Churchill and Sip1a repress fibroblast growth factor signaling during zebrafish somitogenesis
Version of Record online: 23 DEC 2009
Copyright © 2009 Wiley-Liss, Inc.
Volume 239, Issue 2, pages 548–558, February 2010
How to Cite
Kok, F. O., Shepherd, I. T. and Sirotkin, H. I. (2010), Churchill and Sip1a repress fibroblast growth factor signaling during zebrafish somitogenesis. Dev. Dyn., 239: 548–558. doi: 10.1002/dvdy.22201
- Issue online: 22 JAN 2010
- Version of Record online: 23 DEC 2009
- Manuscript Accepted: 20 NOV 2009
- NIH. Grant Number: RO1HD043998
- 1991. Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66: 257–270. , , .
- 2003. Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Dev Cell 4: 395–406. , , , , , , .
- 2001. Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev 15: 2642–2647. , , , , , .
- 2001. Fibroblast growth factor signaling in Caenorhabditis elegans. Bioessays 23: 1120–1130. , , .
- 2005. Fibroblast growth factor signaling during early vertebrate development. Endocr Rev 26: 63–77. , .
- 2007. Understanding the somitogenesis clock: what's missing? Mech Dev 124: 501–517. .
- 2001. FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev Cell 1: 37–49. , .
- 2001. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell 7: 1267–1278. , , , , , , , , .
- 1978. Somite abnormalities caused by short heat shocks to pre-neurula stages of Xenopus laevis. J Embryol Exp Morphol 45: 283–294. .
- 1976. A clock and wavefront model for control of the number of repeated structures during animal morphogenesis. J Theor Biol 58: 455–476. , .
- 2003. Roles of FGF receptors in mammalian development and congenital diseases. Birth Defects Res C Embryo Today 69: 286–304. , .
- 2000. A clock-work somite. Bioessays 22: 72–83. , .
- 2003. Periodic notch inhibition by lunatic fringe underlies the chick segmentation clock. Nature 421: 275–278. , , , , , .
- 2008. Zebrafish sip1a and sip1b are essential for normal axial and neural patterning. Dev Dyn 237: 1060–1069. , , , .
- 2005. Control of the segmentation process by graded MAPK/ERK activation in the chick embryo. Proc Natl Acad Sci U S A 102: 11343–11348. , , , , .
- 2001. Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis 30: 154–156. , , .
- 2001. FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Cell 106: 219–232. , , .
- 1998. Eph signaling is required for segmentation and differentiation of the somites. Genes Dev 12: 3096–3109. , , , , , , , , .
- 1998. Waves of mouse Lunatic fringe expression, in four-hour cycles at two-hour intervals, precede somite boundary formation. Curr Biol 8: 1027–1030. , , .
- 1997. A role for FGF-8 in the dorsoventral patterning of the zebrafish gastrula. Development 124: 4253–4264. , , .
- 2001. sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish. Development 128: 2175–2186. , , , , .
- 2004. Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. Development 131: 2853–2864. , , , .
- 2004. The vertebrate segmentation clock. Curr Opin Genet Dev 14: 407–414. , .
- 2005. Fgf8 drives myogenic progression of a novel lateral fast muscle fibre population in zebrafish. Development 132: 4211–4222. , , .
- 2000. Control of her1 expression during zebrafish somitogenesis by a delta-dependent oscillator and an independent wave-front activity. Genes Dev 14: 1678–1690. , , .
- 2002. her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis. Development 129: 1175–1183. , , , , .
- 2007. Amotl2 is essential for cell movements in zebrafish embryo and regulates c-Src translocation. Development 134: 979–988. , , , , , , , , , , , , .
- 2000. Notch signalling and the synchronization of the somite segmentation clock. Nature 408: 475–479. , , , , , .
- 1992. Induction of dorsal and ventral mesoderm by ectopically expressed Xenopus basic fibroblast growth factor. Development 114: 261–269. , .
- 1995. Stages of embryonic development of the zebrafish. Dev Dyn 203: 253–310. , , , , .
