Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development
Article first published online: 21 JAN 2008
Copyright © 2008 Wiley-Liss, Inc.
Volume 237, Issue 2, pages 339–353, February 2008
How to Cite
Ratzka, A., Kalus, I., Moser, M., Dierks, T., Mundlos, S. and Vortkamp, A. (2008), Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development. Dev. Dyn., 237: 339–353. doi: 10.1002/dvdy.21423
- Issue published online: 21 JAN 2008
- Article first published online: 21 JAN 2008
- Manuscript Accepted: 20 NOV 2007
- Deutsche Forschungsgemeinschaft. Grant Number: DFG-Vo620/6-1
The Supplementary Material referred to in this article can be viewed at www.interscience.wiley.com/jpages/1058-8388/suppmat
|dvdy21423-DVDY21422FigureS1.tif||1785K||Fig.S1:Quantitative RT-PCR analysis ofSulf1andSulf2expression levels normalized toGapdh(A) Sulf1 is reduced to 3% in homozygous Sulf1 gt-mutants compared to wild-type controls. (B) Sulf2 is reduced to 0.4% in homozygous Sulf2 gt-mutants compared to wild-type controls. (C,D) No compensatory change in expression level of Sulf1 (C) or Sulf2 (D) were observed in Sulf1;Sulf2 compound mutants, compared to double heterozygous controls. Each bar represents an E14.5 limb cDNA sample from individual animals.|
|dvdy21423-DVDY21422FigureS2.tif||2396K||Supporting Information file dvdy21423-DVDY21422FigureS2.tif|
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