Tales of regeneration in zebrafish
Article first published online: 9 JAN 2003
Copyright © 2003 Wiley-Liss, Inc.
Special Issue: Regeneration Special Issue
Volume 226, Issue 2, pages 202–210, February 2003
How to Cite
Poss, K. D., Keating, M. T. and Nechiporuk, A. (2003), Tales of regeneration in zebrafish. Dev. Dyn., 226: 202–210. doi: 10.1002/dvdy.10220
- Issue published online: 28 JAN 2003
- Article first published online: 9 JAN 2003
- Manuscript Accepted: 25 SEP 2002
- Manuscript Received: 15 AUG 2002
- wound healing;
Complex tissue regeneration involves exquisitely coordinated proliferation and patterning of adult cells after severe injury or amputation. Certain lower vertebrates such as urodele amphibians and teleost fish have a greater capacity for regeneration than mammals. However, little is known about molecular mechanisms of regeneration, and cellular mechanisms are incompletely defined. To address this deficiency, we and others have focused on the zebrafish model system. Several helpful tools and reagents are available for use with zebrafish, including the potential for genetic approaches to regeneration. Recent studies have shed light on the remarkable ability of zebrafish to regenerate fins. Developmental Dynamics 226:202–210, 2003. © 2003 Wiley-Liss, Inc.