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  • Abdelilah S, Mountcastle-Shah E, Harvey M, Solnica-Krezel L, Schier AF, Stemple DL, Malicki J, Neuhauss SC, Zwartkruis F, Stainier DY, Rangini Z, Driever W. 1996. Mutations affecting neural survival in the zebrafish Danio rerio. Development 123: 217227.
  • Alexander J, Stainier DY, Yelon D. 1998. Screening mosaic F1 females for mutations affecting zebrafish heart induction and patterning. Dev Genet 22: 288299.
  • Alexander J, Rothenberg M, Henry GL, Stainier DYR. 1999. casanova plays an early and essential role in endoderm formation in zebrafish. Dev Biol 215: 343357.
  • Amacher SL, Kimmel CB. 1998. Promoting notochord fate and repressing muscle development in zebrafish axial mesoderm. Development 125: 13971406.
  • Amacher SL, Draper BW, Summers BR, Kimmel CB. 2002. The zebrafish T-box genes no tail and spadetail are required for development of trunk and tail mesoderm and medial floor plate. Development 129: 33113323.
  • Amatruda JF, Shepard J, Stern H, Zon LI. 2002. Zebrafish as a cancer model system. Cancer Cell 1: 229231.
  • Amsterdam A, Burgress S, Golling G, Chen W, Sun Z, Townsend K, Farrington S, Haldi M, Hopkins N. 1999. A large-scale insertional mutagenesis screen in zebrafish. Genes Dev 13: 27132724.
  • Aoki TO, David NB, Minchiotti G, Saint-Etienne L, Dichmeis T, Persico GM, Strahle U, Mourrain P, Rosa FM. 2002. Molecular integration of casanova in the Nodal signalling pathway controlling endoderm formation. Development 129: 275286.
  • Araki I, Brand M. 2001. Morpholino-induced knockdown of fgf8 efficiently phenocopies the acerebellar (ace) phenotype. Genesis 30: 157159.
  • Baier H, Klostermann S, Trowe T, Karlstrom RO, Nusslein-Volhard C, Bonhoeffer F. 1996. Genetic dissection of the retinotectal projection. Development 123: 415425.
  • Baker K, Warren KS, Yellen G, Fishman MC. 1997. Defective “pacemaker” current (Ih) in a zebrafish mutant with a slow heart rate. Proc Natl Acad Sci U S A 94: 45544559.
  • Bamford RN, Roessler E, Burdine RD, Saplakoglu U, de la Cruz J, Splitt M, Towbin J, Bowers P, Marino B, Schier AF, Shen MM, Muenke M, Casey B. 2000. Loss of function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects. Nat Genet 26: 365369.
  • Barbazuk WB, Korf I, Kadavi C, Heyen J, Tate S, Wun E, Bedell JA, McPherson JD, Johnson SL. 2000. The syntenic relationship of the zebrafish and human genomes. Genome Res 10: 13511358.
  • Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, Soults J, Grayzel D, Kroumpouzou E, Traill TA, Leblanc-Straceski J. 1997. Mutations in human TBX5 cause limb and cardiac malformation in Holt-Oram syndrome. Nat Genet 15: 3035.
  • Bauer A, Chauvet S, Huber O, Usseglio F, Rothbacher U, Aragnol D, Kemler R, Pradel J. 2000. Pontin52 and reptin52 function as antagonistic regulators of β-catenin signalling activity. EMBO J 19: 61216130.
  • Bennett CM, Kanki JP, Rhodes J, Liu TX, Paw BH, Kieran MW, Langenau DM, Delahaye-Brown A, Zon LI, Fleming MD, Look AT. 2001. Myelopoiesis in the zebrafish, Danio rerio. Blood 98: 643651.
  • Bisgrove BW, Yost HJ. 2001. Classification of left-right patterning defects in zebrafish, mice, and humans. Am J Med Genet 101: 315323.
  • Bisgrove BW, Essner JJ, Yost HJ. 2000. Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry. Development 127: 35673579.
  • Brand M, Heisenberg C-P, Warga RM, Pelegri F, Karlstrom RO, Beuchle D, Picker A, Jiang Y-J, Furutani-Seiki M, van Eeden FJ, Granato M, Haffter P, Hammerschmidt M, Kane DA, Kelsh RN, Mullins MC, Odenthal J, Nusslein-Volhard C. 1996. Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development 123: 129142.
