Patterns & Phenotypes
Properties of branchiomeric and somite-derived muscle development in Tbx1 mutant embryos
Article first published online: 24 SEP 2008
Copyright © 2008 Wiley-Liss, Inc.
Special Issue: Special Focus on the Extracellular Matrix, in Memory of Dr. Elizabeth D. Hay
Volume 237, Issue 10, pages 3071–3078, October 2008
How to Cite
Grifone, R., Jarry, T., Dandonneau, M., Grenier, J., Duprez, D. and Kelly, R. G. (2008), Properties of branchiomeric and somite-derived muscle development in Tbx1 mutant embryos. Dev. Dyn., 237: 3071–3078. doi: 10.1002/dvdy.21718
- Issue published online: 24 SEP 2008
- Article first published online: 24 SEP 2008
- Manuscript Accepted: 27 JUL 2008
- Association Française contre les Myopathies
- Inserm Avenir program
- Fondation pour la Recherche Médicale
Additional Supporting Information may be found in the online version of this article.
|DVDY21718SuppFigS1.tif||12762K||Supp. Fig. S1. Fiber type analysis in <I>Tbx1</I> mutant embryos. <B>A:</B> Myosin heavy chain type IIA and type I distribution after immunohistochemistry on sagittal cryosections through the pharyngeal region of 4-month-old control and <I>Tbx1</I><SUP>+/−</SUP> mice including 5× magnification of the boxed regions. No myosin heavy chain (MHC) type I or type IIA fibers are detected in the pharyngeal constrictor (pc) muscles of control or <I>Tbx1</I><SUP>+/−</SUP> embryos. <B>B:</B> MHC I distribution in transverse cryosections through hindlimbs of E17.5 <I>Tbx1</I><SUP>+/+</SUP>, <I>Tbx1</I><SUP>+/−</SUP> and <I>Tbx1</I><SUP>−/−</SUP> embryos. t, tibia; f, fibula. Scale bars = 200 μm.|
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