SEARCH

SEARCH BY CITATION

REFERENCES

  • Ahlgren U, Jonsson J, Edlund H. 1996. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in PDX1/IPF1-deficient mice. Development 122: 14091416.
  • Apelqvist A, Ahlgren U, Edlund H. 1997. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas. Curr Biol 7: 801804.
  • Apelqvist Å, Li H, Sommer L. 1999. Notch-signalling controls pancreatic cell differentiation. Nature 400: 877881.
  • Beatus P, Lendahl U. 1998. Notch and neurogenesis. J Neurosci Res 54: 125136.
  • Bellusci S, Grindley J, Emoto H, Itoh N, Hogan B. 1997. Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124: 48674878.
  • Bhushan A, Itoh N, Kato S, Thiery JP, Czernichow P, Bellusci S, Scharfmann R. 2001. Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 128: 51095117.
  • Briscoe J, Sussel L, Serup P, Hartigan-O'Connor D, Jessell TM, Rubenstein JL, Ericson J. 1999. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature 398: 622627.
  • Celli G, LaRochelle WJ, Mackem S, Sharp R, Merlino G. 1998. Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J 17: 16421655.
  • Chiang MK, Melton DA. 2003. Single-cell transcript analysis of pancreas development. Dev Cell 4: 383393.
  • Donoviel DB, Donoviel MS, Fan E, Hadjantonakis A, Bernstein A. 1998. Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene. Mech Dev 78: 203207.
  • Edlund H. 1998. Transcribing pancreas. Diabetes 47: 18171823.
  • Edlund H. 2002. Pancreatic organogenesis- developmental mechanisms and implications for therapy. Nat Rev Genet 3: 524532.
  • Elghazi L, Cras-Meneur C, Czernichow P, Scharfmann R. 2002. Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation. Proc Natl Acad Sci U S A 99: 38843889.
  • Faux CH, Turnley AM, Epa R, Cappai R, Bartlett PF. 2001. Interactions between fibroblast growth factors and Notch regulate neuronal differentiation. J Neurosci 21: 55875596.
  • Gradwohl G, Dierich A, LeMeur M, Guillemot F. 2000. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 9: 7160771611.
  • Grant B, Greenwald I. 1997. Structure, function, and expression of SEL-1, a negative regulator of LIN-12 and GLP-1 in C. elegans. Development 124: 637644.
  • Hart AW, Baeza N, Apelqvist A, Edlund H. 2000. Attenuation of FGF-signalling in mouse β-cells leads to diabetes. Nature 408: 864868.
  • Hogan B, Constantini F, Lacey E. 1994. In manipulating the mouse embryo: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Press.
  • Jensen J, Pedersen EE, Galante P. 2000. Control of endodermal endocrine development by Hes-1. Nat Genet 24: 3644.
  • Kato S, Sekine K. FGF-FGFR signaling in vertebrate organogenesis. 1999. Cell Mol Biol 45: 631638.
  • Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, Wright CV. 2002. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet 32: 128134.
  • Krapp A, Knofler M, Ledermann B, Burki K, Berney C, Zoerkler N, Hagenbuchle O, Wellauer PK. 1998. The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev 12: 37523763.
  • Lewis J. 1996. Neurogenic genes and vertebrate neurogenesis. Curr Opin Neurobiol 6: 310.
  • Li H, Edlund H. 2001. Persistent expression of Hlxb9 in the pancreatic epithelium impairs pancreatic development. Dev Biol 240: 247253.
  • Miralles F, Czernichow P, Ozaki K, Itoh N, Scharfmann R. 1999. Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas. Proc Natl Acad Sci U S A 96: 62676272.
  • Ohlsson H, Karlsson K, Edlund T. 1993. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12: 42514259.
  • Ohuchi H, Hori Y, Yamasaki M, Harada H, Sekine K, Kato S, Itoh N. 2000. FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development. Biochem Biophys Res Commun 277: 643649.
  • Revest JM, Spencer-Dene B, Kerr K, De Moerlooze L, Rosewell I, Dickson C. 2001. Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4. Dev Biol 231: 4762.
  • Ryan EA, Lakey JR, Rajotte RV, Korbutt GS, Kin T, Imes S, Rabinovitch A, Elliott JF, Bigam D, Kneteman NM, Warnock GL, Larsen I, Shapiro AM. 2001. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 50: 710719.
  • Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M. 2000. Homeobox gene Nkx6. 1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. Development 127: 55335540.
  • Schwitzgebel VM, Scheel DW, Conners JR, Kalamaras J, Lee JE, Anderson DJ, Sussel L, Johnson JD, German MS. 2000. Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 127: 35333542.
  • Selander L, Edlund H. 2002. Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas. Mech Dev 113: 189192.
  • Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV. 2000. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343: 230238.
  • Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS. 1998. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 125: 22132221.
  • Szebenyi G, Fallon JF. 1999. Fibroblast growth factors as multifunctional signaling factors. Int Rev Cytol 185: 45106.
  • Thor S, Ericson J, Brännström T, Edlund T. 1991. The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat. Neuron 7: 881889.