  • Brokerhoff SE, Hurley JB, Janssen-Bienhold U, Neuhauss SC, Driever W, Dowling JE. 1995. A behavioral screen for isolating zebrafish mutants with visual system defects. Proc Natl Acad Sci U S A 92: 1054510549.
  • Brokerhoff SE, Dowling JE, Hurley JB. 1998. Zebrafish retinal mutants. Vision Res 38: 13351339.
  • Brownlie A, Donovan A, Pratt SJ, Paw BH, Oates AC, Brugnara C, Witkowska HE, Sassa S, Zon LI. 1998. Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anemia. Nat Genet 20: 244250.
  • Brownlie AJ, Hersey C, Oates AC, Paw BH, Falick AM, Witkowska HE, Flint J, Higgs D, Jessen J, Bahary N, Zhu H, Lin S, Zon L. 2003. Characterization of embryonic globin genes of the zebrafish. Developmental Biology 255: 4861.
  • Burns CE, DeBlasio T, Zhou Y, Zhang J, Zon L, Nimer SD. 2002. Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators. Exp Hematol 30: 13811389.
  • Chen J-N, Fishman M. 1996. Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development 122: 38093816.
  • Chen J-N, Haffter P, Odenthal J, Vogelsang E, Brand M, van Eeden FJ, Furutani-Seiki M, Granato M, Hammerschmidt M, Heisenberg C-P, Jiang Y-J, Kane DA, Kelsh RN, Mullins MC, Nusslein-Volhard C. 1996. Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development 123: 293302.
  • Chen W, Burgress S, Hopkins N. 2001. Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity. Development 128: 23852396.
  • Childs S, Weinstein BM, Mohideen MPK, Donohue S, Bonkovsky H, Fishman MC. 2000. Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria. Curr Biol 10: 10011004.
  • Cotter PD, Rucknagel DL, Bishop DF. 1994. X-linked sideroblastic anemia: identification of the mutation in erythroid specific δ-aminolevulinate synthase gene (ALAS2) in the original family described by Cooley. Blood 84: 39153924.
  • David NB, Rosa FM. 2001. Cell autonomous commitment to an endodermal fate and behavior by activation of Nodal signaling. Development 128: 39373947.
  • Detrich HW III, Kieran MW, Chan FY, Barone LM, Yee K, Rundstadler JA, Pratt S, Ransom D, Zon LI. 1995. Intraembryonic hematopoietic cell migration during vertebrate development. Proc Natl Acad Sci U S A 92: 1071310717.
  • Dichmeis T, Mourrain P, Saint-Etienne L, Fischer N, Aanstad P, Clark M, Strahle U, Rosa F. 2001. A crucial component of the endoderm formation pathway CASANOVA is encoded by a novel sox-related gene. Genes Dev 15: 14871492.
  • Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, Zon LI. 2000. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 403: 776781.
  • Donovan A, Brownlie A, Dorschner MO, Zhou Y, Pratt SJ, Paw BH, Phillips RB, Thisse C, Thisse B, Zon LI. 2002. The zebrafish mutant gene chardonnay (cdy) encodes a divalent metal transporter 1 (DMT1). Blood 100: 46554659.
  • Dougan ST, Warga RM, Kane DA, Schier AF, Talbot WS. 2003. The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development 130: 18371851.
  • Driever W, Fishman MC. 1996. The zebrafish: heritable disorders in transparent embryos. J Clin Invest 97: 17881794.
  • Driever W, Solnica-Krezel L, Schier AF, Neuhauss SCF, Malicki J, Stemple DL, Stainier DYR, Zwartkruis F, Abdelilah S, Rangini Z, Belak J, Boggs C. 1996. A genetic screen for mutations affecting embryogenesis in zebrafish. Development 123: 3746.
  • Feldman JL, Concha ML. 2002. Lefty antagonism of squint is essential for normal gastrulation. Curr Biol 12: 21292135.
  • Feldman JL, Stemple DL. 2001. Morpholino phenocopies of sqt, ope, and ntl mutations. Genesis 30: 175177.
  • Gaiano N, Amsterdam A, Kawakami K, Allende M, Becker T, Hopkins N. 1996. Insertional mutagenesis and rapid cloning of essential genes in zebrafish. Nature 383: 829832.
  • Galloway JL, Zon LI. 2003. Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Curr Top Dev Biol 53: 139158.
