Article first published online: 10 JUN 2013 | DOI: 10.1002/dta.1501

      Thumbnail image of graphical abstract

      Three cases where suicidal ingestion of Aconitum napellus L. (‘monkshood’) was supposed are presented. Aconitine was quantified in eight different post-mortem matrices by a validated LC-MS/MS method. Together with concomitant circumstances the analytical data provided compelling evidence for acute Aconitum poisoning as being the cause of death.

    3. Body fluid and tissue analysis using filter paper sampling support prior to LC-MS/MS: Application to fatal overdose with colchicine (pages 763–772)

      Estelle Lauer, Christèle Widmer, François Versace, Christian Staub, Patrice Mangin, Sara Sabatasso, Marc Augsburger and Julien Déglon

      Article first published online: 16 MAY 2013 | DOI: 10.1002/dta.1496

      Thumbnail image of graphical abstract

      Although filter paper is usually employed for Dried Blood Spots, we report here the extension of this alternative sampling support to the analysis of other body fluids and tissues collected after a fatal overdose with colchicine. The developed LC-MS/MS platform, including automated 96-well extraction of filter paper, represents a rapid and versatile approach for drug determination in multiple forensic media.

  8. Correspondence case reports

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. A fatal case involving a caffeine-containing fat burner (pages 773–776)

      Ricarda Jantos, Kirsten Marion Stein, Christa Flechtenmacher and Gisela Skopp

      Article first published online: 9 MAY 2013 | DOI: 10.1002/dta.1485

    2. Chloroquine and diazepam for her last sleep (pages 777–780)

      Sarah Hangartner, Sebastian Eggert, Franz Dussy, Daniel Wyler and Thomas Briellmann

      Article first published online: 12 JUL 2013 | DOI: 10.1002/dta.1509

    3. Dextromethorphan/levomethorphan issues in a case of opiate overdose (pages 781–784)

      Federica Bortolotti, Anna Bertaso, Rossella Gottardo, Giacomo Musile and Franco Tagliaro

      Article first published online: 21 OCT 2013 | DOI: 10.1002/dta.1577

    4. Acute intoxication by synthetic cannabinoids – Four case reports (pages 790–794)

      Maren Hermanns-Clausen, Stefan Kneisel, Melanie Hutter, Bela Szabo and Volker Auwärter

      Article first published online: 20 MAY 2013 | DOI: 10.1002/dta.1483

  9. Research articles

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. Detection of diabetic metabolism disorders post-mortem – forensic case reports on cause of death hyperglycaemia (pages 795–801)

      C. Hess, K. Wöllner, F. Musshoff and B. Madea

      Article first published online: 25 APR 2013 | DOI: 10.1002/dta.1479

      Thumbnail image of graphical abstract

      Six death cases caused by diabetic coma are described with special focus on biochemical (and histological) findings. Estimations of glucose concentrations in vitreous humour or cerebrospinal fluid and of ketone bodies in blood or other matrices is obligatory while measurements of HbA1c, fructosamine or anhydroglucitol can only provide additional information on the long-term adjustment of diabetes in the deceased.

  10. Short communications

    1. Top of page
    2. Cover picture
    3. Editorial
    4. Research articles
    5. Correspondence case reports
    6. Short communications
    7. Correspondence case reports
    8. Research articles
    9. Correspondence case reports
    10. Research articles
    11. Short communications
    1. Determination of hypoglycaemia induced by insulin or its synthetic analogues post mortem (pages 802–807)

      C. Hess, B. Madea, T. Daldrup and F. Musshoff

      Article first published online: 11 JUL 2013 | DOI: 10.1002/dta.1500

      Thumbnail image of graphical abstract

      Two cases of an insulin-induced hypoglycaemia are presented, one injection with human insulin, another case with self-injection of Insulin lispro. The possibility of detection of insulin and its synthetic analogues after pre-extraction with methanol and immunopurification with magnetic beads and quantification by LC/MS-MS in serum, at the injection site, in vitreous humor and organs is presented.

SEARCH

SEARCH BY CITATION