Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern
Version of Record online: 19 MAR 2009
Copyright © 2009 Wiley-Liss, Inc.
Volume 238, Issue 4, pages 812–825, April 2009
How to Cite
Lee, H. J., Pazin, D. E., Kahlon, R. S., Correa, S. M. and Albrecht, K. H. (2009), Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern. Dev. Dyn., 238: 812–825. doi: 10.1002/dvdy.21902
- Issue online: 19 MAR 2009
- Version of Record online: 19 MAR 2009
- Manuscript Accepted: 5 JAN 2009
- Department of Medicine, BUSM (Pilot Project)
- National Institute of Child Health and Human Development. Grant Number: HD042779
- American Cancer Society Research Scholar Grant. Grant Number: 06-033-01-DDC
Additional Supporting information may be found in the online version of this article.
|DVDY_21902_sm_SupplFigS1.tif||34173K||Supp. Fig. S1. Analysis of Sprr2d and 1700106J16Rik expression in sex reversed XYPOS gonads. Sprr2d and 1700106J16Rik expression in embryonic days (E) 13.25–13.5 gonad/mesonephros complexes was analyzed by whole-mount in situ hybridization (WISH). Sprr2d (left panels) was not detected in any gonads at this stage, which is similar to wild-type. 1700106J16Rik expression (right panels) was detected throughout XYPOS ovaries and was essentially indistinguishable from wild-type XX ovaries. In XYPOS ovotestes, 1700106J16Rik was expressed similar to wild-type XX ovaries in the ovarian regions lacking testis cords, but was greatly reduced in testicular regions with cords (within the black dotted circle). 1700106J16Rik was not detected in XYPOS Tg4 ǒrescuedö testes. In each panel, the gonad is located above, and the mesonephros below, the white dotted line. A, anterior; P, posterior. For XYPOS ovotestes analyzed for Sprr2d expression n = 3, for all others n ≤4.|
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