  • Garrity DM, Childs S, Fishman MC. 2002. The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome. Development 129: 46354645.
  • Gering M, Rodaway AR, Gottgens B, Patient RK, Green AR. 1998. The SCL gene specifies haemangioblast development from early mesoderm. EMBO J 17: 40294045.
  • Gerull B, Gramlich M, Atherton J, McNabb M, Trombitas K, Sasse-Klaassen S, Seidman JG, Seidman C, Granzier H, Labeit S, Frenneaux M, Thierfelder L. 2002. Mutations of TTN, encoding the giant muscle filament Titin, cause familial dilated cardiomyopathy. Nat Genet 30: 201204.
  • Glickman NS, Yelon D. 2002. Cardiac development in zebrafish: coordination of form and function. Cell Dev Biol 13: 507513.
  • Golling G, Amsterdam A, Sun Z, Antonelli M, Maldonado E, Chen W, Burgress S, Haldi M, Artzt K, Farrington S, Lin S-Y, Nissen RM, Hopkins N. 2002. Insertional mutagenesis in zebrafish rapidly identified genes essential for early vertebrate development. Nat Genet 31: 135140.
  • Griffin KJP, Kimelman D. 2002. One-eyed pinhead and spadetail are essential for heart and somite formation. Nat Cell Biol 4: 821825.
  • Gripp KW, Wotton D, Edwards MC, Roessler E, Ades L, Meinechke P, Richieri-Costa A, Zackai EH, Massague J, Muenke M, Elledge SJ. 2000. Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination. Nat Genet 25: 205208.
  • Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF. 1999. The EGF-CFC protein one-eyed pinhead is essential for Nodal signaling. Cell 97: 121132.
  • Guo S, Wilson SW, Cooke S, Chitnis AB, Driever W, Rosenthal A. 1999. Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons. Dev Biol 208: 473487.
  • Guo S, Yamaguchi Y, Schilbach S, Wada T, Lee J, Goddard A, French D, Handa H, Rosenthal A. 2000. A regulator of transcriptional elongation controls vertebrate neuronal development. Nature 408: 366369.
  • Guyon JR, Mosley AN, Zhou Y, O'Brien KF, Sheng X, Chiang K, Davidson AJ, Volinski JM, Zon LI, Kunkel LM. 2003. The dystrophin associated protein complex in zebrafish. Hum Mol Genet 12: 601615.
  • Habeck H, Odenthal J, Walderich B, Maischein H-M, Schulte-Merker S, Tubingen 2000 screen consortium. 2002. Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Curr Biol 12: 14051412.
  • Haffter P, Granato M, Brand M, Mullins MC, Hammerschmidt M, Kane DA, Odenthal J, van Eeden FJ, Jiang Y-J, Heisenberg C-P, Kelsh RN, Furutani-Seiki M, Vogelsang E, Beuchle D, Schach U, Fabian C, Nusslein-Volhard C. 1996. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development 123: 136.
  • Halpern ME, Thisse C, Ho RK, Thisse B, Riggleman B, Trevarrow B, Weinberg ES, Postlewait JH, Kimmel CB. 1995. Cell-autonomous shift from axial to paraxial mesodermal development in zebrafish floating head mutants. Development 121: 42574264.
  • Halpern ME, Hatta K, Amacher SL, Talbot WS, Yan Y-L, Thisse B, Thisse C, Postlethwait JH, Kimmel CB. 1997. Genetic interactions in zebrafish midline development. Dev Biol 187: 154170.
  • Hammerschmidt M, Pelegri F, Mullins MC, Kane DA, Brand M, Heisenberg C-P, Jiang Y-J, Kelsh RN, Odenthal J, Warga RM, Nusslein-Volhard C. 1996. Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. Development 123: 143151.
  • Hansen JD, Strassburger P, Du Pasquier L. 1997. Conservation of a master hematopoietic switch gene during vertebrate evolution: isolation and characterization of Ikaros from teleost and amphibian species. Eur J Immunol 27: 30493058.
  • Hatta K, Kimmel CB, Ho RK, Walker C. 1991. The cyclops mutation blocks specification of the floor plate of the zebrafish central nervous system. Nature 350: 339341.
  • Heasman J. 2002. Morpholino oligos: making sense of antisense. Dev Biol 243: 209214.
  • Henry CA, Urban MK, Dill KK, Merlie JP, Page MF, Kimmel CB, Amacher SL. 2002. Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries. Development 129: 36933704.
