Patterns & Phenotypes
Vestigial expression in the Drosophila embryonic central nervous system
Article first published online: 12 AUG 2008
Copyright © 2008 Wiley-Liss, Inc.
Volume 237, Issue 9, pages 2483–2489, September 2008
How to Cite
Guss, K. A., Mistry, H. and Skeath, J. B. (2008), Vestigial expression in the Drosophila embryonic central nervous system. Dev. Dyn., 237: 2483–2489. doi: 10.1002/dvdy.21664
- Issue published online: 26 AUG 2008
- Article first published online: 12 AUG 2008
- Manuscript Accepted: 11 MAR 2008
- Research & Development Committee, Dickinson College
- NSF MRI/RUI. Grant Number: 0320606
- NINDS. Grant Number: RO1-NS-036570
- central nervous system;
- ventral nerve cord;
The Drosophila central nervous system is an excellent model system in which to resolve the genetic and molecular control of neuronal differentiation. Here we show that the wing selector vestigial is expressed in discrete sets of neurons. We track the axonal trajectories of VESTIGIAL-expressing cells in the ventral nerve cord and show that these cells descend from neuroblasts 1-2, 5-1, and 5-6. In addition, along the midline, VESTIGIAL is expressed in ventral unpaired median motorneurons and cells that may descend from the median neuroblast. These studies form the requisite descriptive foundation for functional studies addressing the role of vestigial during interneuron differentiation. Developmental Dynamics 237:2483–2489, 2008. © 2008 Wiley-Liss, Inc.