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REFERENCES

  • Akhurst RJ, Lehnert SA, Faissner A, Duffie E. 1990. TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis. Development 108: 645656.
  • American Heart Association. 2003. Heart disease and stroke statistics - 2004. Update. Dallas, TX: American Heart Association.
  • Annes JP, Munger JS, Rifkin DB. 2003. Making sense of latent TGFbeta activation. J Cell Sci 116: 217224.
  • Bakin AV, Tomlinson AK, Bhowmick NA, Moses HL, Arteaga CL. 2000. Phosphatidylinositol 3-kinase function is required for transforming growth factor beta -mediated epithelial to mesenchymal transition and cell migration. J Biol Chem 275: 3680336810.
  • Bakin AV, Rinehart C, Tomlinson AK, Arteaga CL. 2002. p38 mitogen-activated protein kinase is required for TGFbeta-mediated fibroblastic transdifferentiation and cell migration. J Cell Sci 115: 31933206.
  • Bassing CH, Yingling JM, Howe DJ, Wang T, He WW, Gustafson ML, Shah P, Donahoe PK, Wang XF. 1994. A transforming growth factor beta type I receptor that signals to activate gene expression. Science 263: 8789.
  • Bhowmick NA, Ghiassi M, Bakin A, Aakre M, Lundquist CA, Engel ME, Arteaga CL, Moses HL. 2001a. Transforming growth factor-{beta}1 mediates epithelial to mesenchymal transdifferentiation through a Rhoa-dependent mechanism. Mol Biol Cell 12: 2736.
  • Bhowmick NA, Zent R, Ghiassi M, McDonnell M, Moses HL. 2001b. Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity. J Biol Chem 276: 4670746713.
  • Bhowmick NA, Ghiassi M, Aakre M, Brown K, Singh V, Moses HL. 2003. TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest. Proc Natl Acad Sci U S A 100: 1554815553.
  • Cheifetz S, Bellon T, Cales C, Vera S, Bernabeu C, Massague J, Letarte M. 1992. Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells. J Biol Chem 267: 1902719030.
  • Chen S, Lechleider RJ. 2004. Transforming growth factor-beta-induced differentiation of smooth muscle from a neural crest stem cell line. Circ Res 94: 11951202.
  • Compton LA, Potash DA, Mundell NA, Barnett JV. 2006. Transforming growth factor-beta induces loss of epithelial character and smooth muscle cell differentiation in epicardial cells. Dev Dyn 235: 8293.
  • Compton LA, Potash DA, Brown CB, Barnett JV. 2007. Coronary vessel development is dependent on the type III transforming growth factor beta receptor. Circ Res 101: 784791.
  • Darland DC, D'Amore PA. 2001. TGF beta is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells. Angiogenesis 4: 1120.
  • Deaton RA, Su C, Valencia TG, Grant SR. 2005. Transforming growth factor-beta 1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAP kinase. J Biol Chem 280: 3117231181.
  • Desgrosellier JS, Mundell NA, McDonnell MA, Moses HL, Barnett JV. 2005. Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation. Dev Biol 280: 201210.
  • Dettman RW, Denetclaw W Jr, Ordahl CP, Bristow J. 1998. Common epicardial origin of coronary vascular smooth muscle, perivascular fibroblasts, and intermyocardial fibroblasts in the avian heart. Dev Biol 193: 169181.
  • Dickson MC, Slager HG, Duffie E, Mummery CL, Akhurst RJ. 1993. RNA and protein localisations of TGF beta 2 in the early mouse embryo suggest an involvement in cardiac development. Development 117: 625639.
  • Ebner R, Chen RH, Shum L, Lawler S, Zioncheck TF, Lee A, Lopez AR, Derynck R. 1993. Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor. Science 260: 13441348.
  • Edlund S, Landstrom M, Heldin CH, Aspenstrom P. 2002. Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA. Mol Biol Cell 13: 902914.