  • Herbomel P, Thisse B, Thisse C. 1999. Ontogeny and behaviour of early macrophages in the zebrafish embryo. Development 126: 37353745.
  • Horne-Badovinac S, Lin D, Waldron S, Schwarz M, Mbamalu G, Pawson T, Jan Y-N, Stainier DYR, Abdelilah-Seyfried S. 2001. Positional cloning of heart and soul reveals multiple roles for PKCλ in zebrafish organogenesis. Curr Biol 11: 14921502.
  • Jiang YJ, Brand M, Heisenberg CP, Beuchle D, Furutani-Seiki M, Kelsh RN, Warga RM, Granato M, Haffter P, Hammerschmidt M, Kane DA, Mullins MC, Odenthal J, van Eeden FJ, Nusslein-Volhard C. 1996. Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development 123: 205216.
  • Kalev-Zylinska ML, Horsfield JA, Flores MVC, Postlethwait JH, Vitas MR, Baas AM, Crosier PS, Crosier KE. 2002. runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis. Development 129: 20152030.
  • Karlen S, Rebagliati M. 2001. A morpholino phenocopy of the cyclops mutation. Genesis 30: 126128.
  • Karlstrom RO, Trowe T, Klostermann S, Baier H, Brand M, Crawford AD, Grunewald B, Haffter P, Hoffmann H, Meyer SU, Müller B, Richter S, van Eeden FJM, Nüsslein-Volhard C, Bonhoeffer F. 1996. Zebrafish mutations affecting retinotectal axon pathfinding. Development 123: 427438.
  • Keegan BR, Feldman JL, Lee DH, Koos DS, Ho RK, Stainier DYR, Yelon D. 2002. The enlongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo. Development 129: 16231632.
  • Kikuchi Y, Trinh LA, Reiter JF, Alexander J, Yelon D, Stainier DY. 2000. The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates the generation of endodermal precursors. Genes Dev 14: 12791289.
  • Kikuchi Y, Agathon A, Alexander J, Thisse C, Waldron S, Yelon D, Thisse B, Stainier DYR. 2001. casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafish. Genes Dev 15: 14931505.
  • Kishimoto Y, Lee K-H, Hammerschmidt M, Schulte-Merker S. 1997. The molecular nature of zebrafish swirl: Bmp2 function is essential during early dorsoventral patterning. Development 124: 44574466.
  • Knaut H, Werz C, Geisler R, Consortium TS, Nusslein-Volhard C. 2003. A zebrafish homolog of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature 421: 279282.
  • Kupperman E, An S, Osborn N, Waldron S, Stainier DYR. 2000. A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development. Nature 406: 192195.
  • Langenau DM, Traver D, Ferrando AA, Kutok JL, Aster JC, Kanki JP, Lin S, Prochownik E, Trede NS, Zon LI, Look AT. 2003. Myc-induced T cell leukemia in transgenic zebrafish. Science 299: 887890.
  • Langheinrich U, Hennen E, Scott G, Vacun G. 2002. Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling. Curr Biol 12: 20232028.
  • Lawson ND, Weinstein BM. 2002. In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev Biol 248: 307318.
  • Lawson ND, Sheer N, Pham VN, Kim CH, Chitnis AB, Campos-Ortega JA, Weinstein B. 2001. Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128: 36753683.
  • Lawson ND, Mugford JW, Diamond BA, Weinstein B. 2003. phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev 17: 13461351.
  • Lee RKK, Stainier DYR, Weinstein BM, Fishman MC. 1994. Cardiovascular development in the zebrafish. Development 120: 33613366.
  • Lee K-Y, Marden JJ, Thompson MS, MacLennan H, Kishimoto Y, Pratt SJ, Schulte-Merker S, Hammerschmidt M, Johnson SL, Postlethwaite JH. 1998. Cloning and genetic mapping of zebrafish BMP2. Dev Genet 23: 97103.
  • Lee K-Y, Huang H, Ju B, Yang H, Lin S. 2002. Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat Biotechnol 20: 795799.
  • Li QY, Newbury-Ecob RA, Terrett JA, Wilson DI, Curtis AR, Yi CH, Gebuhr T, Bullen PJ, Robson SC, Strachan T. 1997. Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nat Genet 15: 2129.
