1097-0177/asset/DVDY_left.gif?v=1&s=b87335326ab8ecd1f573539da0b5fa6abef26532)
Research Article
You have full text access to this OnlineOpen article
Nuclear localization of the zebrafish tight junction protein nagie oko
Article first published online: 3 DEC 2007
DOI: 10.1002/dvdy.21389
Copyright © 2007 Wiley-Liss, Inc.
Additional Information
How to Cite
Bit-Avragim, N., Rohr, S., Rudolph, F., Van Der Ven, P., Fürst, D., Eichhorst, J., Wiesner, B. and Abdelilah-Seyfried, S. (2008), Nuclear localization of the zebrafish tight junction protein nagie oko. Dev. Dyn., 237: 83–90. doi: 10.1002/dvdy.21389
Publication History
- Issue published online: 19 DEC 2007
- Article first published online: 3 DEC 2007
- Manuscript Accepted: 22 OCT 2007
Funded by
- Helmholtz. Grant Number: VH-VI-152
REFERENCES
- , , , , , , . 2006. Elucidation of megalin/LRP2-dependent endocytic transport processes in the larval zebrafish pronephros. J Cell Sci 119: 2127–2137.
- , , , , . 2001. Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity. Nature 414: 638–643.
- , , , , , . 2004. The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells. Exp Cell Res 292: 51–66.
- , , , , , . 2003. Affinity purification of antibodies using Ni2+-resins on which inclusion body-forming proteins are immobilized. Protein Exp Purif 32: 147–150.
- , . 2007. Characterization of mammalian Par6 as a dual location protein. Mol Cell Biol 27: 4431–4443.
- , , , , , , , , . 2007. Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair. Cell Res 17: 100–116.
- , , , . 2006. The tight junction protein ZO-2 has several functional nuclear export signals. Exp Cell Res 312: 3323–3335.
- , , , . 1996. The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts. Proc Natl Acad Sci USA 93: 10779–10784.
- , , , , , , . 2004. Solution structure of atypical protein kinase C PB1 domain and its mode of interaction with ZIP/p62 and MEK5. J Biol Chem 279: 31883–31890.
- , , , , . 2001. Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature 414: 634–638.
- , , , , , , , , . 2001. Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis. Curr Biol 11: 1492–1502.
- , , , . 2002. Nuclear localization of the tight junction protein ZO-2 in epithelial cells. Exp Cell Res 274: 138–148.
- , , , , , , . 2004. Characterization of the tight junction protein ZO-2 localized at the nucleus of epithelial cells. Exp Cell Res 297: 247–258.
- , , , , , , . 2000. Molecular cloning and characterization of Pals, proteins associated with mLin-7. J Biol Chem 275: 11425–11431.
- , , , , . 1995. Stages of embryonic development of the zebrafish. Dev Dyn 203: 253–310.
- . 2004. Parsing the polarity code. Nat Rev Mol Cell Biol 5: 220–231.
- , , , , , . 2005. PATJ connects and stabilizes apical and lateral components of tight junctions in human intestinal cells. J Cell Sci 118: 4049–4057.
- , , , , . 1995. Identification of heterogeneous ribonucleoprotein A1 as a novel substrate for protein kinase C zeta. J Biol Chem 270: 15884–15891.
- , , , , . 1998. Mapping of a myosin-binding domain and a regulatory phosphorylation site in M-protein, a structural protein of the sarcomeric M band. Mol Biol Cell 9: 829–840.
- . 2001. Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity. Curr Opin Cell Biol 13: 641–648.
- , . 2006. oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo. Curr Biol 16: 945–957.
- , , , . 2001. Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Curr Biol 11: 1481–1491.
- , , . 2002. A ZO1-GFP fusion protein to study the dynamics of tight junctions in living cells. Histochem Cell Biol 117: 307–315.
- , , , , , , , , . 2002. The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost. J Cell Biol 157: 161–172.
- , , . 2006. Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis. Development 133: 107–115.
- , , . 2005. PATJ regulates tight junction formation and polarity in mammalian epithelial cells. J Cell Biol 168: 705–711.
- , , . 2006. Tight junctions and cell polarity. Annu Rev Cell Dev Biol 22: 207–235.
- , . 2003. Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development. Mech Dev 120: 1351–1383.
- , . 2006. The PAR-aPKC system: lessons in polarity. J Cell Sci 119: 979–987.
- , , , , , . 2002. aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization. J Cell Sci 115: 3565–3573.
- , . 1993. Crumbs and stardust act in a genetic pathway that controls the organization of epithelia in Drosophila melanogaster. Dev Biol 159: 311–326.
- , , . 1990. crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia. Cell 61: 787–799.
- . 2003. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 15: 740–746.
- , , , , , . 2003. The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B. J Biol Chem. 278: 2692–2700.
- , , . 2004. Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/stardust. J Biol Chem 279: 30715–30721.
- , . 2002. nagie oko, encoding a MAGUK-family protein, is essential for cellular patterning of the retina. Nat Genet 31: 150–-157.
- . 1994. The zebrafish book. Eugene: University of Oregon Press.
- , , . 2002. Phosphorylation of tyrosine 256 facilitates nuclear import of atypical protein kinase C. J Cell Biochem 85: 42–53.Direct Link:
- , , , . 1997. Transport of protein kinase C isoforms to the nucleus of PC12 cells by nerve growth factor: association of atypical zeta-PKC with the nuclear matrix. J Neurosci Res 49: 393–403.Direct Link:
- , , . 1997. Nucleolin is a protein kinase C-zeta substrate. Connection between cell surface signaling and nucleus in PC12 cells. J Biol Chem 272: 31130–31137.