  • Ghosh S, Brauer PR. 1996. Latent transforming growth factor-beta is present in the extracellular matrix of embryonic hearts in situ. Dev Dyn 205: 126134.
  • Grainger DJ, Metcalfe JC, Grace AA, Mosedale DE. 1998. Transforming growth factor-beta dynamically regulates vascular smooth muscle differentiation in vivo. J Cell Sci 111(Pt 19): 29772988.
  • Hirschi KK, Rohovsky SA, D'Amore PA. 1998. PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. J Cell Biol 141: 805814.
  • Hirschi KK, Lai L, Belaguli NS, Dean DA, Schwartz RJ, Zimmer WE. 2002. Transforming growth factor-beta induction of smooth muscle cell phenotype requires transcriptional and post-transcriptional control of serum response factor. J Biol Chem 277: 62876295.
  • Ho E, Shimada Y. 1978. Formation of the epicardium studied with the scanning electron microscope. Dev Biol 66: 579585.
  • Holifield JS, Arlen AM, Runyan RB, Tomanek RJ. 2004. TGF-beta1, -beta2 and -beta3 cooperate to facilitate tubulogenesis in the explanted quail heart. J Vasc Res 41: 491498.
  • Hu PP, Datto MB, Wang XF. 1998. Molecular mechanisms of transforming growth factor-beta signaling. Endocr Rev 19: 349363.
  • Jakowlew SB, Ciment G, Tuan RS, Sporn MB, Roberts AB. 1994. Expression of transforming growth factor-beta 2 and beta 3 mRNAs and proteins in the developing chicken embryo. Differentiation 55: 105118.
  • Jat PS, Noble MD, Ataliotis P, Tanaka Y, Yannoutsos N, Larsen L, Kioussis D. 1991. Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc Natl Acad Sci U S A 88: 50965100.
  • Kalluri R, Neilson EG. 2003. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 17761784.
  • Komiyama M, Ito K, Shimada Y. 1987. Origin and development of the epicardium in the mouse embryo. Anat Embryol (Berl) 176: 183189.
  • Kretzschmar M, Massague J. 1998. SMADs: mediators and regulators of TGF-beta signaling. Curr Opin Genet Dev 8: 103111.
  • Kuhn HJ, Liebherr G. 1988. The early development of the epicardium in Tupaia belangeri. Anat Embryol (Berl) 177: 225234.
  • Lepilina A, Coon AN, Kikuchi K, Holdway JE, Roberts RW, Burns CG, Poss KD. 2006. A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. Cell 127: 607619.
  • Lin HY, Moustakas A. 1994. TGF-beta receptors: structure and function. Cell Mol Biol 40: 337349.
  • Lin HY, Wang XF, Ng-Eaton E, Weinberg RA, Lodish HF. 1992. Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase. Cell 68: 775785.
  • Lopez-Casillas F, Cheifetz S, Doody J, Andres JL, Lane WS, Massague J. 1991. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system. Cell 67: 785795.
  • Lu J, Landerholm TE, Wei JS, Dong XR, Wu SP, Liu X, Nagata K, Inagaki M, Majesky MW. 2001. Coronary smooth muscle differentiation from proepicardial cells requires rhoA-mediated actin reorganization and p160 rho-kinase activity. Dev Biol 240: 404418.
  • Mack CP, Somlyo AV, Hautmann M, Somlyo AP, Owens GK. 2001. Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization. J Biol Chem 276: 341347.
  • Masszi A, Di Ciano C, Sirokmany G, Arthur WT, Rotstein OD, Wang J, McCulloch CA, Rosivall L, Mucsi I, Kapus A. 2003. Central role for Rho in TGF-beta1-induced alpha-smooth muscle actin expression during epithelial-mesenchymal transition. Am J Physiol Renal Physiol 284: F911F924.
  • McAllister KA, Grogg KM, Johnson DW, Gallione CJ, Baldwin MA, Jackson CE, Helmbold EA, Markel DS, McKinnon WC, Murrell J, et al. 1994. Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. Nat Genet 8: 345351.