  • Liang D, Chan JR, Chin AJ, Smith A, Kelly C, Weinberg ES, Ge R. 2001. The role of vascular endothelial growth factor (VEGF) in vasculogenesis, angiogenesis, and hematopoiesis in zebrafish development. Mech Dev 108: 2943.
  • Liao EC, Paw BH, Oates AC, Pratt SJ, Postlethwait JH, Zon LI. 1998. SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes Dev 12: 621626.
  • Liao W, Ho C-Y, Yan YL, Postlethwait J, Stainier DYR. 2000a. Hhex and Scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. Development 127: 43034313.
  • Liao EC, Paw BH, Peters LL, Zapata A, Pratt SJ, Do CP, Lieschke G, Zon LI. 2000b. Hereditary spherocytosis in zebrafish riesling illustrates evolution of erythroid β-spectrin structure, and function in red cell morphogenesis and membrane stability. Development 127: 51235132.
  • Lieschke GJ, Oates AC, Crowhurst MO, Ward AC, Layton JE. 2001. Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish. Blood 98: 30873096.
  • Long Q, Meng A, Wang H, Jessen JR, Ferrell MJ, Lin S. 1997. GATA-1 expression pattern can be recapitulated in living transgenic zebrafish using GFP reporter gene. Development 124: 41054111.
  • Long S, Ahmad N, Rebagliati M. 2003. The zebrafish nodal-related gene southpaw is required for visceral and diencephalic left-right asymmetry. Development 130: 23032316.
  • Lux SE, Palek J. 1995. Disorders of the red cell membrane. In: Blood: principles and practice of hematology. Philadelphia: JB Lippincott Co. p 17011818.
  • Lyons SE, Lawson ND, Lei L, Bennett PE, Weinstein BM, Liu PP. 2002. A nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes. Proc Natl Acad Sci U S A 99: 54545459.
  • Ma C, Fan L, Ganassin R, Bols N, Collodi P. 2001. Production of zebrafish germ-line chimera from embryo cell cultures. Proc Natl Acad Sci U S A 98: 24612466.
  • Malicki J, Neuhauss SC, Schier AF, Solnica-Krezel L, Stemple DL, Stainier DY, Abdelilah S, Zwartkruis F, Rangini Z, Driever W. 1996a. Mutations affecting development of the zebrafish retina. Development 123: 263273.
  • Malicki J, Schier AF, Solnica-Krezel L, Stemple DL, Neuhauss SCF, Stainier DYR, Abdelilah S, Rangini Z, Zwartkruis F, Driever W. 1996b. Mutations affecting development of the zebrafish ear. Development 123: 275283.
  • Masai I, Heisenberg C-P, Barth KA, Macdonald R, Adamek S, Wilson SW. 1997. floating head and masterblind regulate neuronal patterning in the roof of the forebrain. Neuron 18: 4357.
  • Melby AE, Kimelman D, Kimmel CB. 1997. Spatial regulation of floating head expression in the developing notochord. Dev Dyn 209: 156165.
  • Milan DJ, Peterson TA, Ruskin JN, Peterson RT, MacRae CA. 2003. Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation 107: 13551358.
  • Montosi G, Donovan A, Totaro A, Garuti C, Pignatti E, Cassanelli S, Trenor CC, Gasparini P, Andrews NC, Poietrangelo A. 2001. Autosomal dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest 108: 619623.
  • Moolman JC, Corfield VA, Posen B, Ngumbela K, Seidman C, Brink PA, Watkins H. 1997. Sudden death due to troponin T mutations. J Am Coll Cardiol 29: 549555.
  • Muller F, Albert S, Blader P, Fischer N, Hallonet M, Strahle U. 2000. Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral midline of the CNS. Development 127: 33893897.
  • Nasevicius A, Ekker SC. 2000. Effective targeted gene 'knockdown' in zebrafish. Nat Genet 26: 216220.
  • Neuhauss SC, Sonica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Abdelilah S, Stainier DY, Driever W. 1996. Mutations affecting craniofacial development in zebrafish. Development 123: 357367.
  • Odenthal J, Haffter P, Vogelsang E, Brand M, van Eeden FJ, Furutani-Seiki M, Granato M, Hammerschmidt M, Heisenberg C-P, Jiang Y-J, Kane DA, Kelsh RN, Mullins MC, Warga RM, Allende M, Weinberg ES, Nusslein-Volhard C. 1996. Mutations affecting the formation of the notochord in the zebrafish, Danio rerio. Development 123: 103115.
