Reviews–A Peer Reviewed Forum
Start the clock! Circadian rhythms and development
Article first published online: 30 OCT 2006
Copyright © 2006 Wiley-Liss, Inc.
Volume 236, Issue 1, pages 142–155, January 2007
How to Cite
Vallone, D., Lahiri, K., Dickmeis, T. and Foulkes, N. S. (2007), Start the clock! Circadian rhythms and development. Dev. Dyn., 236: 142–155. doi: 10.1002/dvdy.20998
- Issue published online: 19 DEC 2006
- Article first published online: 30 OCT 2006
- Manuscript Accepted: 28 SEP 2006
- Centre National de la Recherche Scientifique
- Deutsche Forschungsgemeinschaft
- European Molecular Biology Organization
- cell cycle;
The contribution of timing cues from the environment to the coordination of early developmental processes is poorly understood. The day–night cycle represents one of the most important, regular environmental changes that animals are exposed to. A key adaptation that allows animals to anticipate daily environmental changes is the circadian clock. In this review, we aim to address when a light-regulated circadian clock first emerges during development and what its functions are at this early stage. In particular, do circadian clocks regulate early developmental processes? We will focus on results obtained with Drosophila and vertebrates, where both circadian clock and developmental control mechanisms have been intensively studied. Developmental Dynamics 236:142–155, 2007. © 2006 Wiley-Liss, Inc.