Patterns & Phenotypes
Phylogeny of the teashirt-related zinc finger (tshz) gene family and analysis of the developmental expression of tshz2 and tshz3b in the zebrafish
Article first published online: 27 JAN 2010
Copyright © 2010 Wiley-Liss, Inc.
Volume 239, Issue 3, pages 1010–1018, March 2010
How to Cite
Santos, J. S., Fonseca, N. A., Vieira, C. P., Vieira, J. and Casares, F. (2010), Phylogeny of the teashirt-related zinc finger (tshz) gene family and analysis of the developmental expression of tshz2 and tshz3b in the zebrafish. Dev. Dyn., 239: 1010–1018. doi: 10.1002/dvdy.22228
- Issue published online: 11 FEB 2010
- Article first published online: 27 JAN 2010
- Manuscript Accepted: 14 DEC 2009
- Spanish Ministry of Science and Innovation. Grant Number: BFU2006-00349
- Consolider Grant ‘Genes to Shape’
- tshz gene family;
The tshz genes comprise a family of evolutionarily conserved transcription factors. However, despite the major role played by Drosophila tsh during the development of the fruit fly, the expression and function of other tshz genes have been analyzed in a very limited set of organisms and, therefore, our current knowledge of these genes is still fragmentary. In this study, we perform detailed phylogenetic analyses of the tshz genes, identify the members of this gene family in zebrafish and describe the developmental expressions of two of them, tshz2 and tshz3b, and compare them with meis1, meis2.1, meis2.2, pax6a, and pax6b expression patterns. The expression patterns of these genes define a complex set of coexpression domains in the developing zebrafish brain where their gene products have the potential to interact. Developmental Dynamics 239:1010–1018, 2010. © 2010 Wiley-Liss, Inc.