  • Orkin SH, Zon LI. 1997. Genetics of erythropoiesis: induced mutations in mice and zebrafish. Annu Rev Genet 31: 3360.
  • Patton EE, Zon LI. 2001. The art and design of genetic screens: zebrafish. Nat Rev Genet 2: 956966.
  • Paw BH. 2001. Cloning of the zebrafish retsina blood mutation: a genetic model for dyserythropoiesis and erythroid cytokinesis. Blood Cells Mol Dis 27: 6264.
  • Paw BH, Davidson AJ, Zhou Y, Li R, Pratt SJ, Lee C, Trede NS, Brownlie A, Donovan A, Liao EC, Ziai JM, Drejer AH, Guo W, Kim CH, Gwynn B, Peters LL, Chernova MN, Alper SL, Zapata A, Wickramasinghe SN, Lee MJ, Lux SE, Fritz A, Postlethwait JH, Zon LI. 2003. Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nat Genet 34: 5964.
  • Pelster B, Burggren WW. 1996. Disruption of hemoglobin oxygen transport does not impact oxygen-dependent physiological processes in developing embryos of zebra fish (Danio rerio). Circ Res 79: 358362.
  • Person V, Kostin S, Suzuki K, Labeit S, Schaper K. 2000. Antisense oligonucleotide experiments elucidate the essential role of titin in sarcomere genesis in adult rat cardiomyocytes in long-term culture. J Cell Sci 113: 38513859.
  • Peterson RT, Mably JD, Chen J-N, Fishman MC. 2001. Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Curr Biol 11: 14811491.
  • Ransom DG, Haffter P, Odenthal J, Brownlie A, Vogelsang E, Kelsh RN, Brand M, van Eeden FJ, Furutani-Seiki M, Granato M, Hammerschmidt M, Heisenberg C-P, Jiang Y-J, Kane DA, Mullins MC, Nusslein-Volhard C. 1996. Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development 123: 311319.
  • Rawls JF, Frieda MR, McAdow AR, Gross JP, Clayton CM, Heyen CK, Johnson SL. 2003. Coupled mutagenesis screens and genetic mapping in zebrafish. Genetics 163: 9971009.
  • Rebagliati M, Toyama R, Haffter P, Dawid IB. 1998. cyclops encodes a nodal-related factor involved in midline signaling. Proc Natl Acad Sci U S A 95: 99329937.
  • Reifers F, Bohli H, Walsh EC, Crossley PH, Stainier DY. 1998. Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125: 23812395.
  • Reifers F, Walsh EC, Leger S, Stainier DYR, Brand M. 2000. Induction and differentiation of the zebrafish heart required fibroblast growth factor 8 (fgf8/acerebellar). Development 127: 225235.
  • Reiter JF, Alexander J, Rodaway A, Yelon D, Patient R, Holder N, Stainier DYR. 1999. Gata5 is required for the development of the heart and endoderm in zebrafish. Genes Dev 13: 29832995.
  • Reiter JF, Kikuchi Y, Stainier DYR. 2001a. Multiple roles for Gata5 in zebrafish endoderm formation. Development 128: 125135.
  • Reiter JF, Verkade H, Stainier DYR. 2001b. Bmp2b and Oep promote early myocardial differentiation through their regulation of gata5. Dev Biol 234: 330338.
  • Rodaway A, Takeda H, Koshida S, Broadbent J, Price B, Smith JC, Patient R, Holder N. 1999. Induction of the mesendoderm in the zebrafish germ ring by yolk cell-derived TGF-beta family signals and discrimination of mesoderm and endoderm by FGF. Development 126: 30673078.
  • Roman BL, Pham VN, Lawson ND, Kulik M, Childs S, Lekven AC, Garrity DM, Moon RT, Fishman M, Lechleider RJ, Weinstein B. 2002. Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development 129: 30093019.
  • Rottbauer W, Baker K, Wo ZG, Mohideen M-APK, Cantiello HF, Fishman MC. 2001. Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel α1 subunit. Dev Cell 1: 265275.
  • Rottbauer W, Saurin AJ, Lickert H, Shen X, Burns CG, Wo ZG, Kemler R, Kingston R, Wu C, Fishman M. 2002. Reptin and pontin antagonistically regulate heart growth in zebrafish embryos. Cell 111: 661672.