  • Mikawa T, Fischman DA. 1992. Retroviral analysis of cardiac morphogenesis: discontinuous formation of coronary vessels. Proc Natl Acad Sci U S A 89: 95049508.
  • Mikawa T, Gourdie RG. 1996. Pericardial mesoderm generates a population of coronary smooth muscle cells migrating into the heart along with ingrowth of the epicardial organ. Dev Biol 174: 221232.
  • Molin DG, Bartram U, Van der Heiden K, Van Iperen L, Speer CP, Hierck BP, Poelmann RE, Gittenberger-de-Groot AC. 2003. Expression patterns of Tgfbeta1–3 associate with myocardialisation of the outflow tract and the development of the epicardium and the fibrous heart skeleton. Dev Dyn 227: 431444.
  • Morabito CJ, Dettman RW, Kattan J, Collier JM, Bristow J. 2001. Positive and negative regulation of epicardial-mesenchymal transformation during avian heart development. Dev Biol 234: 204215.
  • Munoz-Chapuli R, Gonzalez-Iriarte M, Carmona R, Atencia G, Macias D, Perez-Pomares JM. 2002. Cellular precursors of the coronary arteries. Tex Heart Inst J 29: 243249.
  • Nahirney PC, Mikawa T, Fischman DA. 2003. Evidence for an extracellular matrix bridge guiding proepicardial cell migration to the myocardium of chick embryos. Dev Dyn 227: 511523.
  • Olivey HE, Compton LA, Barnett JV. 2004. Coronary vessel development: the epicardium delivers. Trends Cardiovasc Med 14: 247251.
  • Olivey HE, Mundell NA, Austin AF, Barnett JV. 2006. Transforming growth factor-beta stimulates epithelial-mesenchymal transformation in the proepicardium. Dev Dyn 235: 5059.
  • Owens GK, Kumar MS, Wamhoff BR. 2004. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84: 767801.
  • Pelton RW, Johnson MD, Perkett EA, Gold LI, Moses HL. 1991. Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 mRNA and protein in the murine lung. Am J Respir Cell Mol Biol 5: 522530.
  • Poelmann RE, Gittenberger-de Groot AC, Mentink MM, Bokenkamp R, Hogers B. 1993. Development of the cardiac coronary vascular endothelium, studied with antiendothelial antibodies, in chicken-quail chimeras. Circ Res 73: 559568.
  • Poss KD. 2007. Getting to the heart of regeneration in zebrafish. Semin Cell Dev Biol 18: 3645.
  • Roberts AB, Sporn MB. 1990. The transforming growth factor-betas. In: SpornMB, RobertsAB, editors. Peptide growth factors and their receptors. New York: Springer-Verlag. p 419472.
  • Sanford LP, Ormsby I, Gittenberger-de Groot AC, Sariola H, Friedman R, Boivin GP, Cardell EL, Doetschman T. 1997. TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes. Development 124: 26592670.
  • Shi Y, Massague J. 2003. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685700.
  • Sinha S, Hoofnagle MH, Kingston PA, McCanna ME, Owens GK. 2004. Transforming growth factor-beta1 signaling contributes to development of smooth muscle cells from embryonic stem cells. Am J Physiol Cell Physiol 287: C1560C1568.
  • Tomanek RJ. 2005. Formation of the coronary vasculature during development. Angiogenesis 8: 273284.
  • Wang XF, Lin HY, Ng-Eaton E, Downward J, Lodish HF, Weinberg RA. 1991. Expression cloning and characterization of the TGF-beta type III receptor. Cell 67: 797805.
  • Ward SM, Gadbut AP, Tang D, Papageorge AG, Wu L, Li G, Barnett JV, Galper JB. 2002. TGFbeta regulates the expression of G alpha(i2) via an effect on the localization of ras. J Mol Cell Cardiol 34: 12171226.
  • Xie L, Law BK, Chytil AM, Brown KA, Aarke ME, Moses HL. 2004. Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia 6: 603610.