C. Davey and A. Tallafuss contributed equally to this study.
Patterns & Phenotypes
You have full text access to this OnlineOpen article
Differential expression of neuroligin genes in the nervous system of zebrafish
Article first published online: 8 JAN 2010
DOI: 10.1002/dvdy.22195
Copyright © 2010 Wiley-Liss, Inc.
Additional Information
How to Cite
Davey, C., Tallafuss, A. and Washbourne, P. (2010), Differential expression of neuroligin genes in the nervous system of zebrafish. Dev. Dyn., 239: 703–714. doi: 10.1002/dvdy.22195
- †
C. Davey and A. Tallafuss contributed equally to this study.
Publication History
- Issue published online: 22 JAN 2010
- Article first published online: 8 JAN 2010
- Manuscript Accepted: 20 NOV 2009
Funded by
- National Institute of Neurological Disorders. Grant Number: R01NS065795
- NIH
REFERENCES
- , . 2006. Telomeres, chromosome instability and cancer. Nucleic Acids Res 34: 2408–2417.
- , , , , , . 2009. Neuroligin1: a cell adhesion molecule that recruits PSD-95 and NMDA receptors by distinct mechanisms during synaptogenesis. Neural Dev 4: 17.
- , , , , , , . 2002. SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science 297: 1525–1531.
- , , , , , , . 2008. Bridging the synaptic gap: neuroligins and neurexin I in Apis mellifera. PLoS One 3: e3542.
- , , , . 2001. Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression. Biochem J 356: 581–588.
- , , , , , . 2008. Unusually rapid evolution of Neuroligin-4 in mice. Proc Natl Acad Sci USA 105: 6421–6426.
- , . 1995. The first retinal axons and their microenvironment in zebrafish: cryptic pioneers and the pretract. J Neurosci 15: 2935–2947.
- , , . 2009. Automated identification of conserved synteny after whole-genome duplication. Genome Res 19: 1497–1505.
- , , , . 2004. Disorder-associated mutations lead to functional inactivation of neuroligins. Hum Mol Genet 13: 1471–1477.
- , , . 2005. Control of excitatory and inhibitory synapse formation by neuroligins. Science 307: 1324–1328.
- , , , , , , . 2003. Genome duplication, subfunction partitioning, and lineage divergence: Sox9 in stickleback and zebrafish. Dev Dyn 228: 480–489.
- , , , , , , . 2003. Neurexin mediates the assembly of presynaptic terminals. Nat Neurosci 6: 708–716.
- , , , , , . 2002. Development of the locomotor network in zebrafish. Prog Neurobiol 68: 85–111.
- , , , . 2002. Evidence for a widespread brain stem escape network in larval zebrafish. J Neurophysiol 87: 608–614.
- . 1995. The origin and function of the mammalian Y chromosome and Y-borne genes: an evolving understanding. Bioessays 17: 311–320.
- , . 1999. Retinal neurogenesis: the formation of the initial central patch of postmitotic cells. Dev Biol 207: 309–321.
- , , , , , , . 1995. Neuroligin 1: a splice site-specific ligand for beta-neurexins. Cell 81: 435–443.
- , , . 1996. Structures, alternative splicing, and neurexin binding of multiple neuroligins. J Biol Chem 271: 2676–2682.
- , , , . 2004. Synaptic scaffolding molecule is involved in the synaptic clustering of neuroligin. Mol Cell Neurosci 27: 497–508.
- , , , , , , , , . 1997. Binding of neuroligins to PSD-95. Science 277: 1511–1515.
- , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . 2004. Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype. Nature 431: 946–957.
- , , , , , , , , , , . 2003. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat Genet 34: 27–29.
- , , . 2001. mosaic eyes: a zebrafish gene required in pigmented epithelium for apical localization of retinal cell division and lamination. Development 128: 95–105.
- , , , , , , , , , , , . 2008. Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals. Proc Natl Acad Sci USA 105: 9087–9092.
- , , , , , , , , , . 2006. NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Nat Neurosci 9: 1294–1301.
- , , , , . 1995. Stages of embryonic development of the zebrafish. Dev Dyn 203: 253–310.
- , , , , , , , , , , , , , , , , , , . 2004. X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family. Am J Hum Genet 74: 552–557.
- , , , , , , , , . 2005. Neuroligins mediate excitatory and inhibitory synapse formation: involvement of PSD-95 and neurexin-1beta in neuroligin-induced synaptic specificity. J Biol Chem 280: 17312–17319.
- , , , , . 2004. The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin. Neuropharmacology 47: 724–733.
- , . 2005. Postsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter. Proc Natl Acad Sci USA 102: 6137–6142.
- , , , , , , , , , , . 2008. Synapse formation and clustering of neuroligin-2 in the absence of GABAA receptors. Proc Natl Acad Sci USA 105: 13151–13156.
- , , , , . 2000. The structure and expression of the human neuroligin-3 gene. Gene 246: 303–310.
- , , , , . 2009. Glutamate drives the touch response through a rostral loop in the spinal cord of zebrafish embryos. Dev Neurobiol 69: 780–795.
- . 2007. The zebrafish genome in context: ohnologs gone missing. J Exp Zool B Mol Dev Evol 308: 563–577.
- , , , , , , , , . 2000. Zebrafish comparative genomics and the origins of vertebrate chromosomes. Genome Res 10: 1890–1902.
- , , , , . 2005. A cytoplasmic motif targets neuroligin-1 exclusively to dendrites of cultured hippocampal neurons. Eur J Neurosci 22: 2381–2386.
- , , , , . 2000. Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. Cell 101: 657–669.
- , , , . 1999. Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proc Natl Acad Sci USA 96: 1100–1105.
- . 2008. Neuroligins and neurexins link synaptic function to cognitive disease. Nature 455: 903–911.
- , . 2008. High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc 3: 59–69.
- , , . 2004. Neuroligin 2 is exclusively localized to inhibitory synapses. Eur J Cell Biol 83: 449–456.
- , , , , , , , , . 2006. Neuroligins determine synapse maturation and function. Neuron 51: 741–754.
- . 2000. The zebrafish book. Eugene OR: Institute for Neuroscience, University of Oregon.
- , , , , , , , , , , , , . 2005. Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients. Mol Psychiatry 10: 329–332.

1097-0177/asset/DVDY_left.gif?v=1&s=b87335326ab8ecd1f573539da0b5fa6abef26532)
1097-0177/asset/cover.gif?v=1&s=a30853283ce4b85446696e388141e1b70e2222b2)