  • Sampath K, Rubinstein AL, Cheng AM, Liang JO, Fekany K, Sonica-Krezel L, Korzh V, Halpern ME, Wright CV. 1998. Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature 395: 185189.
  • Schier AF, Neuhauss SCF, Harvey M, Malicki J, Solnica-Krezel L, Stainier DYR, Zwartkruis F, Abdelilah S, Stemple DL, Rangini Z, Yang H, Driever W. 1996. Mutations affecting the development of the embryonic zebrafish brain. Development 123: 165178.
  • Schier AF, Neuhauss SC, Helde KA, Talbot WS, Driever W. 1997. The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail. Development 124: 327342.
  • Schulte-Merker S, van Eeden FJ, Halpern ME, Kimmel CB, Nusslein-Volhard C. 1994. no tail (ntl) is the zebrafish homolog of the mouse T (Brachyury) gene. Development 120: 10091015.
  • Sehnert AJ, Huq A, Weinstein BM, Walker C, Fishman M, Stainier DYR. 2002. Cardiac troponin T is essential in sarcomere assembly and cardiac contractility. Nat Genet 31: 106110.
  • Shafizadeh E, Paw BH, Foott H, Liao EC, Barut BA, Cope JJ, Zon LI, Lin S. 2002. Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models of severe congenital anemia due to protein 4.1 deficiency. Development 129: 43594370.
  • Solnica-Krezel L, Stemple DL, Mountcastle-Shah E, Rangini Z, Neuhauss SC, Malicki J, Schier AF, Stainier DY, Zwartkruis F, Abdelilah S, Driever W. 1996. Mutations affecting cell fates and cellular rearrangements during gastrulation. Development 123: 6780.
  • Stainier DYR, Lee RK, Fishman MC. 1993. Cardiovascular development in the zebrafish. Development 119: 3140.
  • Stainier DYR, Fouquet B, Chen J-N, Warren KS, Weinstein BM, Meiler SE, Mohideen M-APK, Neuhauss SCF, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Driever W, Fishman MC. 1996. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development 123: 285292.
  • Stemple DL, Solnica-Krezel L, Zwartkruis F, Neuhauss SC, Schier AF, Malicki J, Stainier DY, Abdelilah S, Rangini Z, Mountcastle-Shah E, Driever W. 1996. Mutations affecting development of the notochord in zebrafish. Development 123: 117128.
  • Stern H, Zon LI. 2003. Cancer genetics and drug discovery in the zebrafish. Nature Reviews Cancer 3: 533539.
  • Strahle U, Blader P, Henrique D, Ingham PW. 1993. Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in the cyclops mutant. Genes Dev 7: 14361446.
  • Stuart GW, McMurray JV, Westerfield M. 1988. Replication, integration, and stable germ-line transmission of foreign sequences injected into early zebrafish embryos. Development 103: 403412.
  • Summerton J, Weller D. 1997. Morpholino antisense oligomers: design, preparation, and properties. Antisense Nucleic Acid Drug Dev 7: 187195.
  • Sumoy L, Keasey JB, Dittman TD, Kimelman D. 1997. A role for notochord in axial vascular development revealed by analysis of phenotype and the expression of VEGR-2 in zebrafish flh and ntl embryos. Mech Dev 63: 1527.
  • Sun Z, Hopkins N. 2001. vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros and hindbrain. Genes Dev 15: 32173229.
  • Talbot WS, Trevarrow B, Halpern ME, Melby AE, Farr G, Postlethwait J, Jowett T, Kimmel CB, Kimelman D. 1995. A homeobox gene essential for zebrafish notochord development. Nature 378: 150157.
  • Thierfelder L, Watkins H, MacRae C, Lamas R, McKenna W, Vosberg HP, Seidman JG, Seidman CE. 1994. Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. Cell 77: 701712.
  • Thisse C, Zon LI. 2002. Organogenesis- heart and blood formation from the zebrafish point of view. Science 295: 457462.
  • Thisse B, Wright CV, Thisse C. 2000. Activin- and Nodal-related factors control anterio-posterior patterning of the zebrafish embryo. Nature 403: 425428.
  • Thomas JW, Touchman JW. 2002. Vertebrate genome sequencing: building a backbone for comparative genomics. Trends Genet 18: 104108.
  • Trede NS, Zon LI. 1998. Development of T-cells during fish embryogenesis. Dev Comp Immunol 22: 253263.