- 2008. Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation. Dev Biol 319: 370–383. , , , , , , , .
- 1994. Mesoderm induction by activin requires FGF-mediated intracellular signals. Development 120: 463–472. , .
- 2007. Embryonic neural inducing factor churchill is not a DNA-binding zinc finger protein: solution structure reveals a solvent-exposed beta-sheet and zinc binuclear cluster. J Mol Biol 371: 1274–1289. , , , , .
- 2007a. Expression and regulation of the zinc finger transcription factor Churchill during zebrafish development. Gene Expr Patterns 7: 645–650. , , , .
- 2007b. Churchill regulates cell movement and mesoderm specification by repressing Nodal signaling. BMC Dev Biol 7: 120. , , .
- 2005. Involvement of SIP1 in positioning of somite boundaries in the mouse embryo. Dev Dyn 234: 332–338. , , , , .
- 1998. The lunatic fringe gene is a target of the molecular clock linked to somite segmentation in avian embryos. Curr Biol 8: 979–982. , , , .
- 2004. XSIP1 is essential for early neural gene expression and neural differentiation by suppression of BMP signaling. Dev Biol 275: 258–267. , , , .
- 2002. Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish. Development 129: 2929–2946. , .
- 1997. Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis. Cell 91: 639–648. , , , .
- 2003. Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway. EMBO J 22: 2443–2452. .
- 2003. Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J 22: 2453–2462. , , , .
- 2001. Vertebrate somitogenesis. Annu Rev Cell Dev Biol 17: 311–350. .
- 2003. The segmentation clock: converting embryonic time into spatial pattern. Science 301: 328–330. .
- 2001. Zebrafish lunatic fringe demarcates segmental boundaries. Mech Dev 105: 175–180. , , , , , , .
- 2004. Sequence and embryonic expression of three zebrafish fringe genes: lunatic fringe, radical fringe, and manic fringe. Dev Dyn 231: 621–630. , , , , .
- 1998. Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125: 2381–2395. , , , , , .
- 1999. New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites. EMBO J 18: 5073–5084. , , , , , , , .
- 2001. The making of the somite: molecular events in vertebrate segmentation. Nat Rev Genet 2: 835–845. , .
- 2002. Morphological boundary forms by a novel inductive event mediated by Lunatic fringe and Notch during somitic segmentation. Development 129: 3633–3644. , , .
- 2001. Fgf/MAPK signalling is a crucial positional cue in somite boundary formation. Development 128: 4873–4880. , , , , , .
- 2003. Transcriptional oscillation of lunatic fringe is essential for somitogenesis. Genes Dev 17: 912–925. , , , .
- 2003. Churchill, a zinc finger transcriptional activator, regulates the transition between gastrulation and neurulation. Cell 115: 603–613. , , .
- 2006. Xenopus laevis POU91 protein, an Oct3/4 homologue, regulates competence transitions from mesoderm to neural cell fates. EMBO J 25: 3664–3674. , , , .
- 1999. Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev 13: 1834–1846. , , , .
- 1996. branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching. Cell 87: 1091–1101. , , .
- 1994. Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev 8: 174–189. , , , , , .
- 2005. Functions and regulations of fibroblast growth factor signaling during embryonic development. Dev Biol 287: 390–402. , .
- 1993. Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos. Development 119: 1203–1215. , , , .
- 2007. XSip1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms. Dev Biol 306: 34–49. , , , , , , , , , , , .
- 1999. SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5′-CACCT sequences in candidate target genes. J Biol Chem 274: 20489–20498. , , , , , , , , , , , .
- 2007. FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development 134: 4033–4041. , , , .
- 1996. Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos. Development 122: 271–280. , , , , , , , , .
- 1998. Zebrafish paraxial protocadherin is a downstream target of spadetail involved in morphogenesis of gastrula mesoderm. Development 125: 3389–3397. , , , , , .
- 2002. Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8. Dev Cell 3: 425–437. , , , .