  • Trede NS, Zapata A, Zon LI. 2001. Fishing for lymphoid genes. Trends Immunol 22: 302307.
  • Udvadia AJ, Linney E. 2003. Windows into development: historic, current, and future perspective on transgenic zebrafish. Dev Biol 256: 117.
  • van der Ven PF, Bartsch JW, Gautel M, Jockusch H, Furst DO. 2000. A functional knock-out of titin results in defective myofibril assembly. J Cell Sci 113: 14051414.
  • van Eeden FJ, Granato M, Schach U, Brand M, Furutani-Seiki M, Haffter P, Hammerschmidt M, Heisenberg C-P, Jiang Y-J, Kane DA, Kelsh RN, Mullins MC, Odenthal J, Warga RM, Nusslein-Volhard C. 1996. Genetic analysis of fin formation in the zebrafish, Danio rerio. Development 123: 255262.
  • Varga ZM, Wegner J, Westerfield M. 1999. Anterior movement of ventral diencephalic precursors separates the primordial eye field in the neural plate and requires cyclops. Development 126: 55335546.
  • Walsh EC, Stainier DYR. 2001. UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish. Science 293: 16701673.
  • Wang H, Long Q, Marty SD, Sassa S, Lin S. 1998. A zebrafish model for hepatoerythropoietic porphyria. Nat Genet 20: 239243.
  • Warren KS, Baker K, Fishman MC. 2001. The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish. Am J Heart Circ Physiol 281: H1711H1719.
  • Weinstein BM, Stemple DL, Driever W, Fishman MC. 1995. gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat Med 1: 11431147.
  • Weinstein BM, Schier AF, Abdelilah S, Malicki J, Solnica-Krezel L, Stemple DL, Stainier DYR, Zwartkruis F, Driever W, Fishman MC. 1996. Hematopoietic mutations in the zebrafish. Development 123: 303309.
  • Whitfield TT, Granato M, van Eeden FJM, Schach U, Brand M, Furutani-Seiki M, Haffter P, Hammerschmidt M, Heisenberg C-P, Jiang Y-J, Kane DA, Kelsh RN, Mullins MC, Odenthal J, Nusslein-Volhard C. 1996. Mutations affecting development of the zebrafish inner ear and lateral line. Development 123: 241254.
  • Wienholds E, Schulte-Merker S, Walderich B, Plasterk RHA. 2002. Target-selected inactivation of the zebrafish rag1 gene. Science 297: 99101.
  • Willett CE, Cherry JJ, Steiner LA. 1997. Characterization and expression of the recombination activating genes (rag 1 and rag 2) of the zebrafish. Immunogenetics 45: 331341.
  • Willett CE, Cortes A, Zuasti A, Zapata AG. 1999. Early hematopoiesis and developing lymphoid organs in the zebrafish. Dev Dyn 214: 323336.
  • Wingert RA, Zon LI. 2003. Genetic dissection of hematopoiesis using the zebrafish. In: GodinI, CumanoA, editors. Hematopoietis Stem Cells. Georgetown, TX: Eurekah.
  • Xu X, Meiler SE, Zhong TP, Mohideen M, Crossley DA, Bruggren WW, Fishman MC. 2002. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nat Genet 30: 205209.
  • Yan YT, Gritsman K, Ding J, Burdine RD, Corrales JD, Price SM, Talbot WS, Schier AF, Shen MM. 1999. Conserved requirement for EGF-CFC gene in vertebrate left-right axis formation. Genes Dev 13: 25272537.
  • Yelon D, Horne SA, Stainier DY. 1999. Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish. Dev Biol 214: 11581161.
  • Yelon D, Ticho B, Halpern ME, Ruvinsky I, Ho RK, Silver LM, Stainier DYR. 2000. The bHLH transcription factor Hand2 plays parallel roles in zebrafish heart and pectoral fin development. Development 127: 25732582.
  • Zhang J, Talbot WS, Schier AF. 1998. Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell 92: 241251.
  • Zhong TP, Rosenberg M, Mohideen M-APK, Weinstein B, Fishman MC. 2000. gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science 287: 18201824.
  • Zhong TP, Childs S, Leu JP, Fishman M. 2001. Gridlock signalling pathway fashions the first embryonic artery. Nature 8: 216220.
  • Zon LI. 1995. Developmental biology of hematopoiesis. Blood 86: 28762891.